Sfoglia per Rivista SCIENCE TRANSLATIONAL MEDICINE
Adducin and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin. Part 2: Clinical Studies
2010-01-01 Lanzani, C; Citterio, L; Glorioso, N; Manunta, Paolo; Tripodi, G; Salvi, E; DELLI CARPINI, S; Ferrandi, M; Messaggio, E; Staessen, Ja; Cusi, D; Macciardi, F; Argiolas, G; Valentini, G; Ferrari, P; BIANCHI G., also on behalf of OASIS HT Investigators
Brain-released alarmins and stress response synergize in accelerating atherosclerosis progression after stroke
2018-01-01 Roth, Stefan; Singh, Vikramjeet; Tiedt, Steffen; Schindler, Lisa; Huber, Georg; Geerlof, Arie; Antoine, Daniel J.; Anfray, Antoine; Orset, Cyrille; Gauberti, Maxime; Fournier, Antoine; Holdt, Lesca M.; Harris, Helena Erlandsson; Engelhardt, Britta; Bianchi, Marco E.; Vivien, Denis; Haffner, Christof; Bernhagen, Jürgen; Dichgans, Martin; Liesz, Arthur
CD4+ T cells from IPEX patients convert into functional and stable regulatory T cells by FOXP3 gene transfer
2013-01-01 Passerini, L; Rossi Mel, E; Sartirana, C; Fousteri, G; Bondanza, Attilio; Naldini, Luigi; Roncarolo, MARIA GRAZIA; Bacchetta, R.
CD8 cis-targeted IL-2 drives potent antiviral activity against hepatitis B virus
2024-01-01 Andreata, Francesco; Moynihan, Kelly D.; Fumagalli, Valeria; Di Lucia, Pietro; Pappas, Danielle C.; Kawashima, Keigo; Ni, Irene; Bessette, Paul H.; Perucchini, Chiara; Bono, Elisa; Giustini, Leonardo; Nguyen, Henry C.; Chin, S. Michael; Yeung, Yik Andy; Gibbs, Craig S.; Djuretic, Ivana; Iannacone, Matteo
Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies
2022-01-01 Greco, B.; Malacarne, V.; Degirardi, F.; Scotti, G. M.; Manfredi, F.; Angelino, E.; Sirini, C.; Camisa, B.; Falcone, L.; Moresco, M. A.; Paolella, K.; Di Bono, M.; Norata, R.; Sanvito, F.; Arcangeli, S.; Doglioni, C.; Ciceri, F.; Bonini, C.; Graziani, A.; Bondanza, A.; Casucci, M.
Erratum: Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory (Science Translational Medicine (2015) 7:319 (319er9))
2015-01-01 Oliveira, G.; Ruggiero, E.; Stanghellini, M. T. L.; Cieri, N.; D'Agostino, M.; Fronza, R.; Lulay, C.; Dionisio, F.; Mastaglio, S.; Greco, R.; Peccatori, J.; Aiuti, Alessandro; Ambrosi, Alessandro; Biasco, L.; Bondanza, Attilio; Lambiase, A.; Traversari, C.; Vago, L.; Von Kalle, C.; Schmidt, M.; Bordignon, Claudio; Ciceri, Fabio; Bonini, MARIA CHIARA
Genetic engineering of hematopoiesis for targeted IFN-α delivery inhibits breast cancer progression
2014-01-01 Escobar, G; Moi, D; Ranghetti, A; Ozkal Baydin, P; Squadrito, Ml; Kajaste Rudnitski, A; Bondanza, Attilio; Gentner, B; De Palma, M; Mazzieri, R; Naldini, Luigi
Hematopoietic stem cell transplantation in its 60s: A platform for cellular therapies
2018-01-01 Chabannon, Christian; Kubal, Jurgen; Bondanza, Attilio; Dazzi, Francesco; Pedrazzoli, Paolo; Toubert, Antoine; Ruggeri, Annalisa; Fleischhauer, Katharina; Bonini, Chiara
Identification of hematopoietic stem cell-specific miRNAs enables gene therapy of globoid cell leukodystrophy.
2010-01-01 Gentner, B; Visigalli, I; Hiramatsu, H; Lechman, E; Ungari, S; Giustacchini, A; Schira, G; Amendola, M; Quattrini, A; Martino, S; Orlacchio, A; Dick, Je; Biffi, A; Naldini, Luigi
In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells
2015-01-01 Biasco, L; Scala, S; Basso, Ricci L; Dionisio, F; Baricordi, C; Calabria, A; Giannelli, S; Cieri, N; Barzaghi, F; Pajno, R; Al-Mousa, H; Scarselli, A; Cancrini, C; Bordignon, C; Roncarolo, M G; Montini, E; Bonini, C; Aiuti, A
Inhibition of diacylglycerol kinase alpha restores restimulation-induced cell death and reduces immunopathology in XLP-1
2016-01-01 Ruffo, E; Malacarne, V; Larsen, S; Das, R; Patrussi, L; Wulfing, C; Biskup, C; Kapnick, M; Verbist, K; Tedrick, P; Schwartzberg, P; Baldari, T; Rubio, I; Nichols, K; Snow, A; Baldanzi, G; Graziani, Andrea
Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs
2015-01-01 Akbarpour, M; Goudy, Ks; Cantore, A; Russo, F; Sanvito, F; Naldini, L; Annoni, A; Roncarolo, Mg
Liver-directed lentiviral gene therapy in a dog model of hemophilia B
2015-01-01 Cantore, A; Ranzani, M; Bartholomae, Cc; Volpin, M; Valle, Pd; Sanvito, F; Sergi, Ls; Gallina, P; Benedicenti, F; Bellinger, D; Raymer, R; Merricks, E; Bellintani, F; Martin, S; Doglioni, Claudio; D'Angelo, A; Vandendriessche, T; Chuah, Mk; Schmidt, M; Nichols, T; Montini, E; Naldini, Luigi
A multimodality test to guide the management of patients with a pancreatic cyst
2019-01-01 Springer, Simeon; Masica, David L; Dal Molin, Marco; Douville, Christopher; Thoburn, Christopher J; Afsari, Bahman; Li, Lu; Cohen, Joshua D; Thompson, Elizabeth; Allen, Peter J; Klimstra, David S; Schattner, Mark A; Schmidt, C Max; Yip-Schneider, Michele; Simpson, Rachel E; Fernandez-Del Castillo, Carlos; Mino-Kenudson, Mari; Brugge, William; Brand, Randall E; Singhi, Aatur D; Scarpa, Aldo; Lawlor, Rita; Salvia, Roberto; Zamboni, Giuseppe; Hong, Seung-Mo; Hwang, Dae Wook; Jang, Jin-Young; Kwon, Wooil; Swan, Niall; Geoghegan, Justin; Falconi, Massimo; Crippa, Stefano; Doglioni, Claudio; Paulino, Jorge; Schulick, Richard D; Edil, Barish H; Park, Walter; Yachida, Shinichi; Hijioka, Susumu; van Hooft, Jeanin; He, Jin; Weiss, Matthew J; Burkhart, Richard; Makary, Martin; Canto, Marcia I; Goggins, Michael G; Ptak, Janine; Dobbyn, Lisa; Schaefer, Joy; Sillman, Natalie; Popoli, Maria; Klein, Alison P; Tomasetti, Cristian; Karchin, Rachel; Papadopoulos, Nickolas; Kinzler, Kenneth W; Vogelstein, Bert; Wolfgang, Christopher L; Hruban, Ralph H; Lennon, Anne Marie
Oncogenic JAK2V617Fcauses PD-L1 expression, mediating immune escape in myeloproliferative neoplasms
2018-01-01 Prestipino, Alessandro; Emhardt, Alica J; Aumann, Konrad; O'Sullivan, David; Gorantla, Sivahari P; Duquesne, Sandra; Melchinger, Wolfgang; Braun, Lukas; Vuckovic, Slavica; Boerries, Melanie; Busch, Hauke; Halbach, Sebastian; Pennisi, Sandra; Poggio, Teresa; Apostolova, Petya; Veratti, Pia; Hettich, Michael; Niedermann, Gabriele; Bartholomä, Mark; Shoumariyeh, Khalid; Jutzi, Jonas S; Wehrle, Julius; Dierks, Christine; Becker, Heiko; Schmitt-Graeff, Annette; Follo, Marie; Pfeifer, Dietmar; Rohr, Jan; Fuchs, Sebastian; Ehl, Stephan; Hartl, Frederike A; Minguet, Susana; Miething, Cornelius; Heidel, Florian H; Kröger, Nicolaus; Triviai, Ioanna; Brummer, Tilman; Finke, Jürgen; Illert, Anna L; Ruggiero, Eliana; Bonini, Chiara; Duyster, Justus; Pahl, Heike L; Lane, Steven W; Hill, Geoffrey R; Blazar, Bruce R; von Bubnoff, Nikolas; Pearce, Erika L; Zeiser, Robert
Phagocytosis-shielded lentiviral vectors improve liver gene therapy in nonhuman primates
2019-01-01 Milani, M.; Annoni, A.; Moalli, F.; Liu, T.; Cesana, D.; Calabria, A.; Bartolaccini, S.; Biffi, M.; Russo, F.; Visigalli, I.; Raimondi, A.; Patarroyo-White, S.; Drager, D.; Cristofori, P.; Ayuso, E.; Montini, E.; Peters, R.; Iannacone, M.; Cantore, A.; Naldini, L.
Platelet microparticles sustain autophagy-associated activation of neutrophils in systemic sclerosis
2018-01-01 Maugeri, Norma; Capobianco, Annalisa; Rovere-Querini, Patrizia; Ramirez, Giuseppe A.; Tombetti, Enrico; Della Valle, Patrizia; Monno, Antonella; D'Alberti, Valentina; Gasparri, Anna Maria; Franchini, Stefano; D'Angelo, Armando; Bianchi, Marco E.; Manfredi, Angelo A.
Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1
2017-01-01 Schiroli, Giulia; Ferrari, Samuele; Conway, Anthony; Jacob, Aurelien; Capo, Valentina; Albano, Luisa; Plati, Tiziana; Castiello, Maria C.; Sanvito, Francesca; Gennery, Andrew R.; Bovolenta, Chiara; Palchaudhuri, Rahul; Scadden, David T.; Holmes, Michael C.; Villa, Anna; Sitia, Giovanni; Lombardo, Angelo; Genovese, Pietro; Naldini, Luigi
Rebalancing expression of HMGB1 redox isoforms to counteract muscular dystrophy
2021-01-01 Careccia, G.; Saclier, M.; Tirone, M.; Ruggieri, E.; Principi, E.; Raffaghello, L.; Torchio, S.; Recchia, D.; Canepari, M.; Gorzanelli, A.; Ferrara, M.; Castellani, P.; Rubartelli, A.; Rovere-Querini, P.; Casalgrandi, M.; Preti, A.; Lorenzetti, I.; Bruno, C.; Bottinelli, R.; Brunelli, S.; Previtali, S. C.; Bianchi, M. E.; Messina, G.; Venereau, E.
Therapeutic liver repopulation by transient acetaminophen selection of gene-modified hepatocytes
2021-01-01 Vonada, A.; Tiyaboonchai, A.; Nygaard, S.; Posey, J.; Peters, A. M.; Winn, S. R.; Cantore, A.; Naldini, L.; Harding, C. O.; Grompe, M.
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| Adducin and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin. Part 2: Clinical Studies | 1-gen-2010 | Lanzani, C; Citterio, L; Glorioso, N; Manunta, Paolo; Tripodi, G; Salvi, E; DELLI CARPINI, S; Ferrandi, M; Messaggio, E; Staessen, Ja; Cusi, D; Macciardi, F; Argiolas, G; Valentini, G; Ferrari, P; BIANCHI G., also on behalf of OASIS HT Investigators | |
| Brain-released alarmins and stress response synergize in accelerating atherosclerosis progression after stroke | 1-gen-2018 | Roth, Stefan; Singh, Vikramjeet; Tiedt, Steffen; Schindler, Lisa; Huber, Georg; Geerlof, Arie; Antoine, Daniel J.; Anfray, Antoine; Orset, Cyrille; Gauberti, Maxime; Fournier, Antoine; Holdt, Lesca M.; Harris, Helena Erlandsson; Engelhardt, Britta; Bianchi, Marco E.; Vivien, Denis; Haffner, Christof; Bernhagen, Jürgen; Dichgans, Martin; Liesz, Arthur | |
| CD4+ T cells from IPEX patients convert into functional and stable regulatory T cells by FOXP3 gene transfer | 1-gen-2013 | Passerini, L; Rossi Mel, E; Sartirana, C; Fousteri, G; Bondanza, Attilio; Naldini, Luigi; Roncarolo, MARIA GRAZIA; Bacchetta, R. | |
| CD8 cis-targeted IL-2 drives potent antiviral activity against hepatitis B virus | 1-gen-2024 | Andreata, Francesco; Moynihan, Kelly D.; Fumagalli, Valeria; Di Lucia, Pietro; Pappas, Danielle C.; Kawashima, Keigo; Ni, Irene; Bessette, Paul H.; Perucchini, Chiara; Bono, Elisa; Giustini, Leonardo; Nguyen, Henry C.; Chin, S. Michael; Yeung, Yik Andy; Gibbs, Craig S.; Djuretic, Ivana; Iannacone, Matteo | |
| Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies | 1-gen-2022 | Greco, B.; Malacarne, V.; Degirardi, F.; Scotti, G. M.; Manfredi, F.; Angelino, E.; Sirini, C.; Camisa, B.; Falcone, L.; Moresco, M. A.; Paolella, K.; Di Bono, M.; Norata, R.; Sanvito, F.; Arcangeli, S.; Doglioni, C.; Ciceri, F.; Bonini, C.; Graziani, A.; Bondanza, A.; Casucci, M. | |
| Erratum: Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory (Science Translational Medicine (2015) 7:319 (319er9)) | 1-gen-2015 | Oliveira, G.; Ruggiero, E.; Stanghellini, M. T. L.; Cieri, N.; D'Agostino, M.; Fronza, R.; Lulay, C.; Dionisio, F.; Mastaglio, S.; Greco, R.; Peccatori, J.; Aiuti, Alessandro; Ambrosi, Alessandro; Biasco, L.; Bondanza, Attilio; Lambiase, A.; Traversari, C.; Vago, L.; Von Kalle, C.; Schmidt, M.; Bordignon, Claudio; Ciceri, Fabio; Bonini, MARIA CHIARA | |
| Genetic engineering of hematopoiesis for targeted IFN-α delivery inhibits breast cancer progression | 1-gen-2014 | Escobar, G; Moi, D; Ranghetti, A; Ozkal Baydin, P; Squadrito, Ml; Kajaste Rudnitski, A; Bondanza, Attilio; Gentner, B; De Palma, M; Mazzieri, R; Naldini, Luigi | |
| Hematopoietic stem cell transplantation in its 60s: A platform for cellular therapies | 1-gen-2018 | Chabannon, Christian; Kubal, Jurgen; Bondanza, Attilio; Dazzi, Francesco; Pedrazzoli, Paolo; Toubert, Antoine; Ruggeri, Annalisa; Fleischhauer, Katharina; Bonini, Chiara | |
| Identification of hematopoietic stem cell-specific miRNAs enables gene therapy of globoid cell leukodystrophy. | 1-gen-2010 | Gentner, B; Visigalli, I; Hiramatsu, H; Lechman, E; Ungari, S; Giustacchini, A; Schira, G; Amendola, M; Quattrini, A; Martino, S; Orlacchio, A; Dick, Je; Biffi, A; Naldini, Luigi | |
| In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells | 1-gen-2015 | Biasco, L; Scala, S; Basso, Ricci L; Dionisio, F; Baricordi, C; Calabria, A; Giannelli, S; Cieri, N; Barzaghi, F; Pajno, R; Al-Mousa, H; Scarselli, A; Cancrini, C; Bordignon, C; Roncarolo, M G; Montini, E; Bonini, C; Aiuti, A | |
| Inhibition of diacylglycerol kinase alpha restores restimulation-induced cell death and reduces immunopathology in XLP-1 | 1-gen-2016 | Ruffo, E; Malacarne, V; Larsen, S; Das, R; Patrussi, L; Wulfing, C; Biskup, C; Kapnick, M; Verbist, K; Tedrick, P; Schwartzberg, P; Baldari, T; Rubio, I; Nichols, K; Snow, A; Baldanzi, G; Graziani, Andrea | |
| Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs | 1-gen-2015 | Akbarpour, M; Goudy, Ks; Cantore, A; Russo, F; Sanvito, F; Naldini, L; Annoni, A; Roncarolo, Mg | |
| Liver-directed lentiviral gene therapy in a dog model of hemophilia B | 1-gen-2015 | Cantore, A; Ranzani, M; Bartholomae, Cc; Volpin, M; Valle, Pd; Sanvito, F; Sergi, Ls; Gallina, P; Benedicenti, F; Bellinger, D; Raymer, R; Merricks, E; Bellintani, F; Martin, S; Doglioni, Claudio; D'Angelo, A; Vandendriessche, T; Chuah, Mk; Schmidt, M; Nichols, T; Montini, E; Naldini, Luigi | |
| A multimodality test to guide the management of patients with a pancreatic cyst | 1-gen-2019 | Springer, Simeon; Masica, David L; Dal Molin, Marco; Douville, Christopher; Thoburn, Christopher J; Afsari, Bahman; Li, Lu; Cohen, Joshua D; Thompson, Elizabeth; Allen, Peter J; Klimstra, David S; Schattner, Mark A; Schmidt, C Max; Yip-Schneider, Michele; Simpson, Rachel E; Fernandez-Del Castillo, Carlos; Mino-Kenudson, Mari; Brugge, William; Brand, Randall E; Singhi, Aatur D; Scarpa, Aldo; Lawlor, Rita; Salvia, Roberto; Zamboni, Giuseppe; Hong, Seung-Mo; Hwang, Dae Wook; Jang, Jin-Young; Kwon, Wooil; Swan, Niall; Geoghegan, Justin; Falconi, Massimo; Crippa, Stefano; Doglioni, Claudio; Paulino, Jorge; Schulick, Richard D; Edil, Barish H; Park, Walter; Yachida, Shinichi; Hijioka, Susumu; van Hooft, Jeanin; He, Jin; Weiss, Matthew J; Burkhart, Richard; Makary, Martin; Canto, Marcia I; Goggins, Michael G; Ptak, Janine; Dobbyn, Lisa; Schaefer, Joy; Sillman, Natalie; Popoli, Maria; Klein, Alison P; Tomasetti, Cristian; Karchin, Rachel; Papadopoulos, Nickolas; Kinzler, Kenneth W; Vogelstein, Bert; Wolfgang, Christopher L; Hruban, Ralph H; Lennon, Anne Marie | |
| Oncogenic JAK2V617Fcauses PD-L1 expression, mediating immune escape in myeloproliferative neoplasms | 1-gen-2018 | Prestipino, Alessandro; Emhardt, Alica J; Aumann, Konrad; O'Sullivan, David; Gorantla, Sivahari P; Duquesne, Sandra; Melchinger, Wolfgang; Braun, Lukas; Vuckovic, Slavica; Boerries, Melanie; Busch, Hauke; Halbach, Sebastian; Pennisi, Sandra; Poggio, Teresa; Apostolova, Petya; Veratti, Pia; Hettich, Michael; Niedermann, Gabriele; Bartholomä, Mark; Shoumariyeh, Khalid; Jutzi, Jonas S; Wehrle, Julius; Dierks, Christine; Becker, Heiko; Schmitt-Graeff, Annette; Follo, Marie; Pfeifer, Dietmar; Rohr, Jan; Fuchs, Sebastian; Ehl, Stephan; Hartl, Frederike A; Minguet, Susana; Miething, Cornelius; Heidel, Florian H; Kröger, Nicolaus; Triviai, Ioanna; Brummer, Tilman; Finke, Jürgen; Illert, Anna L; Ruggiero, Eliana; Bonini, Chiara; Duyster, Justus; Pahl, Heike L; Lane, Steven W; Hill, Geoffrey R; Blazar, Bruce R; von Bubnoff, Nikolas; Pearce, Erika L; Zeiser, Robert | |
| Phagocytosis-shielded lentiviral vectors improve liver gene therapy in nonhuman primates | 1-gen-2019 | Milani, M.; Annoni, A.; Moalli, F.; Liu, T.; Cesana, D.; Calabria, A.; Bartolaccini, S.; Biffi, M.; Russo, F.; Visigalli, I.; Raimondi, A.; Patarroyo-White, S.; Drager, D.; Cristofori, P.; Ayuso, E.; Montini, E.; Peters, R.; Iannacone, M.; Cantore, A.; Naldini, L. | |
| Platelet microparticles sustain autophagy-associated activation of neutrophils in systemic sclerosis | 1-gen-2018 | Maugeri, Norma; Capobianco, Annalisa; Rovere-Querini, Patrizia; Ramirez, Giuseppe A.; Tombetti, Enrico; Della Valle, Patrizia; Monno, Antonella; D'Alberti, Valentina; Gasparri, Anna Maria; Franchini, Stefano; D'Angelo, Armando; Bianchi, Marco E.; Manfredi, Angelo A. | |
| Preclinical modeling highlights the therapeutic potential of hematopoietic stem cell gene editing for correction of SCID-X1 | 1-gen-2017 | Schiroli, Giulia; Ferrari, Samuele; Conway, Anthony; Jacob, Aurelien; Capo, Valentina; Albano, Luisa; Plati, Tiziana; Castiello, Maria C.; Sanvito, Francesca; Gennery, Andrew R.; Bovolenta, Chiara; Palchaudhuri, Rahul; Scadden, David T.; Holmes, Michael C.; Villa, Anna; Sitia, Giovanni; Lombardo, Angelo; Genovese, Pietro; Naldini, Luigi | |
| Rebalancing expression of HMGB1 redox isoforms to counteract muscular dystrophy | 1-gen-2021 | Careccia, G.; Saclier, M.; Tirone, M.; Ruggieri, E.; Principi, E.; Raffaghello, L.; Torchio, S.; Recchia, D.; Canepari, M.; Gorzanelli, A.; Ferrara, M.; Castellani, P.; Rubartelli, A.; Rovere-Querini, P.; Casalgrandi, M.; Preti, A.; Lorenzetti, I.; Bruno, C.; Bottinelli, R.; Brunelli, S.; Previtali, S. C.; Bianchi, M. E.; Messina, G.; Venereau, E. | |
| Therapeutic liver repopulation by transient acetaminophen selection of gene-modified hepatocytes | 1-gen-2021 | Vonada, A.; Tiyaboonchai, A.; Nygaard, S.; Posey, J.; Peters, A. M.; Winn, S. R.; Cantore, A.; Naldini, L.; Harding, C. O.; Grompe, M. |
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