IRIS
RONCAROLO, MARIA GRAZIA
 Distribuzione geografica
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Continente #
AS - Asia 6.538
EU - Europa 5.572
NA - Nord America 4.722
SA - Sud America 1.654
Continente sconosciuto - Info sul continente non disponibili 141
AF - Africa 112
OC - Oceania 24
Totale 18.763
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Nazione #
US - Stati Uniti d'America 4.506
RU - Federazione Russa 3.107
SG - Singapore 2.200
CN - Cina 2.192
BR - Brasile 1.352
SE - Svezia 888
HK - Hong Kong 839
VN - Vietnam 556
IT - Italia 545
FR - Francia 312
BD - Bangladesh 189
DE - Germania 183
IN - India 139
GB - Regno Unito 120
AR - Argentina 115
CA - Canada 102
FI - Finlandia 89
ID - Indonesia 61
AT - Austria 59
EC - Ecuador 56
MX - Messico 55
IQ - Iraq 50
JP - Giappone 50
NL - Olanda 48
IE - Irlanda 42
ES - Italia 41
PL - Polonia 36
TR - Turchia 35
CO - Colombia 31
MY - Malesia 28
ZA - Sudafrica 28
CL - Cile 27
PK - Pakistan 26
PY - Paraguay 25
KR - Corea 24
AU - Australia 23
UA - Ucraina 23
VE - Venezuela 22
SA - Arabia Saudita 18
TN - Tunisia 17
AE - Emirati Arabi Uniti 16
MA - Marocco 16
PH - Filippine 16
JM - Giamaica 14
UZ - Uzbekistan 13
UY - Uruguay 11
DZ - Algeria 10
KE - Kenya 10
CH - Svizzera 8
CR - Costa Rica 8
EG - Egitto 8
ET - Etiopia 8
NP - Nepal 8
RO - Romania 8
JO - Giordania 7
KZ - Kazakistan 7
LT - Lituania 7
PE - Perù 7
PT - Portogallo 7
BA - Bosnia-Erzegovina 6
BB - Barbados 6
BO - Bolivia 6
GR - Grecia 6
IL - Israele 6
KW - Kuwait 6
LB - Libano 6
TT - Trinidad e Tobago 6
AL - Albania 5
AZ - Azerbaigian 5
BE - Belgio 5
DO - Repubblica Dominicana 5
LV - Lettonia 5
TH - Thailandia 5
BG - Bulgaria 4
BH - Bahrain 4
GE - Georgia 4
IR - Iran 4
NI - Nicaragua 4
PS - Palestinian Territory 4
SK - Slovacchia (Repubblica Slovacca) 4
SY - Repubblica araba siriana 4
GT - Guatemala 3
HN - Honduras 3
HU - Ungheria 3
LA - Repubblica Popolare Democratica del Laos 3
SV - El Salvador 3
AM - Armenia 2
BY - Bielorussia 2
CG - Congo 2
CZ - Repubblica Ceca 2
MD - Moldavia 2
MM - Myanmar 2
NG - Nigeria 2
OM - Oman 2
PA - Panama 2
PR - Porto Rico 2
RS - Serbia 2
SN - Senegal 2
TW - Taiwan 2
AO - Angola 1
Totale 18.600
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Città #
Singapore 844
Hong Kong 819
Moscow 686
San Jose 611
Ashburn 567
Dallas 507
Shanghai 396
Council Bluffs 305
Hefei 304
Lawrence 292
Princeton 292
Lauterbourg 266
Ho Chi Minh City 206
Beijing 187
New York 155
Santa Clara 138
Hanoi 123
São Paulo 113
Milan 107
Los Angeles 95
Helsinki 77
Nuremberg 60
The Dalles 47
Rome 45
Rio de Janeiro 43
Boardman 41
Phoenix 39
Dublin 38
Brooklyn 37
Pune 36
Belo Horizonte 35
Orem 33
Montreal 32
Seattle 32
Tokyo 32
Warsaw 32
Washington 32
Brasília 31
Chicago 31
Vienna 31
Guangzhou 30
Da Nang 28
Columbus 25
London 25
Shenzhen 24
Toronto 24
Boston 23
Curitiba 22
Haiphong 21
Chennai 20
Denver 20
Johannesburg 20
Munich 20
Naples 20
Porto Alegre 20
Salvador 20
Baghdad 19
Houston 19
Dhaka 18
Buffalo 17
Guayaquil 17
Jakarta 17
Quito 17
Biên Hòa 16
Santiago 16
Ankara 15
Atlanta 15
Campinas 15
Hangzhou 15
Mumbai 15
Philadelphia 15
Poplar 15
Stockholm 15
Tianjin 15
Kuala Lumpur 14
Mexico City 14
Guarulhos 13
Miami 13
Paris 13
San Rafael 13
Charlotte 12
Frankfurt am Main 12
Ribeirão Preto 12
San Francisco 12
Tashkent 12
Changsha 11
Las Vegas 11
Santo André 11
Sorocaba 11
Sydney 11
Caxias do Sul 10
Genoa 10
Goiânia 10
Ha Long 10
Kingston 10
Lahore 10
Madrid 10
Montevideo 10
Riyadh 10
Turku 10
Totale 8.745
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Nome #
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy 432
Loss of mismatched HLA in leukemia after stem-cell transplantation 219
INTERLEUKIN-10 (IL-10) AND VIRAL-IL-10 STRONGLY REDUCE ANTIGEN-SPECIFIC HUMAN T-CELL PROLIFERATION BY DIMINISHING THE ANTIGEN-PRESENTING CAPACITY OF MONOCYTES VIA DOWN-REGULATION OF CLASS-II MAJOR HISTOCOMPATIBILITY COMPLEX EXPRESSION 190
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors 147
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis 142
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID 138
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients 130
Bone marrow as source of hematopoietic stem cells for human gene therapy of beta thalassemia 126
Pruritus characteristics in a large Italian cohort of psoriatic patients 122
A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome 119
ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency 119
Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study 116
Absence of VOD in paediatric thalassaemic HSCT recipients using defibrotide prophylaxis and intravenous Busulphan 115
Abnormalities of acid-base balance and predisposition to metabolic acidosis in Metachromatic Leukodystrophy patients 114
Induction of isotype switching and Ig production by CD5+ and CD10+ human fetal B cells 113
Gene therapy for immunodeficiency due to adenosine deaminase deficiency 112
Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk. 112
null 112
A transgenic model to analyze the immunoregulatory role of IL-10 secreted by antigen-presenting cells 111
A SCID PATIENT RECONSTITUTED WITH HLA-INCOMPATIBLE FETAL STEM-CELLS AS A MODEL FOR STUDYING TRANSPLANTATION TOLERANCE 109
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects 107
WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells 105
An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells 104
High incidence of severe cyclosporine neurotoxicity in children affected by haemoglobinopaties undergoing myeloablative haematopoietic stem cell transplantation: early diagnosis and prompt intervention ameliorates neurological outcome 104
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors 101
Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production 101
A proportion of patients with lymphoma may harbor mutations of the perforin gene 100
In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance 95
Health related quality of life in Middle Eastern children with beta-thalassemia 92
ANTI-SCID MOUSE REACTIVITY SHAPES THE HUMAN CD4(+) T-CELL REPERTOIRE IN HU-P8L-SCID CHIMERAS 92
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans 91
Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T cells 91
Correction of ß-thalassemia major by gene transfer in hematopoietic progenitors of pediatric patients 91
Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs 90
A novel function of FOXP3 in humans: intrinsic regulation of conventional T cells 89
Administration of Flk2/Flt3 ligand induces expansion of human high-proliferative potential colony-forming cells in the SCID-hu mouse 87
Beneficial autoimmunity in Type 1 diabetes mellitus 86
The quality of life of children and adolescents with X-linked agammaglobulinemia 85
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy 85
Analysis of galactocerebrosidase activity in the mouse brain by a new histological staining method 84
Advanced cell-based therapies for the treatment of primary immunodeficiency (Cell-PID) 83
Altered T-cell receptor +CD28- mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-beta-treated alloreactive T cells that do not induce graft-versus-host disease 80
Treatment with rapamycin can restore regulatory T-cell function in IPEX patients 80
Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice 79
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome 78
Stability of human rapamycin-expanded CD4(+)CD25(+) T regulatory cells 78
UNIQUE CYTOKINE PRODUCTION PROFILE OF ANERGIC HUMAN T-CELLS IN SCID-HU MICE AFTER STAPHYLOCOCCAL-ENTEROTOXIN-B ADMINISTRATION 77
T-CELL REPERTOIRE AND TOLERANCE AFTER FETAL STEM-CELL TRANSPLANTATION 77
INTERLEUKIN-10 77
Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial 77
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning 75
Immunological outcome in haploicentical-HSC transplanted patients treated with IL-10-anergizec donor T Cells 73
Efficacy of gene therapy for Wiskott-Aldrich syndrome using a WAS promoter/cDNA-containing lentiviral vector and nonlethal irradiation 72
The capacity of interleukin-4 to induce in vitro IgE synthesis by B cells of patients with common variable immunodeficiency 72
Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation 71
Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway 70
Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25(+)CD4(+) Tr cells 70
Isolation and expression of human cytokine synthesis inhibitory factor (CSIF/IL-10) cDNA clones: Homology to Epstein-Barr virus open reading frame BCRF1 70
Clinical improvement and normalized Th1 cytokine profile in early and long-term Interferon-alpha treatment in a suspected case of Hyper-IgE Syndrome 70
IgE content of commercial intravenous IgG preparations 69
Enforced IL-10 Expression Confers Type 1 Regulatory T Cell (Tr1) Phenotype and Function to Human CD4(+) T Cells 69
Revertant T lymphocytes in a patient with Wiskott-Aldrich syndrome: Analysis of function and distribution in lymphoid organs 69
Rapamycin prevents and breaks the anti-CD3-induced tolerance in NOD mice 68
Antigen-specific cytotoxic T cells mediate human fetal pancreas allograft rejection in SCID-hu mice 68
Recombinant human interleukin 10 suppresses gliadin dependent T cell activation in ex vivo cultured coeliac intestinal mucosa 68
In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases 68
HUMAN HEMATOPOIETIC-CELLS AND THYMIC EPITHELIAL-CELLS INDUCE TOLERANCE VIA DIFFERENT MECHANISMS IN THE SCID-HU MOUSE THYMUS 67
STAT5-signaling cytokines regulate the expression of FOXP3 in CD4(+)CD25(+) regulatory T cells and CD4(+)CD25(-) effector T cells 67
The cellular and molecular mechanisms of immuno-suppression by human type 1 regulatory T cells 67
Molecular and functional characterization of allogantigen-specific anergic T cells suitable for cell therapy 67
Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency 67
Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice 67
Human T-and B-cell functions in SCID-hu mice 67
IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells 66
CD4+ T cells from IPEX patients convert into functional and stable regulatory T cells by FOXP3 gene transfer 66
Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans 66
Gene correction for SCID-X1 in long-term hematopoietic stem cells 66
Genomic organization of the human T-cell antigen-receptor α/δ locus 65
The presence of normal EBV-specific, HLA-restricted cytotoxic activity in two XLP patients with hypogammaglobulinemia. 65
REGULATION OF HUMAN IGE SYNTHESIS - THE ROLE OF CD4+ AND CD8+ T-CELLS AND THE INHIBITORY EFFECTS OF INTEREFON-ALPHA 65
Rapamycin selectively expands CD4(+)CD25(+)FoxP3(+) regulatory T cells 64
Evidence for long-term efficacy and safety of gene therapy for Wiskott Aldrich syndrome in preclinical models 64
Frequency and targeted detection of HLA-DPB1 T cell epitope disparities relevant in unrelated hematopoietic stem cell transplantation 64
PROGRESS IN THE EX-VIVO EXPANSION OF HEMATOPOIETIC PROGENITORS 63
Autoreactive T cell clones specific for class I and class II HLA antigens isolated from a human chimera 63
Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity 63
In vivo administration of lentiviral vectors triggers a type I interferon response that restricts hepatocyte gene transfer and promotes vector clearance 63
Integration profile of retroviral vector in gene therapy treated patients is cell-specific according to gene expression and chromatin conformation of target cell 63
HLA-HAPLOIDENTICAL UMBILICAL-CORD BLOOD STEM-CELL TRANSPLANTATION IN A CHILD WITH ADVANCED LEUKEMIA - CLINICAL OUTCOME AND ANALYSIS OF HEMATOPOIETIC RECOVERY 63
Temporal, quantitative, and functional characteristics of single-KIR-positive alloreactive natural killer cell recovery account for impaired graft-versus-leukemia activity after haploidentical hematopoietic stem cell transplantation 63
Gene therapy for adenosine deaminase deficiency 62
DO HUMAN TH1 AND TH2 CD4+ CLONES EXIST 62
Gene Therapy for Adenosine Deaminase Deficiency: A Comprehensive Evaluation of Short- and Medium-Term Safety 62
Long-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study 62
LYMPHOID AND MYELOID DIFFERENTIATION OF FETAL LIVER CD34+ LINEAGE(-) CELLS IN HUMAN THYMIC ORGAN-CULTURE 62
Regulatory T cells: prospective for clinical application in hematopoietic stem cell transplantation 61
The FLK2/FLT3 ligand synergizes with interleukin-7 in promoting stromal-cell-independent expansion and differentiation of human fetal pro-B cells in vitro 61
IL-10-Engineered Human CD4+ Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism 61
In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells 61
Ectopic FOXP3 Expression Preserves Primitive Features of Human Hematopoietic Stem Cells while Impairing Functional T Cell Differentiation 61
Totale 8.862
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Categoria #
all - tutte 131.423
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 131.423
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022174 0 0 0 83 11 6 1 7 6 52 1 7
2022/20231.599 660 370 95 5 9 148 49 75 146 13 15 14
2023/2024817 37 38 82 73 50 152 70 85 4 42 61 123
2024/20253.855 527 63 51 128 99 331 426 298 754 631 245 302
2025/202611.288 786 869 927 1.675 605 297 1.137 800 2.884 618 301 389
2026/2027963 365 598 0 0 0 0 0 0 0 0 0 0
Totale 18.763