IRIS
RONCAROLO, MARIA GRAZIA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
AS - Asia 4.934
NA - Nord America 2.622
EU - Europa 2.102
SA - Sud America 1.513
AF - Africa 86
OC - Oceania 20
Continente sconosciuto - Info sul continente non disponibili 1
Totale 11.278
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 2.508
SG - Singapore 2.049
CN - Cina 1.284
BR - Brasile 1.281
SE - Svezia 886
HK - Hong Kong 750
VN - Vietnam 387
RU - Federazione Russa 302
IT - Italia 289
DE - Germania 159
IN - India 108
AR - Argentina 95
GB - Regno Unito 90
FI - Finlandia 87
CA - Canada 61
AT - Austria 52
BD - Bangladesh 51
ID - Indonesia 48
EC - Ecuador 43
JP - Giappone 42
IE - Irlanda 41
IQ - Iraq 39
FR - Francia 35
NL - Olanda 35
MX - Messico 34
PL - Polonia 27
ZA - Sudafrica 27
TR - Turchia 24
CO - Colombia 23
ES - Italia 23
KR - Corea 23
PK - Pakistan 22
AU - Australia 19
CL - Cile 19
PY - Paraguay 19
UA - Ucraina 15
AE - Emirati Arabi Uniti 14
VE - Venezuela 14
MA - Marocco 13
SA - Arabia Saudita 11
TN - Tunisia 11
UZ - Uzbekistan 11
DZ - Algeria 9
UY - Uruguay 9
CH - Svizzera 7
EG - Egitto 7
ET - Etiopia 7
LT - Lituania 7
MY - Malesia 7
JM - Giamaica 6
KE - Kenya 6
KW - Kuwait 6
KZ - Kazakistan 6
PH - Filippine 6
PT - Portogallo 6
RO - Romania 6
AL - Albania 5
BA - Bosnia-Erzegovina 5
DO - Repubblica Dominicana 5
IL - Israele 5
LV - Lettonia 5
PE - Perù 5
AZ - Azerbaigian 4
BH - Bahrain 4
GR - Grecia 4
IR - Iran 4
LB - Libano 4
SK - Slovacchia (Repubblica Slovacca) 4
SY - Repubblica araba siriana 4
BE - Belgio 3
BG - Bulgaria 3
BO - Bolivia 3
GE - Georgia 3
JO - Giordania 3
PS - Palestinian Territory 3
BB - Barbados 2
HU - Ungheria 2
LA - Repubblica Popolare Democratica del Laos 2
NP - Nepal 2
OM - Oman 2
PA - Panama 2
TT - Trinidad e Tobago 2
AM - Armenia 1
AO - Angola 1
BN - Brunei Darussalam 1
BY - Bielorussia 1
CY - Cipro 1
EE - Estonia 1
GH - Ghana 1
GP - Guadalupe 1
GY - Guiana 1
KG - Kirghizistan 1
NA - Namibia 1
NG - Nigeria 1
NO - Norvegia 1
NZ - Nuova Zelanda 1
RS - Serbia 1
SN - Senegal 1
SR - Suriname 1
SV - El Salvador 1
Totale 11.274
Salva come PNG Salva come JPEG
Città #
Singapore 756
Hong Kong 738
Dallas 489
Shanghai 377
Ashburn 314
Hefei 303
Lawrence 292
Princeton 292
Ho Chi Minh City 156
São Paulo 108
Beijing 104
New York 100
Moscow 86
Hanoi 80
Helsinki 76
Milan 71
Los Angeles 58
Nuremberg 52
The Dalles 45
Rio de Janeiro 39
Dublin 38
Boardman 37
Pune 36
Belo Horizonte 32
Brasília 29
Tokyo 29
Washington 27
Brooklyn 26
Guangzhou 25
Vienna 25
Warsaw 25
Columbus 24
Montreal 23
Santa Clara 22
Seattle 22
London 20
Munich 20
Salvador 20
Curitiba 19
Johannesburg 19
Porto Alegre 18
Toronto 18
Baghdad 15
Haiphong 15
Jakarta 15
Shenzhen 15
Chennai 14
Guayaquil 14
Ankara 13
Campinas 13
Chicago 13
Da Nang 13
Denver 13
Dhaka 13
Hangzhou 13
San Rafael 13
Stockholm 13
Guarulhos 12
Mumbai 12
Paris 12
Poplar 12
Ribeirão Preto 12
Atlanta 11
Boston 11
Quito 11
Santo André 11
Sorocaba 11
Tashkent 11
Biên Hòa 10
Caxias do Sul 10
Changsha 10
Orem 10
Rome 10
Santiago 10
Turku 10
Goiânia 9
Ha Long 9
Houston 9
New Delhi 9
Sydney 9
São José do Rio Preto 9
Tianjin 9
Cesano Boscone 8
Council Bluffs 8
Jundiaí 8
Manaus 8
Montevideo 8
Naples 8
Phoenix 8
San Francisco 8
Seoul 8
Thái Nguyên 8
Volta Redonda 8
Asunción 7
Bauru 7
Jiaxing 7
Lahore 7
Monza 7
Osasco 7
Philadelphia 7
Totale 5.691
Salva come PNG Salva come JPEG
Nome #
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy 326
INTERLEUKIN-10 (IL-10) AND VIRAL-IL-10 STRONGLY REDUCE ANTIGEN-SPECIFIC HUMAN T-CELL PROLIFERATION BY DIMINISHING THE ANTIGEN-PRESENTING CAPACITY OF MONOCYTES VIA DOWN-REGULATION OF CLASS-II MAJOR HISTOCOMPATIBILITY COMPLEX EXPRESSION 153
Loss of mismatched HLA in leukemia after stem-cell transplantation 133
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors 106
Bone marrow as source of hematopoietic stem cells for human gene therapy of beta thalassemia 82
Erratum: IL-10-Engineered Human CD4+ Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism (Molecular Therapy (2017) 25(10) (2254–2269), (S1525001617303143), (10.1016/j.ymthe.2017.06.029)) 82
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis 78
A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome 77
Gene therapy for immunodeficiency due to adenosine deaminase deficiency 77
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID 76
Pruritus characteristics in a large Italian cohort of psoriatic patients 74
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients 74
ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency 71
Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production 71
An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells 70
Abnormalities of acid-base balance and predisposition to metabolic acidosis in Metachromatic Leukodystrophy patients 68
A proportion of patients with lymphoma may harbor mutations of the perforin gene 67
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors 66
Beneficial autoimmunity in Type 1 diabetes mellitus 65
Absence of VOD in paediatric thalassaemic HSCT recipients using defibrotide prophylaxis and intravenous Busulphan 65
Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk. 64
A SCID PATIENT RECONSTITUTED WITH HLA-INCOMPATIBLE FETAL STEM-CELLS AS A MODEL FOR STUDYING TRANSPLANTATION TOLERANCE 63
A transgenic model to analyze the immunoregulatory role of IL-10 secreted by antigen-presenting cells 63
Analysis of galactocerebrosidase activity in the mouse brain by a new histological staining method 60
ANTI-SCID MOUSE REACTIVITY SHAPES THE HUMAN CD4(+) T-CELL REPERTOIRE IN HU-P8L-SCID CHIMERAS 60
In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance 59
WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells 59
High incidence of severe cyclosporine neurotoxicity in children affected by haemoglobinopaties undergoing myeloablative haematopoietic stem cell transplantation: early diagnosis and prompt intervention ameliorates neurological outcome 59
Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T cells 58
A novel function of FOXP3 in humans: intrinsic regulation of conventional T cells 58
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy 56
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome 56
Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs 56
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects 55
Advanced cell-based therapies for the treatment of primary immunodeficiency (Cell-PID) 52
INTERLEUKIN-10 52
The quality of life of children and adolescents with X-linked agammaglobulinemia 51
UNIQUE CYTOKINE PRODUCTION PROFILE OF ANERGIC HUMAN T-CELLS IN SCID-HU MICE AFTER STAPHYLOCOCCAL-ENTEROTOXIN-B ADMINISTRATION 50
Administration of Flk2/Flt3 ligand induces expansion of human high-proliferative potential colony-forming cells in the SCID-hu mouse 50
Altered T-cell receptor +CD28- mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-beta-treated alloreactive T cells that do not induce graft-versus-host disease 50
Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice 50
Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study 50
Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial 50
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans 49
Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency 49
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning 49
Correction of ß-thalassemia major by gene transfer in hematopoietic progenitors of pediatric patients 48
T-CELL REPERTOIRE AND TOLERANCE AFTER FETAL STEM-CELL TRANSPLANTATION 47
Clinical improvement and normalized Th1 cytokine profile in early and long-term Interferon-alpha treatment in a suspected case of Hyper-IgE Syndrome 47
IL-10-Engineered Human CD4+ Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism 47
Treatment with rapamycin can restore regulatory T-cell function in IPEX patients 47
IgE content of commercial intravenous IgG preparations 45
Genomic organization of the human T-cell antigen-receptor α/δ locus 45
Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice 45
Revertant T lymphocytes in a patient with Wiskott-Aldrich syndrome: Analysis of function and distribution in lymphoid organs 44
Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway 43
Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans 43
The FLK2/FLT3 ligand synergizes with interleukin-7 in promoting stromal-cell-independent expansion and differentiation of human fetal pro-B cells in vitro 42
Preclinical safety and efficacy of human CD34(+) cells transduced with lentiviral vector for the treatment of Wiskott-Aldrich syndrome. 42
Rapamycin prevents and breaks the anti-CD3-induced tolerance in NOD mice 41
IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells 41
Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity 41
In vivo and in vitro anti-tetanus toxoid antibody production in patients with HLA-mismatched T cells following fetal liver and thymus transplantations 41
CITOCHINE E VACCINAZIONI 41
In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases 41
Induction of isotype switching and Ig production by CD5+ and CD10+ human fetal B cells 40
Recombinant human interleukin 10 suppresses gliadin dependent T cell activation in ex vivo cultured coeliac intestinal mucosa 40
Human T-and B-cell functions in SCID-hu mice 40
Type 1 T regulatory cells and their relationship with CD4+CD25+ T regulatory cells 40
Stability of human rapamycin-expanded CD4(+)CD25(+) T regulatory cells 40
CD4+ T cells from IPEX patients convert into functional and stable regulatory T cells by FOXP3 gene transfer 40
In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells 40
Efficacy of gene therapy for Wiskott-Aldrich syndrome using a WAS promoter/cDNA-containing lentiviral vector and nonlethal irradiation 39
Antigen-specific cytotoxic T cells mediate human fetal pancreas allograft rejection in SCID-hu mice 39
PROGRESS IN THE EX-VIVO EXPANSION OF HEMATOPOIETIC PROGENITORS 39
Ectopic FOXP3 Expression Preserves Primitive Features of Human Hematopoietic Stem Cells while Impairing Functional T Cell Differentiation 39
Gene correction for SCID-X1 in long-term hematopoietic stem cells 39
Regulatory T cells: prospective for clinical application in hematopoietic stem cell transplantation 38
Rapamycin selectively expands CD4(+)CD25(+)FoxP3(+) regulatory T cells 38
The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatoy cells 38
Comment on M. Guillot-Delost et al. (2008;10:834-846): Clinical-grade preparation of human natural regulatory T cells encoding the thymidine kinase suicide gene as a safety gene 38
Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement 38
Evidence for long-term efficacy and safety of gene therapy for Wiskott Aldrich syndrome in preclinical models 38
Isolation and expression of human cytokine synthesis inhibitory factor (CSIF/IL-10) cDNA clones: Homology to Epstein-Barr virus open reading frame BCRF1 38
Thymic factor therapy of viral infections in childhood 38
The capacity of interleukin-4 to induce in vitro IgE synthesis by B cells of patients with common variable immunodeficiency 38
Integration of Retroviral Vector Induces Minor Changes in the Transcriptional Activity of T Cells from ADA-SCID Patients Treated with Gene Therapy 38
Immunological outcome in haploicentical-HSC transplanted patients treated with IL-10-anergizec donor T Cells 38
Tr1 cells in allogeneic transplantations 38
LYMPHOID AND MYELOID DIFFERENTIATION OF FETAL LIVER CD34+ LINEAGE(-) CELLS IN HUMAN THYMIC ORGAN-CULTURE 38
Wild-type FOXP3 is selectively active in CD4(+)CD25(hi) regulatory T cells of healthy female carriers of different FOXP3 mutations 38
Erratum: Preclinical Safety and Efficacy of Human CD34+ Cells Transduced with Lentiviral Vector for the Treatment of Wiskott-Aldrich Syndrome (Molecular Therapy (2013) 21 (175-184) DOI:10.1038/mt.2012.23) 37
Gene therapy for adenosine deaminase deficiency 37
T- regulatory 1 cells: a novel subset of CD4+ T cells with immunoregolatory properties 37
Integration profile of retroviral vector in gene therapy treated patients is cell-specific according to gene expression and chromatin conformation of target cell 37
Molecular and functional characterization of allogantigen-specific anergic T cells suitable for cell therapy 37
Coexpression of CD49b and LAG-3 identifies human and mouse T regulatory type 1 cells 37
Immune responses in liver-directed lentiviral gene therapy 37
Second hematopoietic SCT in patients with thalassemia recurrence following rejection of the first graft 37
Genotypes and haplotypes in the 3' untranslated region of the HLA-G gene and their association with clinical outcome of hematopoietic stem cell transplantation for beta-thalassemia 37
Totale 5.480
Salva come PNG Salva come JPEG
Categoria #
all - tutte 105.455
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 105.455
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20217 0 0 0 0 0 1 3 0 0 3 0 0
2021/2022174 0 0 0 83 11 6 1 7 6 52 1 7
2022/20231.599 660 370 95 5 9 148 49 75 146 13 15 14
2023/2024817 37 38 82 73 50 152 70 85 4 42 61 123
2024/20253.855 527 63 51 128 99 331 426 298 754 631 245 302
2025/20264.901 786 869 927 1.675 605 39 0 0 0 0 0 0
Totale 11.413