IRIS
RONCAROLO, MARIA GRAZIA
 Distribuzione geografica
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Continente #
AS - Asia 6.099
EU - Europa 5.396
NA - Nord America 3.541
SA - Sud America 1.627
AF - Africa 107
OC - Oceania 23
Continente sconosciuto - Info sul continente non disponibili 2
Totale 16.795
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Nazione #
US - Stati Uniti d'America 3.398
RU - Federazione Russa 3.107
SG - Singapore 2.131
CN - Cina 2.032
BR - Brasile 1.343
SE - Svezia 888
HK - Hong Kong 808
VN - Vietnam 541
IT - Italia 399
FR - Francia 306
DE - Germania 179
IN - India 136
GB - Regno Unito 116
AR - Argentina 114
FI - Finlandia 89
CA - Canada 72
BD - Bangladesh 69
AT - Austria 59
ID - Indonesia 54
EC - Ecuador 51
IQ - Iraq 50
MX - Messico 49
JP - Giappone 47
NL - Olanda 45
IE - Irlanda 42
ES - Italia 37
PL - Polonia 34
TR - Turchia 34
ZA - Sudafrica 28
CO - Colombia 27
PK - Pakistan 26
CL - Cile 25
KR - Corea 24
PY - Paraguay 24
AU - Australia 22
UA - Ucraina 21
VE - Venezuela 18
MA - Marocco 16
PH - Filippine 16
SA - Arabia Saudita 16
TN - Tunisia 16
AE - Emirati Arabi Uniti 15
MY - Malesia 13
UZ - Uzbekistan 13
UY - Uruguay 11
DZ - Algeria 9
CH - Svizzera 8
EG - Egitto 8
ET - Etiopia 8
KE - Kenya 8
JM - Giamaica 7
JO - Giordania 7
LT - Lituania 7
PE - Perù 7
RO - Romania 7
BA - Bosnia-Erzegovina 6
GR - Grecia 6
IL - Israele 6
KW - Kuwait 6
KZ - Kazakistan 6
LB - Libano 6
PT - Portogallo 6
AL - Albania 5
AZ - Azerbaigian 5
BE - Belgio 5
BO - Bolivia 5
DO - Repubblica Dominicana 5
LV - Lettonia 5
BG - Bulgaria 4
BH - Bahrain 4
GE - Georgia 4
IR - Iran 4
PS - Palestinian Territory 4
SK - Slovacchia (Repubblica Slovacca) 4
SY - Repubblica araba siriana 4
HU - Ungheria 3
NP - Nepal 3
TH - Thailandia 3
AM - Armenia 2
BB - Barbados 2
BY - Bielorussia 2
CG - Congo 2
LA - Repubblica Popolare Democratica del Laos 2
NG - Nigeria 2
OM - Oman 2
PA - Panama 2
RS - Serbia 2
SN - Senegal 2
TT - Trinidad e Tobago 2
AO - Angola 1
BN - Brunei Darussalam 1
BQ - ???statistics.table.value.countryCode.BQ??? 1
CI - Costa d'Avorio 1
CM - Camerun 1
CR - Costa Rica 1
CY - Cipro 1
CZ - Repubblica Ceca 1
EE - Estonia 1
GA - Gabon 1
GH - Ghana 1
Totale 16.779
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Città #
Singapore 810
Hong Kong 792
Moscow 686
Ashburn 503
Dallas 489
San Jose 478
Shanghai 393
Hefei 304
Lawrence 292
Princeton 292
Lauterbourg 266
Ho Chi Minh City 203
Beijing 153
New York 126
Hanoi 119
São Paulo 113
Milan 91
Helsinki 77
Los Angeles 70
Nuremberg 60
Santa Clara 48
The Dalles 46
Rio de Janeiro 43
Boardman 38
Dublin 38
Pune 36
Belo Horizonte 34
Orem 33
Tokyo 32
Brooklyn 31
Warsaw 31
Brasília 30
Guangzhou 30
Vienna 30
Washington 29
Da Nang 28
Montreal 28
Columbus 24
London 24
Shenzhen 24
Rome 23
Curitiba 22
Seattle 22
Haiphong 20
Johannesburg 20
Munich 20
Porto Alegre 20
Salvador 20
Baghdad 19
Chennai 19
Chicago 19
Toronto 19
Denver 18
Phoenix 18
Jakarta 17
Biên Hòa 16
Guayaquil 16
Santiago 16
Ankara 15
Campinas 15
Dhaka 15
Poplar 15
Quito 15
Stockholm 15
Atlanta 14
Hangzhou 14
Houston 14
Mumbai 14
Guarulhos 13
Paris 13
San Rafael 13
Boston 12
Ribeirão Preto 12
Tashkent 12
Santo André 11
Sorocaba 11
Sydney 11
Tianjin 11
Caxias do Sul 10
Changsha 10
Council Bluffs 10
Frankfurt am Main 10
Ha Long 10
Lahore 10
Mexico City 10
Montevideo 10
San Francisco 10
Turku 10
Goiânia 9
Madrid 9
Monza 9
Naples 9
New Delhi 9
Philadelphia 9
Riyadh 9
São José do Rio Preto 9
Volta Redonda 9
Cesano Boscone 8
Charlotte 8
Genoa 8
Totale 7.788
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Nome #
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy 372
Loss of mismatched HLA in leukemia after stem-cell transplantation 182
INTERLEUKIN-10 (IL-10) AND VIRAL-IL-10 STRONGLY REDUCE ANTIGEN-SPECIFIC HUMAN T-CELL PROLIFERATION BY DIMINISHING THE ANTIGEN-PRESENTING CAPACITY OF MONOCYTES VIA DOWN-REGULATION OF CLASS-II MAJOR HISTOCOMPATIBILITY COMPLEX EXPRESSION 182
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors 134
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID 119
Pruritus characteristics in a large Italian cohort of psoriatic patients 115
ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency 111
A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome 109
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis 109
Abnormalities of acid-base balance and predisposition to metabolic acidosis in Metachromatic Leukodystrophy patients 107
Bone marrow as source of hematopoietic stem cells for human gene therapy of beta thalassemia 107
Erratum: IL-10-Engineered Human CD4+ Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism (Molecular Therapy (2017) 25(10) (2254–2269), (S1525001617303143), (10.1016/j.ymthe.2017.06.029)) 107
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients 104
Gene therapy for immunodeficiency due to adenosine deaminase deficiency 102
An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells 100
Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk. 98
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors 97
A transgenic model to analyze the immunoregulatory role of IL-10 secreted by antigen-presenting cells 96
Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production 96
Absence of VOD in paediatric thalassaemic HSCT recipients using defibrotide prophylaxis and intravenous Busulphan 96
A SCID PATIENT RECONSTITUTED WITH HLA-INCOMPATIBLE FETAL STEM-CELLS AS A MODEL FOR STUDYING TRANSPLANTATION TOLERANCE 94
A proportion of patients with lymphoma may harbor mutations of the perforin gene 93
In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance 92
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects 91
High incidence of severe cyclosporine neurotoxicity in children affected by haemoglobinopaties undergoing myeloablative haematopoietic stem cell transplantation: early diagnosis and prompt intervention ameliorates neurological outcome 90
WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells 88
Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs 87
Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T cells 86
ANTI-SCID MOUSE REACTIVITY SHAPES THE HUMAN CD4(+) T-CELL REPERTOIRE IN HU-P8L-SCID CHIMERAS 86
A novel function of FOXP3 in humans: intrinsic regulation of conventional T cells 85
Beneficial autoimmunity in Type 1 diabetes mellitus 83
Administration of Flk2/Flt3 ligand induces expansion of human high-proliferative potential colony-forming cells in the SCID-hu mouse 82
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy 82
Analysis of galactocerebrosidase activity in the mouse brain by a new histological staining method 80
Advanced cell-based therapies for the treatment of primary immunodeficiency (Cell-PID) 79
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans 78
Correction of ß-thalassemia major by gene transfer in hematopoietic progenitors of pediatric patients 78
The quality of life of children and adolescents with X-linked agammaglobulinemia 76
Altered T-cell receptor +CD28- mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-beta-treated alloreactive T cells that do not induce graft-versus-host disease 75
Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice 75
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome 74
UNIQUE CYTOKINE PRODUCTION PROFILE OF ANERGIC HUMAN T-CELLS IN SCID-HU MICE AFTER STAPHYLOCOCCAL-ENTEROTOXIN-B ADMINISTRATION 73
T-CELL REPERTOIRE AND TOLERANCE AFTER FETAL STEM-CELL TRANSPLANTATION 72
INTERLEUKIN-10 72
Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study 71
Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial 71
Stability of human rapamycin-expanded CD4(+)CD25(+) T regulatory cells 70
Induction of isotype switching and Ig production by CD5+ and CD10+ human fetal B cells 69
Clinical improvement and normalized Th1 cytokine profile in early and long-term Interferon-alpha treatment in a suspected case of Hyper-IgE Syndrome 69
Treatment with rapamycin can restore regulatory T-cell function in IPEX patients 69
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning 67
Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway 65
Antigen-specific cytotoxic T cells mediate human fetal pancreas allograft rejection in SCID-hu mice 65
Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency 65
In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases 65
Efficacy of gene therapy for Wiskott-Aldrich syndrome using a WAS promoter/cDNA-containing lentiviral vector and nonlethal irradiation 64
Human T-and B-cell functions in SCID-hu mice 64
The capacity of interleukin-4 to induce in vitro IgE synthesis by B cells of patients with common variable immunodeficiency 64
Revertant T lymphocytes in a patient with Wiskott-Aldrich syndrome: Analysis of function and distribution in lymphoid organs 64
Rapamycin selectively expands CD4(+)CD25(+)FoxP3(+) regulatory T cells 62
HUMAN HEMATOPOIETIC-CELLS AND THYMIC EPITHELIAL-CELLS INDUCE TOLERANCE VIA DIFFERENT MECHANISMS IN THE SCID-HU MOUSE THYMUS 62
IgE content of commercial intravenous IgG preparations 62
Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice 62
Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans 61
Rapamycin prevents and breaks the anti-CD3-induced tolerance in NOD mice 60
Recombinant human interleukin 10 suppresses gliadin dependent T cell activation in ex vivo cultured coeliac intestinal mucosa 60
STAT5-signaling cytokines regulate the expression of FOXP3 in CD4(+)CD25(+) regulatory T cells and CD4(+)CD25(-) effector T cells 60
Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25(+)CD4(+) Tr cells 60
Isolation and expression of human cytokine synthesis inhibitory factor (CSIF/IL-10) cDNA clones: Homology to Epstein-Barr virus open reading frame BCRF1 60
IL-10-Engineered Human CD4+ Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism 60
Antigen-specific dependence of Tr1-cell therapy in preclinical models of islet transplantation 59
Integration profile of retroviral vector in gene therapy treated patients is cell-specific according to gene expression and chromatin conformation of target cell 59
Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation 59
Molecular and functional characterization of allogantigen-specific anergic T cells suitable for cell therapy 59
CD4+ T cells from IPEX patients convert into functional and stable regulatory T cells by FOXP3 gene transfer 59
Frequency and targeted detection of HLA-DPB1 T cell epitope disparities relevant in unrelated hematopoietic stem cell transplantation 59
The FLK2/FLT3 ligand synergizes with interleukin-7 in promoting stromal-cell-independent expansion and differentiation of human fetal pro-B cells in vitro 58
PROGRESS IN THE EX-VIVO EXPANSION OF HEMATOPOIETIC PROGENITORS 58
The cellular and molecular mechanisms of immuno-suppression by human type 1 regulatory T cells 58
Autoreactive T cell clones specific for class I and class II HLA antigens isolated from a human chimera 58
The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatoy cells 58
Genomic organization of the human T-cell antigen-receptor α/δ locus 58
In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells 58
Comment on M. Guillot-Delost et al. (2008;10:834-846): Clinical-grade preparation of human natural regulatory T cells encoding the thymidine kinase suicide gene as a safety gene 57
In vivo and in vitro anti-tetanus toxoid antibody production in patients with HLA-mismatched T cells following fetal liver and thymus transplantations 57
Thymic factor therapy of viral infections in childhood 57
Preclinical safety and efficacy of human CD34(+) cells transduced with lentiviral vector for the treatment of Wiskott-Aldrich syndrome. 57
Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by IL-4 and a signal provided by activated CD4+ T cell clones 57
REGULATION OF HUMAN IGE SYNTHESIS - THE ROLE OF CD4+ AND CD8+ T-CELLS AND THE INHIBITORY EFFECTS OF INTEREFON-ALPHA 57
Gene correction for SCID-X1 in long-term hematopoietic stem cells 57
Regulatory T cells: prospective for clinical application in hematopoietic stem cell transplantation 56
IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells 56
Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity 56
Enforced IL-10 Expression Confers Type 1 Regulatory T Cell (Tr1) Phenotype and Function to Human CD4(+) T Cells 56
Genotypes and haplotypes in the 3' untranslated region of the HLA-G gene and their association with clinical outcome of hematopoietic stem cell transplantation for beta-thalassemia 56
Gene therapy for adenosine deaminase deficiency 55
T- regulatory 1 cells: a novel subset of CD4+ T cells with immunoregolatory properties 55
Immune reconstitution in ADA-SCID after PBL gene therapy and discontinuation of enzyme replacement 55
IL-4 INDUCES HUMAN B-CELL MATURATION AND IGE SYNTHESIS IN SCID-HU MICE - INHIBITION OF ONGOING IGE PRODUCTION BY IN-VIVO TREATMENT WITH AN IL-4/IL-13 RECEPTOR ANTAGONIST 55
Type 1 T regulatory cells and their relationship with CD4+CD25+ T regulatory cells 55
Totale 7.899
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Categoria #
all - tutte 116.829
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 116.829
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2020/20213 0 0 0 0 0 0 0 0 0 3 0 0
2021/2022174 0 0 0 83 11 6 1 7 6 52 1 7
2022/20231.599 660 370 95 5 9 148 49 75 146 13 15 14
2023/2024817 37 38 82 73 50 152 70 85 4 42 61 123
2024/20253.855 527 63 51 128 99 331 426 298 754 631 245 302
2025/202610.418 786 869 927 1.675 605 297 1.137 800 2.884 438 0 0
Totale 16.930