IRIS
RONCAROLO, MARIA GRAZIA
 Distribuzione geografica
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Continente #
AS - Asia 6.386
EU - Europa 5.487
NA - Nord America 3.954
SA - Sud America 1.629
AF - Africa 109
OC - Oceania 23
Continente sconosciuto - Info sul continente non disponibili 2
Totale 17.590
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Nazione #
US - Stati Uniti d'America 3.785
RU - Federazione Russa 3.107
SG - Singapore 2.177
CN - Cina 2.128
BR - Brasile 1.344
SE - Svezia 888
HK - Hong Kong 824
VN - Vietnam 548
IT - Italia 479
FR - Francia 308
DE - Germania 180
BD - Bangladesh 168
IN - India 137
GB - Regno Unito 119
AR - Argentina 114
FI - Finlandia 89
CA - Canada 82
AT - Austria 59
ID - Indonesia 57
MX - Messico 53
EC - Ecuador 51
IQ - Iraq 50
JP - Giappone 48
NL - Olanda 46
IE - Irlanda 42
ES - Italia 38
PL - Polonia 34
TR - Turchia 34
ZA - Sudafrica 28
CO - Colombia 27
CL - Cile 26
PK - Pakistan 26
MY - Malesia 25
KR - Corea 24
PY - Paraguay 24
AU - Australia 22
UA - Ucraina 21
VE - Venezuela 18
AE - Emirati Arabi Uniti 16
MA - Marocco 16
PH - Filippine 16
SA - Arabia Saudita 16
TN - Tunisia 16
UZ - Uzbekistan 13
UY - Uruguay 11
JM - Giamaica 10
KE - Kenya 10
DZ - Algeria 9
CH - Svizzera 8
EG - Egitto 8
ET - Etiopia 8
RO - Romania 8
JO - Giordania 7
LT - Lituania 7
NP - Nepal 7
PE - Perù 7
BA - Bosnia-Erzegovina 6
GR - Grecia 6
IL - Israele 6
KW - Kuwait 6
KZ - Kazakistan 6
LB - Libano 6
PT - Portogallo 6
AL - Albania 5
AZ - Azerbaigian 5
BE - Belgio 5
BO - Bolivia 5
DO - Repubblica Dominicana 5
LV - Lettonia 5
BG - Bulgaria 4
BH - Bahrain 4
CR - Costa Rica 4
GE - Georgia 4
IR - Iran 4
PS - Palestinian Territory 4
SK - Slovacchia (Repubblica Slovacca) 4
SY - Repubblica araba siriana 4
HU - Ungheria 3
TH - Thailandia 3
AM - Armenia 2
BB - Barbados 2
BY - Bielorussia 2
CG - Congo 2
GT - Guatemala 2
LA - Repubblica Popolare Democratica del Laos 2
MD - Moldavia 2
NG - Nigeria 2
NI - Nicaragua 2
OM - Oman 2
PA - Panama 2
RS - Serbia 2
SN - Senegal 2
TT - Trinidad e Tobago 2
TW - Taiwan 2
AO - Angola 1
BN - Brunei Darussalam 1
BQ - ???statistics.table.value.countryCode.BQ??? 1
CI - Costa d'Avorio 1
CM - Camerun 1
CY - Cipro 1
Totale 17.569
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Città #
Singapore 823
Hong Kong 804
Moscow 686
San Jose 605
Ashburn 535
Dallas 498
Shanghai 393
Hefei 304
Lawrence 292
Princeton 292
Lauterbourg 266
Ho Chi Minh City 204
Beijing 164
New York 147
Hanoi 120
São Paulo 113
Milan 96
Los Angeles 81
Helsinki 77
Santa Clara 73
Nuremberg 60
The Dalles 46
Rio de Janeiro 43
Boardman 39
Dublin 38
Pune 36
Rome 35
Belo Horizonte 34
Brooklyn 34
Orem 33
Tokyo 32
Vienna 31
Warsaw 31
Brasília 30
Guangzhou 30
Washington 30
Montreal 29
Da Nang 28
Columbus 25
London 24
Shenzhen 24
Seattle 23
Chicago 22
Curitiba 22
Toronto 22
Haiphong 21
Phoenix 21
Denver 20
Johannesburg 20
Munich 20
Porto Alegre 20
Salvador 20
Baghdad 19
Chennai 19
Houston 17
Jakarta 17
Biên Hòa 16
Dhaka 16
Guayaquil 16
Naples 16
Santiago 16
Ankara 15
Campinas 15
Hangzhou 15
Poplar 15
Quito 15
Stockholm 15
Atlanta 14
Buffalo 14
Mexico City 14
Mumbai 14
Guarulhos 13
Paris 13
San Rafael 13
Tianjin 13
Boston 12
Kuala Lumpur 12
Ribeirão Preto 12
San Francisco 12
Tashkent 12
Changsha 11
Santo André 11
Sorocaba 11
Sydney 11
Caxias do Sul 10
Charlotte 10
Council Bluffs 10
Frankfurt am Main 10
Ha Long 10
Kingston 10
Lahore 10
Montevideo 10
Philadelphia 10
Turku 10
Goiânia 9
Las Vegas 9
Madrid 9
Monza 9
New Delhi 9
Riyadh 9
Totale 8.124
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Nome #
Lentiviral hematopoietic stem cell gene therapy benefits metachromatic leukodystrophy 389
Loss of mismatched HLA in leukemia after stem-cell transplantation 200
INTERLEUKIN-10 (IL-10) AND VIRAL-IL-10 STRONGLY REDUCE ANTIGEN-SPECIFIC HUMAN T-CELL PROLIFERATION BY DIMINISHING THE ANTIGEN-PRESENTING CAPACITY OF MONOCYTES VIA DOWN-REGULATION OF CLASS-II MAJOR HISTOCOMPATIBILITY COMPLEX EXPRESSION 184
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors 139
Alterations in the adenosine metabolism and CD39/CD73 adenosinergic machinery cause loss of Treg cell function and autoimmunity in ADA-deficient SCID 132
Altered intracellular and extracellular signaling leads to impaired T-cell functions in ADA-SCID patients 122
Pruritus characteristics in a large Italian cohort of psoriatic patients 117
A hypomorphic R229Q Rag2 mouse mutant recapitulates human Omenn syndrome 115
Bone marrow as source of hematopoietic stem cells for human gene therapy of beta thalassemia 115
ADA-deficient SCID is associated with a specific microenvironment and bone phenotype characterized by RANKL/OPG imbalance and osteoblast insufficiency 115
Abnormalities of acid-base balance and predisposition to metabolic acidosis in Metachromatic Leukodystrophy patients 111
A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis 110
Absence of VOD in paediatric thalassaemic HSCT recipients using defibrotide prophylaxis and intravenous Busulphan 108
Induction of isotype switching and Ig production by CD5+ and CD10+ human fetal B cells 107
Gene therapy for immunodeficiency due to adenosine deaminase deficiency 107
A SCID PATIENT RECONSTITUTED WITH HLA-INCOMPATIBLE FETAL STEM-CELLS AS A MODEL FOR STUDYING TRANSPLANTATION TOLERANCE 107
Erratum: IL-10-Engineered Human CD4+ Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism (Molecular Therapy (2017) 25(10) (2254–2269), (S1525001617303143), (10.1016/j.ymthe.2017.06.029)) 107
Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study 104
A transgenic model to analyze the immunoregulatory role of IL-10 secreted by antigen-presenting cells 103
WASP regulates suppressor activity of human and murine CD4(+)CD25(+)FOXP3(+) natural regulatory T cells 101
An anti-CD45RO/RB monoclonal antibody modulates T cell responses via induction of apoptosis and generation of regulatory T cells 101
Hepatocyte-targeted expression by integrase-defective lentiviral vectors induces antigen-specific tolerance in mice with low genotoxic risk. 101
A novel human packaging cell line with hematopoietic supportive capacity increases gene transfer into early hematopoietic progenitors 98
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects 98
Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production 98
A proportion of patients with lymphoma may harbor mutations of the perforin gene 97
High incidence of severe cyclosporine neurotoxicity in children affected by haemoglobinopaties undergoing myeloablative haematopoietic stem cell transplantation: early diagnosis and prompt intervention ameliorates neurological outcome 97
In vivo delivery of a microRNA-regulated transgene induces antigen-specific regulatory T cells and promotes immunologic tolerance 93
Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T cells 89
ANTI-SCID MOUSE REACTIVITY SHAPES THE HUMAN CD4(+) T-CELL REPERTOIRE IN HU-P8L-SCID CHIMERAS 89
Interleukin-10-secreting type 1 regulatory T cells in rodents and humans 88
Insulin B chain 9-23 gene transfer to hepatocytes protects from type 1 diabetes by inducing Ag-specific FoxP3+ Tregs 88
Health related quality of life in Middle Eastern children with beta-thalassemia 87
Correction of ß-thalassemia major by gene transfer in hematopoietic progenitors of pediatric patients 87
A novel function of FOXP3 in humans: intrinsic regulation of conventional T cells 86
Beneficial autoimmunity in Type 1 diabetes mellitus 85
Administration of Flk2/Flt3 ligand induces expansion of human high-proliferative potential colony-forming cells in the SCID-hu mouse 84
Multilineage hematopoietic reconstitution without clonal selection in ADA-SCID patients treated with stem cell gene therapy 83
Advanced cell-based therapies for the treatment of primary immunodeficiency (Cell-PID) 81
Analysis of galactocerebrosidase activity in the mouse brain by a new histological staining method 81
The quality of life of children and adolescents with X-linked agammaglobulinemia 80
Altered T-cell receptor +CD28- mediated signaling and blocked cell cycle progression in interleukin 10 and transforming growth factor-beta-treated alloreactive T cells that do not induce graft-versus-host disease 77
Liver gene therapy by lentiviral vectors reverses anti-factor IX pre-existing immunity in haemophilic mice 76
UNIQUE CYTOKINE PRODUCTION PROFILE OF ANERGIC HUMAN T-CELLS IN SCID-HU MICE AFTER STAPHYLOCOCCAL-ENTEROTOXIN-B ADMINISTRATION 75
Lentiviral hematopoietic stem cell gene therapy in patients with Wiskott-Aldrich syndrome 75
Stability of human rapamycin-expanded CD4(+)CD25(+) T regulatory cells 74
T-CELL REPERTOIRE AND TOLERANCE AFTER FETAL STEM-CELL TRANSPLANTATION 73
INTERLEUKIN-10 73
Lentiviral haemopoietic stem-cell gene therapy in early-onset metachromatic leukodystrophy: an ad-hoc analysis of a non-randomised, open-label, phase 1/2 trial 72
Correction of ADA-SCID by stem cell gene therapy combined with nonmyeloablative conditioning 71
Treatment with rapamycin can restore regulatory T-cell function in IPEX patients 71
Clinical improvement and normalized Th1 cytokine profile in early and long-term Interferon-alpha treatment in a suspected case of Hyper-IgE Syndrome 69
Efficacy of gene therapy for Wiskott-Aldrich syndrome using a WAS promoter/cDNA-containing lentiviral vector and nonlethal irradiation 67
Differentiation of type 1 T regulatory cells (Tr1) by tolerogenic DC-10 requires the IL-10-dependent ILT4/HLA-G pathway 67
Rapamycin combined with anti-CD45RB mAb and IL-10 or with G-CSF induces tolerance in a stringent mouse model of islet transplantation 67
Enforced IL-10 Expression Confers Type 1 Regulatory T Cell (Tr1) Phenotype and Function to Human CD4(+) T Cells 67
The capacity of interleukin-4 to induce in vitro IgE synthesis by B cells of patients with common variable immunodeficiency 67
Immunological outcome in haploicentical-HSC transplanted patients treated with IL-10-anergizec donor T Cells 67
Antigen-specific cytotoxic T cells mediate human fetal pancreas allograft rejection in SCID-hu mice 66
Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25(+)CD4(+) Tr cells 66
Update on the safety and efficacy of retroviral gene therapy for immunodeficiency due to adenosine deaminase deficiency 66
In Vivo Tracking of Human Hematopoiesis Reveals Patterns of Clonal Dynamics during Early and Steady-State Reconstitution Phases 66
Rapamycin prevents and breaks the anti-CD3-induced tolerance in NOD mice 65
Recombinant human interleukin 10 suppresses gliadin dependent T cell activation in ex vivo cultured coeliac intestinal mucosa 65
IgE content of commercial intravenous IgG preparations 65
Human T-and B-cell functions in SCID-hu mice 65
Revertant T lymphocytes in a patient with Wiskott-Aldrich syndrome: Analysis of function and distribution in lymphoid organs 65
STAT5-signaling cytokines regulate the expression of FOXP3 in CD4(+)CD25(+) regulatory T cells and CD4(+)CD25(-) effector T cells 64
Targeting lentiviral vector expression to hepatocytes limits transgene-specific immune response and establishes long-term expression of human antihemophilic factor IX in mice 64
Isolation and expression of human cytokine synthesis inhibitory factor (CSIF/IL-10) cDNA clones: Homology to Epstein-Barr virus open reading frame BCRF1 64
Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans 64
Rapamycin selectively expands CD4(+)CD25(+)FoxP3(+) regulatory T cells 63
HUMAN HEMATOPOIETIC-CELLS AND THYMIC EPITHELIAL-CELLS INDUCE TOLERANCE VIA DIFFERENT MECHANISMS IN THE SCID-HU MOUSE THYMUS 62
IFN-alpha and IL-10 induce the differentiation of human type 1 T regulatory cells 62
Molecular and functional characterization of allogantigen-specific anergic T cells suitable for cell therapy 62
REGULATION OF HUMAN IGE SYNTHESIS - THE ROLE OF CD4+ AND CD8+ T-CELLS AND THE INHIBITORY EFFECTS OF INTEREFON-ALPHA 62
Genomic organization of the human T-cell antigen-receptor α/δ locus 61
CD4+ T cells from IPEX patients convert into functional and stable regulatory T cells by FOXP3 gene transfer 61
Frequency and targeted detection of HLA-DPB1 T cell epitope disparities relevant in unrelated hematopoietic stem cell transplantation 61
Gene correction for SCID-X1 in long-term hematopoietic stem cells 61
PROGRESS IN THE EX-VIVO EXPANSION OF HEMATOPOIETIC PROGENITORS 60
Autoreactive T cell clones specific for class I and class II HLA antigens isolated from a human chimera 60
Human IL2RA null mutation mediates immunodeficiency with lymphoproliferation and autoimmunity 60
Integration profile of retroviral vector in gene therapy treated patients is cell-specific according to gene expression and chromatin conformation of target cell 60
HLA-HAPLOIDENTICAL UMBILICAL-CORD BLOOD STEM-CELL TRANSPLANTATION IN A CHILD WITH ADVANCED LEUKEMIA - CLINICAL OUTCOME AND ANALYSIS OF HEMATOPOIETIC RECOVERY 60
The presence of normal EBV-specific, HLA-restricted cytotoxic activity in two XLP patients with hypogammaglobulinemia. 60
IL-10-Engineered Human CD4+ Tr1 Cells Eliminate Myeloid Leukemia in an HLA Class I-Dependent Mechanism 60
Antigen-specific dependence of Tr1-cell therapy in preclinical models of islet transplantation 59
The FLK2/FLT3 ligand synergizes with interleukin-7 in promoting stromal-cell-independent expansion and differentiation of human fetal pro-B cells in vitro 59
The cellular and molecular mechanisms of immuno-suppression by human type 1 regulatory T cells 59
The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatoy cells 59
In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells 59
Regulatory T cells: prospective for clinical application in hematopoietic stem cell transplantation 58
Comment on M. Guillot-Delost et al. (2008;10:834-846): Clinical-grade preparation of human natural regulatory T cells encoding the thymidine kinase suicide gene as a safety gene 58
Evidence for long-term efficacy and safety of gene therapy for Wiskott Aldrich syndrome in preclinical models 58
Temporal, quantitative, and functional characteristics of single-KIR-positive alloreactive natural killer cell recovery account for impaired graft-versus-leukemia activity after haploidentical hematopoietic stem cell transplantation 58
Human B cell clones can be induced to proliferate and to switch to IgE and IgG4 synthesis by IL-4 and a signal provided by activated CD4+ T cell clones 58
LYMPHOID AND MYELOID DIFFERENTIATION OF FETAL LIVER CD34+ LINEAGE(-) CELLS IN HUMAN THYMIC ORGAN-CULTURE 58
Gene therapy for adenosine deaminase deficiency 57
In vivo and in vitro anti-tetanus toxoid antibody production in patients with HLA-mismatched T cells following fetal liver and thymus transplantations 57
Totale 8.369
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Categoria #
all - tutte 125.144
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 125.144
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022174 0 0 0 83 11 6 1 7 6 52 1 7
2022/20231.599 660 370 95 5 9 148 49 75 146 13 15 14
2023/2024817 37 38 82 73 50 152 70 85 4 42 61 123
2024/20253.855 527 63 51 128 99 331 426 298 754 631 245 302
2025/202611.213 786 869 927 1.675 605 297 1.137 800 2.884 618 301 314
Totale 17.725