IRIS
BONINI, MARIA CHIARA
 Distribuzione geografica
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Continente #
EU - Europa 2.054
NA - Nord America 1.608
AS - Asia 775
OC - Oceania 12
SA - Sud America 12
AF - Africa 5
Totale 4.466
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Nazione #
US - Stati Uniti d'America 1.589
SE - Svezia 1.099
SG - Singapore 383
RU - Federazione Russa 365
IT - Italia 344
CN - Cina 184
FI - Finlandia 75
HK - Hong Kong 73
DE - Germania 55
IE - Irlanda 52
JP - Giappone 51
IN - India 36
GB - Regno Unito 21
SA - Arabia Saudita 15
FR - Francia 12
CA - Canada 11
IL - Israele 11
IR - Iran 10
CH - Svizzera 8
AT - Austria 6
AU - Australia 6
BR - Brasile 6
NZ - Nuova Zelanda 6
DO - Repubblica Dominicana 5
ES - Italia 5
AR - Argentina 4
NL - Olanda 4
TH - Thailandia 4
TW - Taiwan 4
DK - Danimarca 3
MX - Messico 3
BE - Belgio 2
DZ - Algeria 2
EG - Egitto 2
KR - Corea 2
PE - Perù 2
IQ - Iraq 1
LU - Lussemburgo 1
MG - Madagascar 1
MK - Macedonia 1
PK - Pakistan 1
UA - Ucraina 1
Totale 4.466
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Città #
Lawrence 409
Princeton 409
Singapore 232
Ashburn 188
Milan 145
New York 137
Moscow 136
Shanghai 127
Helsinki 70
Dublin 49
Boardman 46
Washington 28
Rome 23
Pune 19
Los Angeles 14
Seattle 13
Tokyo 11
Borås 10
Hanover 8
Turin 8
Brescia 7
Rockville 7
Beijing 6
Boston 6
San Jose 6
Shijiazhuang 6
Andover 5
Cotui 5
Falls Church 5
Jeddah 5
Lappeenranta 5
Overland Park 5
Acton 4
Al Qatif 4
Bangkok 4
Bologna 4
Cambridge 4
Hong Kong 4
Hyderabad 4
Moreno Valley 4
Mountain View 4
Naples 4
Redwood City 4
Santa Clara 4
St Petersburg 4
Toronto 4
Vauderens 4
Zurich 4
Aci Sant'Antonio 3
Ballincollig 3
Busto Arsizio 3
Cantù 3
Chapel Hill 3
Chiyoda-ku 3
Cinisello Balsamo 3
Clifton 3
Ferrara 3
Florence 3
Genoa 3
Hadera 3
Ibaraki 3
Iowa City 3
Kfar Saba 3
London 3
Melbourne 3
Monrovia 3
Oberndorf bei Salzburg 3
Osimo 3
Paris 3
Pavia 3
Philadelphia 3
Phoenix 3
Pomona 3
Riyadh 3
Segrate 3
St Louis 3
Zhengzhou 3
Albairate 2
Albuquerque 2
Avellino 2
Barcelona 2
Baronissi 2
Birmingham 2
Bordeaux 2
Borgomanero 2
Brembate di Sopra 2
Buenos Aires 2
Burnaby 2
Burolo 2
Cagliari 2
Castelli Calepio 2
Castelseprio 2
Castenaso 2
Central 2
Chaoyang 2
Chelyabinsk 2
Cittadella 2
Copenhagen 2
Dalmine 2
Ekimaedori 2
Totale 2.347
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Nome #
CD4 CAR-T cells targeting CD19 play a key role in exacerbating cytokine release syndrome, while maintaining long-term responses 103
MODELING ADOPTIVE IMMUNOTHERAPY IN MOUSE-HUMANS CHIMERAS TO IDENTIFY NOVEL MECHANISMS OF LEUKEMIA IMMUNOEDITING 71
Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study 63
Clinical impact of suicide gene therapy in allogeneic hematopoietic stem cell transplantation 55
Case report: Ponatinib as a bridge to CAR-T cells and subsequent maintenance in a patient with relapsed/refractory Philadelphia-like acute lymphoblastic leukemia 39
Revealing and harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells 36
Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation 36
A clinical protocol for gene transfer into peripheral blood lymphocytes for in vivo immunomodulation of donor anti-tumor immunity in patients affected by recurrent disease after allogeneic bone marrow transplantation 34
Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation 32
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors 31
CRISPR-based gene disruption and integration of high-avidity, WT1-specific T cell receptors improve antitumor T cell function 30
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer 29
Unconventional CD147-dependent platelet activation elicited by SARS-CoV-2 in COVID-19 28
Immunoediting of the genomic and transcriptional profile of acute myeloid leukaemia in response to allogeneic haematopoietic stem cell transplantation 27
Biobanking for COVID-19 research 27
A longitudinal analysis of humoral, T cellular response and influencing factors in a cohort of healthcare workers: Implications for personalized SARS-CoV-2 vaccination strategies 25
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory 25
Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies 25
Immune Reconstitution-Based Score for Risk Stratification of Chronic Graft-Versus-Host Disease Patients 25
FAS-based suicide gene strategy for controlled GvHD: An alternative to HSV-tk. 23
Site-specific integration and tailoring of cassette design for sustainable gene transfer 23
Abrogation of GvHD and early immune reconstitution after infusion of HSV-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation. 22
Loss of mismatched HLA in leukemia after stem-cell transplantation 22
Posttransplantation Cyclophosphamide- and Sirolimus-Based Graft-Versus-Host-Disease Prophylaxis in Allogeneic Stem Cell Transplant 22
Interleukin-7 improves the fitness of regulatory T cells for adoptive transfer 22
Dynamics of polyclonal immuno-reconstitution after allogeneic transplant with post-transplant cyclophosphamide and letermovir 21
T cells for suicide gene therapy: Activation, functionality and clinical relevance 21
A new suicide system based on gene transfer of FAS into donor lymphocytes for controlled GVL. 21
A humanized Fas receptor-based suicide switch expressed in human T lymphocytes for the induction of controlled graft versus leukemia. 21
Allogeneic hematopoietic stem cell transplantation for neuromyelitis optica. 21
A CD8α− Subset of CD4+SLAMF7+ Cytotoxic T Cells Is Expanded in Patients With IgG4-Related Disease and Decreases Following Glucocorticoid Treatment 21
CD4+ Memory Stem T Cells Recognizing Citrullinated Epitopes Are Expanded in Patients With Rheumatoid Arthritis and Sensitive to Tumor Necrosis Factor Blockade 21
A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease 20
In-vivo T-regs generation by rapamycin-mycophenolate-ATG as a new platform for GvHD prophylaxis in T-cell repleted unmanipulated haploidentical peripheral stem cell transplantation: results in 59 patients 20
T Cell Suicide Gene Therapy Prompts Thymic Renewal in Adults After Haploidentical Hematopoietic Stem Cell Transplantation in the Absence of Post-Transplant Immunesuppression 20
Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation 20
CRISPR/CAS9-BASED GENOME EDITING TO MODEL THE ANTI-LEUKEMIA IMMUNE RESPONSE AND IDENTIFY ITS MOLECULAR PLAYERS 19
Adoptive immunotherapy with genetically modified lymphocytes in allogeneic stem cell transplantation 19
Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy 19
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 19
TCR gene editing results in effective immunotherapy of leukaemia without the development of GvHD 19
CXCL10 levels at hospital admission predict COVID-19 outcome: hierarchical assessment of 53 putative inflammatory biomarkers in an observational study 19
A novel immunopeptidomic-based pipeline for the generation of personalized oncolytic cancer vaccines 19
Infusion of HSV-tk genetically-engineered donor lymphocytes restores anti-viral immunity early after allogeneic BMT. 18
A T cell epitope encoded by a subset HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation 18
819. Molecular Follow-Up of Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation and Donor Lymphocytes Transduced with a Retroviral Vector Expressing HSV-TK and ∆LNGFR 18
From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia 18
Anti-SARS-CoV-2 T-stem cell memory persists in ocrelizumab-treated MS patients 17
Case Report: Favorable outcome of allogeneic hematopoietic stem cell transplantation in SARSCoV2 positive recipient, risk-benefit balance between infection and leukemia 17
Expression of inducible factors reprograms CAR-T cells for enhanced function and safety 17
Suicide gene transduced for the regulation of the graft-versus-leukemia effect 17
Adoptive T-cell therapy for cancer: The era of engineered T cells 17
A novel self-lipid antigen targets human T cells against CD1c(+) leukemias 17
T Cell Receptor Gene Transfer into Early Differentiated Lymphocytes by Lentiviral Vectors for Safe and Effective Adoptive Immune Therapy of Leukemia 17
A dual role for genetically modified lymphocytes in cancer immunotherapy 17
Early molecular diagnosis of aspergillosis in a patient with acute myeloid leukaemia 17
Allogeneic haematopoietic stem cell transplantation in refractory neuromyelitis optica spectrum disorders 17
Immune monitoring in allogeneic hematopoietic stem cell transplant recipients: a survey from the EBMT-CTIWP 17
NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease 17
HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia 17
Clinical and molecular features associated with acute myeloid leukemia engraftment in immunodeficient mouse models 17
Flow cytometry data mining by cytoChain identifies determinants of exhaustion and stemness in TCR-engineered T cells 17
Time to evolve: predicting engineered T cell-associated toxicity with next-generation models 16
Immune Effector Cell-Associated Hematotoxicity (ICAHT): EHA/EBMT Consensus Grading and Best Practice Recommendations 16
Targeted genome editing in human repopulating haematopoietic stem cells 16
Herpes simplex virus thymidine kinase gene transfer for controlled graft-versus-host disease and graft-versus-leukemia: Clinical follow-up and improved new vectors 16
Improving the safety of cell therapy with the TK-suicide gene. 16
Use of HSV-TK transduced donor lymphocytes in the context of allogeneic bone marrow transplantation: A paradigm of current applications and limitations in gene therapy 16
A pilot study of HSV-TK gene transfer into donor peripheral blood lymphocytes for controlled GVL after allo-BMT. 16
Rapamycin-Based GvHD Prophylaxis Is Effective in T-Cell Replete Unmanipulated Haploidentical Peripheral Stem Cell Transplantation for Advanced Haematological Malignancies: Results in 46 Patients 16
Genomic typing for patient-specific human leukocyte antigen-alleles is an efficient tool for relapse detection of high-risk hematopoietic malignancies after stem cell transplantation from alternative donors 16
A phase II multicenter trial of HSV-TK engineered donor lymphocytes after haplo-identical HSCT: Early immune reconstitution and abrogation of GvHD 16
Cytomegalovirus-specific T cells restricted for shared and donor human leukocyte antigens differentially impact on Cytomegalovirus reactivation risk after allogeneichematopoietic stem cell transplantation 15
Suicide gene transduced T-cells for the regulation of the graft-versus-leukemia effect 15
Targeting Integration to Selected Genomic Loci and In Situ Tailoring of Cassette Design Allows Robust Transgene Expression without Perturbing Endogenous Transcription 15
Erratum: Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory (Science Translational Medicine (2015) 7:319 (319er9)) 15
Human Herpesvirus 6 Infection Following Haploidentical Transplantation: Immune Recovery and Outcome 15
In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells 15
T memory stem cells in health and disease 15
Enhancing anti-tumour efficacy with immunotherapy combinations 15
Graft-versus leukemia effect of HLA-haploidentical central-memory T cells expanded with leukemic APCs and modified with a suicide gene 15
Human T cells engineered with a leukemia lipid-specific TCR enables donor-unrestricted recognition of CD1c-expressing leukemia 15
Safety and Efficacy of Donor T Cells Engineered with Herpes Simplex Virus Thymidine-Kinase Suicide Gene (TK Cells) Given after T-Cell Depleted (TCD) Haploidentical Hematopoietic Transplantation (Haplo-HSCT): Results of a 14-Year Follow-Up in 45 Patients 14
Long term follow-up in 30 patients receiving HSV-TK transduced donor lymphocytes after allo-BMT. 14
Reinfusion of Hsv-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation provide early immune reconstitution without GvHD. 14
Alterations in the genomic and transcriptional profile of leukemia upon the immune pressure of allogenic hematopoietic stem cell transplantation: tracking immunoediting by high-throughput techniques 14
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 14
Early and Effective Immune-Recovery by Gene-Engineered Lymphocytes after Haploidentical Transplantation for Leukemia Abate Late Transplant Mortality 14
NK cell recovery after haploidentical HSCT with posttransplant cyclophosphamide: Dynamics and clinical implications 14
TCR Redirected T Cells for Cancer Treatment: Achievements, Hurdles, and Goals 14
Acute Myeloid Leukemia Relapses after Allogenenic HSCT Display a Distinctive Immune-Related Signature, with Frequent and Functionally Relevant Alterations in HLA Class II Antigen Presentation and T Cell Costimulation 14
Allogeneic Hematopoietic Stem Cell Transplantation For Severe Neuromyelitis Optica 14
The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies 14
Epigenetic checkpoints regulate the fate and function of CAR-T cells 13
CD4 CAR T Cells Drive Extensive CD8 CAR T Cell Expansion, Leading to Severe Cytokine Release Syndrome 13
Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells 13
Transcriptional Enhancers Induce Insertional Gene Deregulation Independently From the Vector Type and Design 13
Rapid and effective immune reconstitution with HSV-TK engineered donor lymphocyte add-backs after Haplo-HSCT 13
Generation of human memory stem T cells after haploidentical T-replete hematopoietic stem cell transplantation 13
A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR 13
Totale 2.117
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Categoria #
all - tutte 81.058
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 81.058
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202031 18 0 0 5 0 0 1 1 0 6 0 0
2020/202187 0 0 0 3 2 7 70 0 5 0 0 0
2021/2022278 0 0 0 125 25 7 18 34 13 23 7 26
2022/20232.256 918 480 124 22 55 256 84 124 96 28 50 19
2023/20241.308 51 58 140 129 118 240 156 99 21 53 62 181
2024/2025695 695 0 0 0 0 0 0 0 0 0 0 0
Totale 4.732