IRIS
BONINI, MARIA CHIARA
 Distribuzione geografica
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Continente #
AS - Asia 10.092
EU - Europa 9.606
NA - Nord America 7.225
SA - Sud America 2.877
Continente sconosciuto - Info sul continente non disponibili 391
AF - Africa 222
OC - Oceania 25
Totale 30.438
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Nazione #
US - Stati Uniti d'America 6.782
RU - Federazione Russa 5.501
SG - Singapore 3.819
CN - Cina 2.933
BR - Brasile 2.344
HK - Hong Kong 1.280
IT - Italia 1.230
SE - Svezia 1.139
VN - Vietnam 1.025
FR - Francia 479
DE - Germania 368
GB - Regno Unito 219
BD - Bangladesh 213
AR - Argentina 203
CA - Canada 189
IN - India 174
FI - Finlandia 135
EC - Ecuador 119
MX - Messico 113
JP - Giappone 110
NL - Olanda 107
ID - Indonesia 99
AT - Austria 96
ZA - Sudafrica 73
CO - Colombia 65
TR - Turchia 65
IE - Irlanda 63
IQ - Iraq 62
ES - Italia 58
PY - Paraguay 51
PL - Polonia 49
PK - Pakistan 36
MA - Marocco 33
SA - Arabia Saudita 33
UZ - Uzbekistan 33
VE - Venezuela 29
UA - Ucraina 28
CR - Costa Rica 27
TN - Tunisia 27
CL - Cile 26
JM - Giamaica 25
DZ - Algeria 24
MY - Malesia 22
EG - Egitto 20
AU - Australia 19
PH - Filippine 19
UY - Uruguay 19
CH - Svizzera 18
IL - Israele 16
KE - Kenya 16
KR - Corea 16
BE - Belgio 15
LT - Lituania 15
PE - Perù 14
DO - Repubblica Dominicana 13
NP - Nepal 13
TT - Trinidad e Tobago 13
IR - Iran 12
AE - Emirati Arabi Uniti 10
GT - Guatemala 10
JO - Giordania 10
LB - Libano 10
NI - Nicaragua 10
TH - Thailandia 10
HN - Honduras 9
MD - Moldavia 9
BB - Barbados 8
PT - Portogallo 8
TW - Taiwan 8
AL - Albania 7
BY - Bielorussia 7
DK - Danimarca 7
SV - El Salvador 7
AM - Armenia 6
CI - Costa d'Avorio 6
GE - Georgia 6
KW - Kuwait 6
NZ - Nuova Zelanda 6
SY - Repubblica araba siriana 6
AZ - Azerbaigian 5
CZ - Repubblica Ceca 5
GR - Grecia 5
HU - Ungheria 5
KG - Kirghizistan 5
KH - Cambogia 5
KZ - Kazakistan 5
OM - Oman 5
PR - Porto Rico 5
RS - Serbia 5
BA - Bosnia-Erzegovina 4
BO - Bolivia 4
CY - Cipro 4
ET - Etiopia 4
MK - Macedonia 4
PA - Panama 4
PS - Palestinian Territory 4
RO - Romania 4
SK - Slovacchia (Repubblica Slovacca) 4
AO - Angola 3
BG - Bulgaria 3
Totale 30.002
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Città #
Singapore 1.532
Moscow 1.209
Hong Kong 1.199
Ashburn 862
Dallas 798
San Jose 784
Shanghai 559
Council Bluffs 504
Hefei 462
Princeton 410
Lawrence 409
Ho Chi Minh City 394
Lauterbourg 392
Milan 364
Beijing 347
New York 308
Hanoi 199
São Paulo 188
Los Angeles 154
Santa Clara 152
Nuremberg 106
Rome 100
Rio de Janeiro 84
Boardman 83
Helsinki 83
Orem 66
Tokyo 66
Dublin 58
Munich 58
Brooklyn 54
Guangzhou 54
London 54
Da Nang 51
Montreal 51
Belo Horizonte 47
Vienna 47
Denver 46
Phoenix 46
Brasília 44
Quito 44
Boston 42
Haiphong 41
Johannesburg 41
Warsaw 41
Chennai 40
Washington 40
Guayaquil 39
Chicago 38
Mexico City 35
Stockholm 35
Atlanta 34
Brescia 34
Turku 34
Frankfurt am Main 33
Manchester 33
Toronto 33
Poplar 32
Houston 31
Tashkent 31
Amsterdam 29
Hangzhou 28
Ankara 27
Curitiba 26
The Dalles 26
Campinas 25
Porto Alegre 25
Shenzhen 25
Baghdad 24
Biên Hòa 24
Turin 24
Columbus 23
Goiânia 23
Omaha 23
Pune 23
Salvador 23
Seattle 23
Tianjin 23
Mumbai 22
Naples 22
Bologna 21
Philadelphia 20
San Francisco 20
Dhaka 19
Hải Dương 19
Querétaro 19
San José 19
Thái Bình 19
Buffalo 18
Fortaleza 18
Manaus 18
Recife 18
Buenos Aires 17
Caxias do Sul 17
Guarulhos 17
Jakarta 17
Lappeenranta 17
Santo André 17
Shijiazhuang 17
Can Tho 16
Montevideo 16
Totale 14.022
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Nome #
Immune Effector Cell-Associated Hematotoxicity (ICAHT): EHA/EBMT Consensus Grading and Best Practice Recommendations 241
CD4 CAR-T cells targeting CD19 play a key role in exacerbating cytokine release syndrome, while maintaining long-term responses 228
Loss of mismatched HLA in leukemia after stem-cell transplantation 217
Rapamycin-Based GvHD Prophylaxis Is Effective in T-Cell Replete Unmanipulated Haploidentical Peripheral Stem Cell Transplantation for Advanced Haematological Malignancies: Results in 46 Patients 216
Use of HSV-TK transduced donor lymphocytes in the context of allogeneic bone marrow transplantation: A paradigm of current applications and limitations in gene therapy 213
Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation 185
Revealing and harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells 184
Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study 178
Blockade of αvβ6 and αvβ8 integrins with a chromogranin A-derived peptide inhibits TGFβ activation in tumors and suppresses tumor growth 176
Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies 175
Systemic delivery of cadherin 17–specific CAR T cells allows effective and safe targeting of colorectal cancer liver metastases 173
Clinical impact of suicide gene therapy in allogeneic hematopoietic stem cell transplantation 172
Dynamics of polyclonal immuno-reconstitution after allogeneic transplant with post-transplant cyclophosphamide and letermovir 168
A longitudinal analysis of humoral, T cellular response and influencing factors in a cohort of healthcare workers: Implications for personalized SARS-CoV-2 vaccination strategies 168
Case report: Ponatinib as a bridge to CAR-T cells and subsequent maintenance in a patient with relapsed/refractory Philadelphia-like acute lymphoblastic leukemia 160
CRISPR-based gene disruption and integration of high-avidity, WT1-specific T cell receptors improve antitumor T cell function 153
Epithelial ovarian cancer is infiltrated by activated effector T cells co-expressing CD39, PD-1, TIM-3, CD137 and interacting with cancer cells and myeloid cells 152
Biobanking for COVID-19 research 149
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors 147
A CD8α− Subset of CD4+SLAMF7+ Cytotoxic T Cells Is Expanded in Patients With IgG4-Related Disease and Decreases Following Glucocorticoid Treatment 147
Case Report: Favorable outcome of allogeneic hematopoietic stem cell transplantation in SARSCoV2 positive recipient, risk-benefit balance between infection and leukemia 146
TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells 140
A clinical protocol for gene transfer into peripheral blood lymphocytes for in vivo immunomodulation of donor anti-tumor immunity in patients affected by recurrent disease after allogeneic bone marrow transplantation 140
Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation 140
Regulatory T cells expressing CD19-targeted chimeric antigen receptor restore homeostasis in Systemic Lupus Erythematosus 139
A T cell epitope encoded by a subset HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation 128
Cytomegalovirus-specific T cells restricted for shared and donor human leukocyte antigens differentially impact on Cytomegalovirus reactivation risk after allogeneichematopoietic stem cell transplantation 127
Fat-to-blood recirculation of partially dysfunctional PD-1+CD4 Tconv cells is associated with dysglycemia in human obesity 126
Unconventional CD147-dependent platelet activation elicited by SARS-CoV-2 in COVID-19 126
Adoptive immunotherapy with genetically modified lymphocytes in allogeneic stem cell transplantation 123
A humanized Fas receptor-based suicide switch expressed in human T lymphocytes for the induction of controlled graft versus leukemia. 123
CD4+ Memory Stem T Cells Recognizing Citrullinated Epitopes Are Expanded in Patients With Rheumatoid Arthritis and Sensitive to Tumor Necrosis Factor Blockade 123
A phase II multicenter trial of HSV-TK engineered donor lymphocytes after haplo-identical HSCT: Early immune reconstitution and abrogation of GvHD 123
NON-GENOMIC ALTERATIONS IN ANTIGEN PRESENTATION AND T CELL COSTIMULATION ARE DISTINCT DRIVERS OF LEUKEMIA IMMUNE ESCAPE AND RELAPSE AFTER HEMATOPOIETIC CELL TRANSPLANTATION 121
Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation 121
Expression of inducible factors reprograms CAR-T cells for enhanced function and safety 120
A novel self-lipid antigen targets human T cells against CD1c(+) leukemias 120
Immune Reconstitution-Based Score for Risk Stratification of Chronic Graft-Versus-Host Disease Patients 119
CAR T cell manufacturing from naive/stem memory T lymphocytes enhances antitumor responses while curtailing cytokine release syndrome 118
MODELING ADOPTIVE IMMUNOTHERAPY IN MOUSE-HUMANS CHIMERAS TO IDENTIFY NOVEL MECHANISMS OF LEUKEMIA IMMUNOEDITING 118
Erratum: Author Correction: Metabolic reprogramming of naïve regulatory T cells by IL-7 and IL-15 promotes their persistence and performance upon adoptive transfer (Communications biology (2025) 8 1 DOI: 10.1038/s42003-024-07381-1.) 117
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer 117
T cells for suicide gene therapy: Activation, functionality and clinical relevance 116
Anti-SARS-CoV-2 T-stem cell memory persists in ocrelizumab-treated MS patients 115
A dual role for genetically modified lymphocytes in cancer immunotherapy 115
A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR 113
819. Molecular Follow-Up of Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation and Donor Lymphocytes Transduced with a Retroviral Vector Expressing HSV-TK and ∆LNGFR 112
Allogeneic hematopoietic stem cell transplantation for neuromyelitis optica. 111
A novel immunopeptidomic-based pipeline for the generation of personalized oncolytic cancer vaccines 111
Antitumor effects of HSV-TK-engineered donor lymphocytes after allogeneic stem-cell transplantation 109
CRISPR/CAS9-BASED GENOME EDITING TO MODEL THE ANTI-LEUKEMIA IMMUNE RESPONSE AND IDENTIFY ITS MOLECULAR PLAYERS 108
Workflow for high-dimensional flow cytometry analysis of T cells from tumor metastases 108
Harnessing CD39 for the Treatment of Colorectal Cancer and Liver Metastases by Engineered T Cells 107
Allogeneic haematopoietic stem cell transplantation in refractory neuromyelitis optica spectrum disorders 107
Human herpesvirus 6-specific T-cell immunity in allogeneic hematopoietic stem cell transplant recipients 106
IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer 106
CXCL10 levels at hospital admission predict COVID-19 outcome: hierarchical assessment of 53 putative inflammatory biomarkers in an observational study 105
Posttransplantation Cyclophosphamide- and Sirolimus-Based Graft-Versus-Host-Disease Prophylaxis in Allogeneic Stem Cell Transplant 105
A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease 104
Graft-versus leukemia effect of HLA-haploidentical central-memory T cells expanded with leukemic APCs and modified with a suicide gene 103
Harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells 103
A new suicide system based on gene transfer of FAS into donor lymphocytes for controlled GVL. 102
Leukemic blasts secondary to myelodysplastic syndromes are molecularly programmed to differentiate into functionally mature dendritic cells 101
The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies 100
Interleukin-7 improves the fitness of regulatory T cells for adoptive transfer 99
TCR Redirected T Cells for Cancer Treatment: Achievements, Hurdles, and Goals 98
HARNESSING CD39 FOR THE TREATMENT OF COLORECTAL CANCER AND LIVER METASTASES BY ENGINEERED T CELLS 97
Acute Myeloid Leukemia Relapses after Allogenenic HSCT Display a Distinctive Immune-Related Signature, with Frequent and Functionally Relevant Alterations in HLA Class II Antigen Presentation and T Cell Costimulation 96
Adoptive T-cell therapy for cancer: The era of engineered T cells 95
Combining Site-Specific Integration and Cassette Design to Achieve Robust Expression Without Impacting Endogenous Gene Expression 95
A model system for functional evaluation of isolated MHC disparities 95
A strategy for introducing and targeting antigen in activated dendritic cells for simultaneous stimulation of CD4 and CD8 cells. 94
Beneficial role of CD8+ T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias: results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting 94
N-Glycosylation Inhibition Hinders Immunosuppressive Activity of Tumor Microenvironment Cells and Improves CAR T Cell Efficacy 94
T-N/SCM Pre-Selection Generates CAR T Cell Products Driving Superior Anti-Tumor Responses While Curtailing Severe CRS 93
Abrogation of GvHD and early immune reconstitution after infusion of HSV-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation. 93
Enhancing anti-tumour efficacy with immunotherapy combinations 93
Flow cytometry data mining by cytoChain identifies determinants of exhaustion and stemness in TCR-engineered T cells 93
Harnessing the tumor microenvironment to boost adoptive T cell therapy with engineered lymphocytes for solid tumors 92
CMV-specific T Cell Counts Early after Allogeneic Hematopoietic Stem Cell Transplantation Stratify the Risk of Subsequent CMV Reactivations: Results of a Prospective Observational Study 92
A pilot study of HSV-TK gene transfer into donor peripheral blood lymphocytes for controlled GVL after allo-BMT. 92
Application of Donor Lymphocytes Expressing a Suicide Gene for Early GvL Induction and Later Control of GvH reactions after Bone Marrow Tranaplantation 92
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells 92
Metabolic reprogramming of naïve regulatory T cells by IL-7 and IL-15 promotes their persistence and performance upon adoptive transfer 90
Human T cells engineered with a leukemia lipid-specific TCR enables donor-unrestricted recognition of CD1c-expressing leukemia 90
CD4 CAR T Cells Drive Extensive CD8 CAR T Cell Expansion, Leading to Severe Cytokine Release Syndrome 89
Combining Targeted Integration and Cassette Design for Robust and Benign Transgene Expression without Impacting Endogenous Gene Transcription 89
An Accelerated CD8+, but Not CD4+, T-Cell Reconstitution Associates with a More Favorable Outcome Following HLA-Haploidentical HSCT: Results from a Retrospective Study of the Cell Therapy and Immunobiology Working Party of the EBMT 89
Alterations in the genomic and transcriptional profile of leukemia upon the immune pressure of allogenic hematopoietic stem cell transplantation: tracking immunoediting by high-throughput techniques 87
Early and Effective Immune-Recovery by Gene-Engineered Lymphocytes after Haploidentical Transplantation for Leukemia Abate Late Transplant Mortality 87
An Accelerated CD8+, but Not CD4+, T -Cell Reconstitution Associates with a More Favorable Outcome Following HLA-Haploidentical HSCT: Results from a Retrospective Study of the Cell Therapy and Immunobiology Working Party of the EBMT 87
Role of HLA-B exon 1 in graft-versus-host disease after unrelated haemopoietic cell transplantation: a retrospective cohort study 86
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory 85
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 84
NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease 84
Autoantibody Production during Chronic Graft-Versus-Host Disease Does Not Associate with Long-Term Persistence of Host B Cells in Humans 83
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 82
AN INNOVATIVE HUMANIZED MOUSE MODEL TO INVESTIGATE THE INTERPLAY BETWEEN IMMUNE SYSTEM AND ACUTE MYELOID LEUKEMIA IN ALLOGENEIC HSCT 82
The longitudinal characterization of immune responses in COVID-19 patients reveals novel prognostic signatures for disease severity, patients’ survival and long COVID 81
Epigenetic checkpoints regulate the fate and function of CAR-T cells 80
Totale 11.988
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Categoria #
all - tutte 202.063
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 202.063
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022278 0 0 0 125 25 7 18 34 13 23 7 26
2022/20232.256 918 480 124 22 55 256 84 124 96 28 50 19
2023/20241.308 51 58 140 129 118 240 156 99 21 53 62 181
2024/20256.305 728 106 99 183 168 479 751 553 1.100 889 600 649
2025/202618.779 1.376 1.517 1.514 2.930 1.380 562 1.488 1.290 4.972 836 481 433
2026/20271.317 484 833 0 0 0 0 0 0 0 0 0 0
Totale 30.438