IRIS
BONINI, MARIA CHIARA
 Distribuzione geografica
Salva come PNG Salva come JPEG
Continente #
AS - Asia 9.965
EU - Europa 9.494
NA - Nord America 6.062
SA - Sud America 2.858
AF - Africa 220
OC - Oceania 25
Continente sconosciuto - Info sul continente non disponibili 4
Totale 28.628
Salva come PNG Salva come JPEG
Nazione #
US - Stati Uniti d'America 5.721
RU - Federazione Russa 5.498
SG - Singapore 3.807
CN - Cina 2.873
BR - Brasile 2.336
HK - Hong Kong 1.274
SE - Svezia 1.139
IT - Italia 1.137
VN - Vietnam 1.019
FR - Francia 479
DE - Germania 364
GB - Regno Unito 215
AR - Argentina 202
BD - Bangladesh 191
IN - India 173
CA - Canada 143
FI - Finlandia 135
EC - Ecuador 114
JP - Giappone 109
MX - Messico 109
NL - Olanda 105
AT - Austria 96
ID - Indonesia 94
ZA - Sudafrica 73
TR - Turchia 65
CO - Colombia 63
IE - Irlanda 63
IQ - Iraq 62
ES - Italia 56
PY - Paraguay 51
PL - Polonia 49
PK - Pakistan 36
MA - Marocco 33
SA - Arabia Saudita 33
UZ - Uzbekistan 33
UA - Ucraina 28
VE - Venezuela 27
TN - Tunisia 26
CL - Cile 25
DZ - Algeria 23
EG - Egitto 20
AU - Australia 19
MY - Malesia 19
PH - Filippine 19
UY - Uruguay 19
CH - Svizzera 18
JM - Giamaica 18
CR - Costa Rica 16
IL - Israele 16
KE - Kenya 16
KR - Corea 16
BE - Belgio 15
LT - Lituania 15
PE - Perù 14
DO - Repubblica Dominicana 13
IR - Iran 12
AE - Emirati Arabi Uniti 10
LB - Libano 10
JO - Giordania 9
MD - Moldavia 9
NP - Nepal 9
TH - Thailandia 8
BB - Barbados 7
BY - Bielorussia 7
DK - Danimarca 7
PT - Portogallo 7
TW - Taiwan 7
AL - Albania 6
AM - Armenia 6
CI - Costa d'Avorio 6
KW - Kuwait 6
NZ - Nuova Zelanda 6
SY - Repubblica araba siriana 6
TT - Trinidad e Tobago 6
AZ - Azerbaigian 5
GE - Georgia 5
GR - Grecia 5
GT - Guatemala 5
HU - Ungheria 5
KG - Kirghizistan 5
KH - Cambogia 5
KZ - Kazakistan 5
NI - Nicaragua 5
OM - Oman 5
RS - Serbia 5
BA - Bosnia-Erzegovina 4
BO - Bolivia 4
CY - Cipro 4
CZ - Repubblica Ceca 4
ET - Etiopia 4
HN - Honduras 4
MK - Macedonia 4
PA - Panama 4
PS - Palestinian Territory 4
RO - Romania 4
SK - Slovacchia (Repubblica Slovacca) 4
SV - El Salvador 4
AO - Angola 3
BG - Bulgaria 3
DM - Dominica 3
Totale 28.588
Salva come PNG Salva come JPEG
Città #
Singapore 1.521
Moscow 1.209
Hong Kong 1.194
Ashburn 820
Dallas 793
San Jose 768
Shanghai 556
Hefei 462
Lawrence 409
Princeton 409
Ho Chi Minh City 392
Lauterbourg 392
Milan 343
Beijing 325
New York 291
Hanoi 198
São Paulo 187
Los Angeles 143
Nuremberg 106
Rome 91
Boardman 83
Helsinki 83
Rio de Janeiro 83
Santa Clara 77
Orem 66
Tokyo 66
Dublin 58
Munich 58
Guangzhou 54
London 53
Da Nang 51
Belo Horizonte 47
Vienna 47
Denver 46
Montreal 45
Brasília 44
Brooklyn 44
Haiphong 41
Johannesburg 41
Quito 41
Warsaw 41
Chennai 40
Washington 39
Guayaquil 37
Phoenix 36
Stockholm 35
Council Bluffs 34
Turku 34
Frankfurt am Main 33
Brescia 32
Manchester 32
Mexico City 32
Poplar 32
Tashkent 31
Boston 30
Atlanta 29
Toronto 29
Amsterdam 28
Ankara 27
Hangzhou 27
Curitiba 26
Campinas 25
Houston 25
Porto Alegre 25
Shenzhen 25
The Dalles 25
Baghdad 24
Biên Hòa 24
Chicago 23
Pune 23
Salvador 23
Tianjin 23
Goiânia 22
Mumbai 22
San Francisco 20
Turin 20
Bologna 19
Dhaka 19
Hải Dương 19
Naples 19
Querétaro 19
Thái Bình 19
Manaus 18
Recife 18
Seattle 18
Buenos Aires 17
Buffalo 17
Caxias do Sul 17
Columbus 17
Fortaleza 17
Guarulhos 17
Jakarta 17
Lappeenranta 17
Santo André 17
Shijiazhuang 17
Can Tho 16
Montevideo 16
Nairobi 16
São Gonçalo 16
Betim 15
Totale 13.187
Salva come PNG Salva come JPEG
Nome #
CD4 CAR-T cells targeting CD19 play a key role in exacerbating cytokine release syndrome, while maintaining long-term responses 224
Rapamycin-Based GvHD Prophylaxis Is Effective in T-Cell Replete Unmanipulated Haploidentical Peripheral Stem Cell Transplantation for Advanced Haematological Malignancies: Results in 46 Patients 215
Immune Effector Cell-Associated Hematotoxicity (ICAHT): EHA/EBMT Consensus Grading and Best Practice Recommendations 214
Use of HSV-TK transduced donor lymphocytes in the context of allogeneic bone marrow transplantation: A paradigm of current applications and limitations in gene therapy 212
Loss of mismatched HLA in leukemia after stem-cell transplantation 200
Revealing and harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells 178
Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation 176
Dynamics of polyclonal immuno-reconstitution after allogeneic transplant with post-transplant cyclophosphamide and letermovir 167
A longitudinal analysis of humoral, T cellular response and influencing factors in a cohort of healthcare workers: Implications for personalized SARS-CoV-2 vaccination strategies 166
Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study 166
Clinical impact of suicide gene therapy in allogeneic hematopoietic stem cell transplantation 163
Blockade of αvβ6 and αvβ8 integrins with a chromogranin A-derived peptide inhibits TGFβ activation in tumors and suppresses tumor growth 163
Case report: Ponatinib as a bridge to CAR-T cells and subsequent maintenance in a patient with relapsed/refractory Philadelphia-like acute lymphoblastic leukemia 155
Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies 155
Systemic delivery of cadherin 17–specific CAR T cells allows effective and safe targeting of colorectal cancer liver metastases 149
CRISPR-based gene disruption and integration of high-avidity, WT1-specific T cell receptors improve antitumor T cell function 148
Biobanking for COVID-19 research 145
Epithelial ovarian cancer is infiltrated by activated effector T cells co-expressing CD39, PD-1, TIM-3, CD137 and interacting with cancer cells and myeloid cells 144
Case Report: Favorable outcome of allogeneic hematopoietic stem cell transplantation in SARSCoV2 positive recipient, risk-benefit balance between infection and leukemia 143
A clinical protocol for gene transfer into peripheral blood lymphocytes for in vivo immunomodulation of donor anti-tumor immunity in patients affected by recurrent disease after allogeneic bone marrow transplantation 139
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors 139
TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells 137
A CD8α− Subset of CD4+SLAMF7+ Cytotoxic T Cells Is Expanded in Patients With IgG4-Related Disease and Decreases Following Glucocorticoid Treatment 137
Regulatory T cells expressing CD19-targeted chimeric antigen receptor restore homeostasis in Systemic Lupus Erythematosus 133
Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation 131
Fat-to-blood recirculation of partially dysfunctional PD-1+CD4 Tconv cells is associated with dysglycemia in human obesity 125
Cytomegalovirus-specific T cells restricted for shared and donor human leukocyte antigens differentially impact on Cytomegalovirus reactivation risk after allogeneichematopoietic stem cell transplantation 125
A T cell epitope encoded by a subset HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation 123
A humanized Fas receptor-based suicide switch expressed in human T lymphocytes for the induction of controlled graft versus leukemia. 121
A phase II multicenter trial of HSV-TK engineered donor lymphocytes after haplo-identical HSCT: Early immune reconstitution and abrogation of GvHD 120
Unconventional CD147-dependent platelet activation elicited by SARS-CoV-2 in COVID-19 120
Adoptive immunotherapy with genetically modified lymphocytes in allogeneic stem cell transplantation 119
NON-GENOMIC ALTERATIONS IN ANTIGEN PRESENTATION AND T CELL COSTIMULATION ARE DISTINCT DRIVERS OF LEUKEMIA IMMUNE ESCAPE AND RELAPSE AFTER HEMATOPOIETIC CELL TRANSPLANTATION 118
Expression of inducible factors reprograms CAR-T cells for enhanced function and safety 118
MODELING ADOPTIVE IMMUNOTHERAPY IN MOUSE-HUMANS CHIMERAS TO IDENTIFY NOVEL MECHANISMS OF LEUKEMIA IMMUNOEDITING 117
A novel self-lipid antigen targets human T cells against CD1c(+) leukemias 116
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer 116
Erratum: Author Correction: Metabolic reprogramming of naïve regulatory T cells by IL-7 and IL-15 promotes their persistence and performance upon adoptive transfer (Communications biology (2025) 8 1 DOI: 10.1038/s42003-024-07381-1.) 115
CAR T cell manufacturing from naive/stem memory T lymphocytes enhances antitumor responses while curtailing cytokine release syndrome 115
CD4+ Memory Stem T Cells Recognizing Citrullinated Epitopes Are Expanded in Patients With Rheumatoid Arthritis and Sensitive to Tumor Necrosis Factor Blockade 114
A dual role for genetically modified lymphocytes in cancer immunotherapy 112
T cells for suicide gene therapy: Activation, functionality and clinical relevance 111
Immune Reconstitution-Based Score for Risk Stratification of Chronic Graft-Versus-Host Disease Patients 111
Allogeneic hematopoietic stem cell transplantation for neuromyelitis optica. 110
A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR 107
CRISPR/CAS9-BASED GENOME EDITING TO MODEL THE ANTI-LEUKEMIA IMMUNE RESPONSE AND IDENTIFY ITS MOLECULAR PLAYERS 106
819. Molecular Follow-Up of Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation and Donor Lymphocytes Transduced with a Retroviral Vector Expressing HSV-TK and ∆LNGFR 106
Anti-SARS-CoV-2 T-stem cell memory persists in ocrelizumab-treated MS patients 105
Harnessing CD39 for the Treatment of Colorectal Cancer and Liver Metastases by Engineered T Cells 105
Human herpesvirus 6-specific T-cell immunity in allogeneic hematopoietic stem cell transplant recipients 105
Allogeneic haematopoietic stem cell transplantation in refractory neuromyelitis optica spectrum disorders 104
A novel immunopeptidomic-based pipeline for the generation of personalized oncolytic cancer vaccines 104
CXCL10 levels at hospital admission predict COVID-19 outcome: hierarchical assessment of 53 putative inflammatory biomarkers in an observational study 103
Workflow for high-dimensional flow cytometry analysis of T cells from tumor metastases 103
A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease 102
Antitumor effects of HSV-TK-engineered donor lymphocytes after allogeneic stem-cell transplantation 101
IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer 101
Harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells 100
Leukemic blasts secondary to myelodysplastic syndromes are molecularly programmed to differentiate into functionally mature dendritic cells 99
A new suicide system based on gene transfer of FAS into donor lymphocytes for controlled GVL. 99
Posttransplantation Cyclophosphamide- and Sirolimus-Based Graft-Versus-Host-Disease Prophylaxis in Allogeneic Stem Cell Transplant 98
Graft-versus leukemia effect of HLA-haploidentical central-memory T cells expanded with leukemic APCs and modified with a suicide gene 97
Interleukin-7 improves the fitness of regulatory T cells for adoptive transfer 96
Adoptive T-cell therapy for cancer: The era of engineered T cells 94
TCR Redirected T Cells for Cancer Treatment: Achievements, Hurdles, and Goals 94
HARNESSING CD39 FOR THE TREATMENT OF COLORECTAL CANCER AND LIVER METASTASES BY ENGINEERED T CELLS 93
Combining Site-Specific Integration and Cassette Design to Achieve Robust Expression Without Impacting Endogenous Gene Expression 93
Abrogation of GvHD and early immune reconstitution after infusion of HSV-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation. 92
A model system for functional evaluation of isolated MHC disparities 92
Flow cytometry data mining by cytoChain identifies determinants of exhaustion and stemness in TCR-engineered T cells 92
T-N/SCM Pre-Selection Generates CAR T Cell Products Driving Superior Anti-Tumor Responses While Curtailing Severe CRS 91
A strategy for introducing and targeting antigen in activated dendritic cells for simultaneous stimulation of CD4 and CD8 cells. 91
Beneficial role of CD8+ T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias: results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting 91
The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies 91
A pilot study of HSV-TK gene transfer into donor peripheral blood lymphocytes for controlled GVL after allo-BMT. 90
Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation 90
Application of Donor Lymphocytes Expressing a Suicide Gene for Early GvL Induction and Later Control of GvH reactions after Bone Marrow Tranaplantation 89
Acute Myeloid Leukemia Relapses after Allogenenic HSCT Display a Distinctive Immune-Related Signature, with Frequent and Functionally Relevant Alterations in HLA Class II Antigen Presentation and T Cell Costimulation 89
CD4 CAR T Cells Drive Extensive CD8 CAR T Cell Expansion, Leading to Severe Cytokine Release Syndrome 88
Combining Targeted Integration and Cassette Design for Robust and Benign Transgene Expression without Impacting Endogenous Gene Transcription 88
N-Glycosylation Inhibition Hinders Immunosuppressive Activity of Tumor Microenvironment Cells and Improves CAR T Cell Efficacy 88
Metabolic reprogramming of naïve regulatory T cells by IL-7 and IL-15 promotes their persistence and performance upon adoptive transfer 87
CMV-specific T Cell Counts Early after Allogeneic Hematopoietic Stem Cell Transplantation Stratify the Risk of Subsequent CMV Reactivations: Results of a Prospective Observational Study 87
An Accelerated CD8+, but Not CD4+, T-Cell Reconstitution Associates with a More Favorable Outcome Following HLA-Haploidentical HSCT: Results from a Retrospective Study of the Cell Therapy and Immunobiology Working Party of the EBMT 87
Enhancing anti-tumour efficacy with immunotherapy combinations 86
Human T cells engineered with a leukemia lipid-specific TCR enables donor-unrestricted recognition of CD1c-expressing leukemia 86
Harnessing the tumor microenvironment to boost adoptive T cell therapy with engineered lymphocytes for solid tumors 85
Alterations in the genomic and transcriptional profile of leukemia upon the immune pressure of allogenic hematopoietic stem cell transplantation: tracking immunoediting by high-throughput techniques 85
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells 85
An Accelerated CD8+, but Not CD4+, T -Cell Reconstitution Associates with a More Favorable Outcome Following HLA-Haploidentical HSCT: Results from a Retrospective Study of the Cell Therapy and Immunobiology Working Party of the EBMT 84
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory 83
Early and Effective Immune-Recovery by Gene-Engineered Lymphocytes after Haploidentical Transplantation for Leukemia Abate Late Transplant Mortality 83
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 83
Role of HLA-B exon 1 in graft-versus-host disease after unrelated haemopoietic cell transplantation: a retrospective cohort study 83
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 80
AN INNOVATIVE HUMANIZED MOUSE MODEL TO INVESTIGATE THE INTERPLAY BETWEEN IMMUNE SYSTEM AND ACUTE MYELOID LEUKEMIA IN ALLOGENEIC HSCT 80
Epigenetic checkpoints regulate the fate and function of CAR-T cells 79
Autoantibody Production during Chronic Graft-Versus-Host Disease Does Not Associate with Long-Term Persistence of Host B Cells in Humans 79
NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease 79
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 78
Totale 11.481
Salva come PNG Salva come JPEG
Categoria #
all - tutte 190.959
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 190.959
Salva come PNG Salva come JPEG


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022278 0 0 0 125 25 7 18 34 13 23 7 26
2022/20232.256 918 480 124 22 55 256 84 124 96 28 50 19
2023/20241.308 51 58 140 129 118 240 156 99 21 53 62 181
2024/20256.305 728 106 99 183 168 479 751 553 1.100 889 600 649
2025/202618.663 1.376 1.517 1.514 2.930 1.380 562 1.488 1.290 4.972 836 481 317
Totale 29.005