IRIS
BONINI, MARIA CHIARA
 Distribuzione geografica
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Continente #
AS - Asia 9.676
EU - Europa 9.342
NA - Nord America 5.466
SA - Sud America 2.851
AF - Africa 218
OC - Oceania 25
Continente sconosciuto - Info sul continente non disponibili 4
Totale 27.582
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Nazione #
RU - Federazione Russa 5.497
US - Stati Uniti d'America 5.190
SG - Singapore 3.747
CN - Cina 2.766
BR - Brasile 2.333
HK - Hong Kong 1.262
SE - Svezia 1.139
IT - Italia 1.037
VN - Vietnam 1.010
FR - Francia 477
DE - Germania 362
AR - Argentina 202
GB - Regno Unito 184
IN - India 172
FI - Finlandia 135
BD - Bangladesh 114
EC - Ecuador 114
CA - Canada 110
JP - Giappone 107
MX - Messico 97
AT - Austria 96
NL - Olanda 96
ID - Indonesia 87
ZA - Sudafrica 73
TR - Turchia 65
IE - Irlanda 63
IQ - Iraq 62
CO - Colombia 61
ES - Italia 56
PY - Paraguay 50
PL - Polonia 49
PK - Pakistan 36
MA - Marocco 33
SA - Arabia Saudita 33
UZ - Uzbekistan 33
UA - Ucraina 28
VE - Venezuela 27
TN - Tunisia 26
CL - Cile 24
DZ - Algeria 22
EG - Egitto 20
AU - Australia 19
UY - Uruguay 19
PH - Filippine 18
CH - Svizzera 17
IL - Israele 16
KE - Kenya 16
BE - Belgio 15
LT - Lituania 15
PE - Perù 14
DO - Repubblica Dominicana 13
MY - Malesia 13
IR - Iran 12
KR - Corea 12
JM - Giamaica 11
CR - Costa Rica 10
LB - Libano 10
AE - Emirati Arabi Uniti 9
JO - Giordania 9
NP - Nepal 8
TH - Thailandia 8
BB - Barbados 7
BY - Bielorussia 7
DK - Danimarca 7
PT - Portogallo 7
TW - Taiwan 7
AL - Albania 6
AM - Armenia 6
CI - Costa d'Avorio 6
KW - Kuwait 6
NZ - Nuova Zelanda 6
SY - Repubblica araba siriana 6
AZ - Azerbaigian 5
GE - Georgia 5
GT - Guatemala 5
HU - Ungheria 5
KG - Kirghizistan 5
KZ - Kazakistan 5
MD - Moldavia 5
OM - Oman 5
RS - Serbia 5
TT - Trinidad e Tobago 5
BA - Bosnia-Erzegovina 4
BO - Bolivia 4
CY - Cipro 4
CZ - Repubblica Ceca 4
GR - Grecia 4
KH - Cambogia 4
MK - Macedonia 4
PA - Panama 4
PS - Palestinian Territory 4
SK - Slovacchia (Repubblica Slovacca) 4
AO - Angola 3
BG - Bulgaria 3
DM - Dominica 3
ET - Etiopia 3
GH - Ghana 3
HN - Honduras 3
RO - Romania 3
SC - Seychelles 3
Totale 27.544
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Città #
Singapore 1.503
Moscow 1.208
Hong Kong 1.184
Ashburn 791
Dallas 782
San Jose 585
Shanghai 554
Hefei 462
Lawrence 409
Princeton 409
Lauterbourg 392
Ho Chi Minh City 390
Milan 334
Beijing 314
New York 255
Hanoi 194
São Paulo 185
Los Angeles 130
Nuremberg 106
Boardman 83
Helsinki 83
Rio de Janeiro 83
Rome 80
Tokyo 66
Orem 62
Munich 58
Dublin 57
Santa Clara 56
Da Nang 51
Guangzhou 51
Belo Horizonte 47
Vienna 47
Brasília 44
Denver 43
Montreal 43
Brooklyn 42
Johannesburg 41
Quito 41
Warsaw 41
Chennai 40
Haiphong 40
Guayaquil 37
Washington 36
Stockholm 35
Turku 34
Frankfurt am Main 33
Phoenix 33
Council Bluffs 32
Poplar 32
Brescia 31
Tashkent 31
Boston 30
London 30
Manchester 29
Amsterdam 28
Ankara 27
Mexico City 27
Atlanta 26
Curitiba 26
Campinas 25
Porto Alegre 25
Shenzhen 25
Baghdad 24
Biên Hòa 24
Hangzhou 24
Houston 24
Toronto 24
Pune 23
Salvador 23
The Dalles 23
Goiânia 22
Mumbai 22
Chicago 21
Tianjin 21
Turin 20
Dhaka 19
Hải Dương 19
Querétaro 19
Thái Bình 19
Bologna 18
Manaus 18
Recife 18
Seattle 18
Buenos Aires 17
Caxias do Sul 17
Fortaleza 17
Guarulhos 17
Jakarta 17
Lappeenranta 17
Santo André 17
Shijiazhuang 17
Can Tho 16
Montevideo 16
Nairobi 16
Naples 16
São Gonçalo 16
Betim 15
Joinville 15
Montes Claros 15
Asunción 14
Totale 12.736
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Nome #
CD4 CAR-T cells targeting CD19 play a key role in exacerbating cytokine release syndrome, while maintaining long-term responses 217
Rapamycin-Based GvHD Prophylaxis Is Effective in T-Cell Replete Unmanipulated Haploidentical Peripheral Stem Cell Transplantation for Advanced Haematological Malignancies: Results in 46 Patients 213
Use of HSV-TK transduced donor lymphocytes in the context of allogeneic bone marrow transplantation: A paradigm of current applications and limitations in gene therapy 212
Immune Effector Cell-Associated Hematotoxicity (ICAHT): EHA/EBMT Consensus Grading and Best Practice Recommendations 187
Loss of mismatched HLA in leukemia after stem-cell transplantation 182
Revealing and harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells 171
Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation 161
Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study 161
Dynamics of polyclonal immuno-reconstitution after allogeneic transplant with post-transplant cyclophosphamide and letermovir 160
A longitudinal analysis of humoral, T cellular response and influencing factors in a cohort of healthcare workers: Implications for personalized SARS-CoV-2 vaccination strategies 160
Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies 151
Case report: Ponatinib as a bridge to CAR-T cells and subsequent maintenance in a patient with relapsed/refractory Philadelphia-like acute lymphoblastic leukemia 148
Clinical impact of suicide gene therapy in allogeneic hematopoietic stem cell transplantation 146
Biobanking for COVID-19 research 144
Systemic delivery of cadherin 17–specific CAR T cells allows effective and safe targeting of colorectal cancer liver metastases 142
CRISPR-based gene disruption and integration of high-avidity, WT1-specific T cell receptors improve antitumor T cell function 140
Epithelial ovarian cancer is infiltrated by activated effector T cells co-expressing CD39, PD-1, TIM-3, CD137 and interacting with cancer cells and myeloid cells 138
Case Report: Favorable outcome of allogeneic hematopoietic stem cell transplantation in SARSCoV2 positive recipient, risk-benefit balance between infection and leukemia 136
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors 134
A clinical protocol for gene transfer into peripheral blood lymphocytes for in vivo immunomodulation of donor anti-tumor immunity in patients affected by recurrent disease after allogeneic bone marrow transplantation 133
A CD8α− Subset of CD4+SLAMF7+ Cytotoxic T Cells Is Expanded in Patients With IgG4-Related Disease and Decreases Following Glucocorticoid Treatment 133
TIM-3, LAG-3, or 2B4 gene disruptions increase the anti-tumor response of engineered T cells 132
Regulatory T cells expressing CD19-targeted chimeric antigen receptor restore homeostasis in Systemic Lupus Erythematosus 125
Fat-to-blood recirculation of partially dysfunctional PD-1+CD4 Tconv cells is associated with dysglycemia in human obesity 123
Cytomegalovirus-specific T cells restricted for shared and donor human leukocyte antigens differentially impact on Cytomegalovirus reactivation risk after allogeneichematopoietic stem cell transplantation 123
Blockade of αvβ6 and αvβ8 integrins with a chromogranin A-derived peptide inhibits TGFβ activation in tumors and suppresses tumor growth 123
A T cell epitope encoded by a subset HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation 120
A humanized Fas receptor-based suicide switch expressed in human T lymphocytes for the induction of controlled graft versus leukemia. 119
Unconventional CD147-dependent platelet activation elicited by SARS-CoV-2 in COVID-19 119
Expression of inducible factors reprograms CAR-T cells for enhanced function and safety 117
A phase II multicenter trial of HSV-TK engineered donor lymphocytes after haplo-identical HSCT: Early immune reconstitution and abrogation of GvHD 117
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer 116
A novel self-lipid antigen targets human T cells against CD1c(+) leukemias 115
MODELING ADOPTIVE IMMUNOTHERAPY IN MOUSE-HUMANS CHIMERAS TO IDENTIFY NOVEL MECHANISMS OF LEUKEMIA IMMUNOEDITING 115
Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation 113
NON-GENOMIC ALTERATIONS IN ANTIGEN PRESENTATION AND T CELL COSTIMULATION ARE DISTINCT DRIVERS OF LEUKEMIA IMMUNE ESCAPE AND RELAPSE AFTER HEMATOPOIETIC CELL TRANSPLANTATION 111
A dual role for genetically modified lymphocytes in cancer immunotherapy 110
CD4+ Memory Stem T Cells Recognizing Citrullinated Epitopes Are Expanded in Patients With Rheumatoid Arthritis and Sensitive to Tumor Necrosis Factor Blockade 109
CAR T cell manufacturing from naive/stem memory T lymphocytes enhances antitumor responses while curtailing cytokine release syndrome 108
Allogeneic hematopoietic stem cell transplantation for neuromyelitis optica. 108
Human herpesvirus 6-specific T-cell immunity in allogeneic hematopoietic stem cell transplant recipients 104
Immune Reconstitution-Based Score for Risk Stratification of Chronic Graft-Versus-Host Disease Patients 104
A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR 103
CRISPR/CAS9-BASED GENOME EDITING TO MODEL THE ANTI-LEUKEMIA IMMUNE RESPONSE AND IDENTIFY ITS MOLECULAR PLAYERS 102
Harnessing CD39 for the Treatment of Colorectal Cancer and Liver Metastases by Engineered T Cells 102
Adoptive immunotherapy with genetically modified lymphocytes in allogeneic stem cell transplantation 102
Allogeneic haematopoietic stem cell transplantation in refractory neuromyelitis optica spectrum disorders 101
Workflow for high-dimensional flow cytometry analysis of T cells from tumor metastases 101
A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease 100
CXCL10 levels at hospital admission predict COVID-19 outcome: hierarchical assessment of 53 putative inflammatory biomarkers in an observational study 99
IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer 99
A new suicide system based on gene transfer of FAS into donor lymphocytes for controlled GVL. 98
T cells for suicide gene therapy: Activation, functionality and clinical relevance 97
Harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells 97
Erratum: Author Correction: Metabolic reprogramming of naïve regulatory T cells by IL-7 and IL-15 promotes their persistence and performance upon adoptive transfer (Communications biology (2025) 8 1 DOI: 10.1038/s42003-024-07381-1.) 96
Graft-versus leukemia effect of HLA-haploidentical central-memory T cells expanded with leukemic APCs and modified with a suicide gene 96
Leukemic blasts secondary to myelodysplastic syndromes are molecularly programmed to differentiate into functionally mature dendritic cells 95
819. Molecular Follow-Up of Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation and Donor Lymphocytes Transduced with a Retroviral Vector Expressing HSV-TK and ∆LNGFR 95
Anti-SARS-CoV-2 T-stem cell memory persists in ocrelizumab-treated MS patients 94
Interleukin-7 improves the fitness of regulatory T cells for adoptive transfer 93
Adoptive T-cell therapy for cancer: The era of engineered T cells 92
Combining Site-Specific Integration and Cassette Design to Achieve Robust Expression Without Impacting Endogenous Gene Expression 92
TCR Redirected T Cells for Cancer Treatment: Achievements, Hurdles, and Goals 92
HARNESSING CD39 FOR THE TREATMENT OF COLORECTAL CANCER AND LIVER METASTASES BY ENGINEERED T CELLS 91
A model system for functional evaluation of isolated MHC disparities 91
Beneficial role of CD8+ T-cell reconstitution after HLA-haploidentical stem cell transplantation for high-risk acute leukaemias: results from a clinico-biological EBMT registry study mostly in the T-cell-depleted setting 91
Flow cytometry data mining by cytoChain identifies determinants of exhaustion and stemness in TCR-engineered T cells 91
A novel immunopeptidomic-based pipeline for the generation of personalized oncolytic cancer vaccines 90
T-N/SCM Pre-Selection Generates CAR T Cell Products Driving Superior Anti-Tumor Responses While Curtailing Severe CRS 89
Abrogation of GvHD and early immune reconstitution after infusion of HSV-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation. 89
A strategy for introducing and targeting antigen in activated dendritic cells for simultaneous stimulation of CD4 and CD8 cells. 89
A pilot study of HSV-TK gene transfer into donor peripheral blood lymphocytes for controlled GVL after allo-BMT. 88
Application of Donor Lymphocytes Expressing a Suicide Gene for Early GvL Induction and Later Control of GvH reactions after Bone Marrow Tranaplantation 88
Acute Myeloid Leukemia Relapses after Allogenenic HSCT Display a Distinctive Immune-Related Signature, with Frequent and Functionally Relevant Alterations in HLA Class II Antigen Presentation and T Cell Costimulation 88
Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation 87
N-Glycosylation Inhibition Hinders Immunosuppressive Activity of Tumor Microenvironment Cells and Improves CAR T Cell Efficacy 87
CD4 CAR T Cells Drive Extensive CD8 CAR T Cell Expansion, Leading to Severe Cytokine Release Syndrome 86
Combining Targeted Integration and Cassette Design for Robust and Benign Transgene Expression without Impacting Endogenous Gene Transcription 86
CMV-specific T Cell Counts Early after Allogeneic Hematopoietic Stem Cell Transplantation Stratify the Risk of Subsequent CMV Reactivations: Results of a Prospective Observational Study 85
Antitumor effects of HSV-TK-engineered donor lymphocytes after allogeneic stem-cell transplantation 85
Alterations in the genomic and transcriptional profile of leukemia upon the immune pressure of allogenic hematopoietic stem cell transplantation: tracking immunoediting by high-throughput techniques 85
Posttransplantation Cyclophosphamide- and Sirolimus-Based Graft-Versus-Host-Disease Prophylaxis in Allogeneic Stem Cell Transplant 85
An Accelerated CD8+, but Not CD4+, T-Cell Reconstitution Associates with a More Favorable Outcome Following HLA-Haploidentical HSCT: Results from a Retrospective Study of the Cell Therapy and Immunobiology Working Party of the EBMT 84
Human T cells engineered with a leukemia lipid-specific TCR enables donor-unrestricted recognition of CD1c-expressing leukemia 84
An Accelerated CD8+, but Not CD4+, T -Cell Reconstitution Associates with a More Favorable Outcome Following HLA-Haploidentical HSCT: Results from a Retrospective Study of the Cell Therapy and Immunobiology Working Party of the EBMT 83
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 82
Harnessing the tumor microenvironment to boost adoptive T cell therapy with engineered lymphocytes for solid tumors 80
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory 80
AN INNOVATIVE HUMANIZED MOUSE MODEL TO INVESTIGATE THE INTERPLAY BETWEEN IMMUNE SYSTEM AND ACUTE MYELOID LEUKEMIA IN ALLOGENEIC HSCT 80
Enhancing anti-tumour efficacy with immunotherapy combinations 80
Epigenetic checkpoints regulate the fate and function of CAR-T cells 78
Autoantibody Production during Chronic Graft-Versus-Host Disease Does Not Associate with Long-Term Persistence of Host B Cells in Humans 78
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 78
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 77
NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease 77
Th22 cells increase in poor prognosis multiple myeloma and promote tumor cell growth and survival 75
Sorafenib promotes graft-versus-leukemia activity in mice and humans through IL-15 production in FLT3-ITD-mutant leukemia cells 75
ALLOGENEIC STEM CELL TRANSPLANTATION FOR HEMATOLOGIC MALIGNANCIES: 4GY TBI TO INTENSIFY TREOSULFAN AND FLUDARABINE-BASED CONDITIONING 75
Herpes simplex virus thymidine kinase gene transfer for controlled graft-versus-host disease and graft-versus-leukemia: Clinical follow-up and improved new vectors 74
Erratum: Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory (Science Translational Medicine (2015) 7:319 (319er9)) 74
Totale 10.931
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Categoria #
all - tutte 178.242
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 178.242
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2021/2022278 0 0 0 125 25 7 18 34 13 23 7 26
2022/20232.256 918 480 124 22 55 256 84 124 96 28 50 19
2023/20241.308 51 58 140 129 118 240 156 99 21 53 62 181
2024/20256.305 728 106 99 183 168 479 751 553 1.100 889 600 649
2025/202617.614 1.376 1.517 1.514 2.930 1.380 562 1.488 1.290 4.972 585 0 0
Totale 27.956