IRIS
BONINI, MARIA CHIARA
 Distribuzione geografica
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Continente #
EU - Europa 1.644
NA - Nord America 1.560
AS - Asia 310
OC - Oceania 11
SA - Sud America 10
AF - Africa 5
Totale 3.540
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Nazione #
US - Stati Uniti d'America 1.541
SE - Svezia 1.102
IT - Italia 300
CN - Cina 94
FI - Finlandia 72
HK - Hong Kong 72
IE - Irlanda 52
DE - Germania 51
JP - Giappone 51
IN - India 35
GB - Regno Unito 20
SA - Arabia Saudita 15
SG - Singapore 13
FR - Francia 12
CA - Canada 11
IL - Israele 11
IR - Iran 8
RU - Federazione Russa 7
AT - Austria 6
BR - Brasile 6
NZ - Nuova Zelanda 6
AU - Australia 5
CH - Svizzera 5
DO - Repubblica Dominicana 5
ES - Italia 5
AR - Argentina 4
NL - Olanda 4
TH - Thailandia 4
DK - Danimarca 3
MX - Messico 3
TW - Taiwan 3
BE - Belgio 2
DZ - Algeria 2
EG - Egitto 2
KR - Corea 2
IQ - Iraq 1
LU - Lussemburgo 1
MG - Madagascar 1
MK - Macedonia 1
PK - Pakistan 1
UA - Ucraina 1
Totale 3.540
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Città #
Lawrence 410
Princeton 410
Ashburn 189
New York 136
Milan 125
Helsinki 72
Shanghai 58
Dublin 49
Washington 29
Pune 19
Rome 19
Los Angeles 14
Seattle 13
Tokyo 11
Borås 10
Hanover 8
Brescia 7
Rockville 7
San Jose 6
Shijiazhuang 6
Turin 6
Andover 5
Cotui 5
Falls Church 5
Jeddah 5
Overland Park 5
Acton 4
Al Qatif 4
Bangkok 4
Beijing 4
Boardman 4
Bologna 4
Cambridge 4
Hong Kong 4
Hyderabad 4
Moreno Valley 4
Mountain View 4
Redwood City 4
Santa Clara 4
Toronto 4
Vauderens 4
Aci Sant'Antonio 3
Ballincollig 3
Boston 3
Busto Arsizio 3
Cantù 3
Chapel Hill 3
Chiyoda-ku 3
Florence 3
Genoa 3
Hadera 3
Ibaraki 3
Iowa City 3
Kfar Saba 3
Monrovia 3
Oberndorf bei Salzburg 3
Osimo 3
Paris 3
Pavia 3
Philadelphia 3
Phoenix 3
Pomona 3
Riyadh 3
Segrate 3
St Louis 3
St Petersburg 3
Zhengzhou 3
Albairate 2
Albuquerque 2
Avellino 2
Barcelona 2
Baronissi 2
Birmingham 2
Bordeaux 2
Brembate di Sopra 2
Buenos Aires 2
Burnaby 2
Burolo 2
Cagliari 2
Castelli Calepio 2
Castelseprio 2
Castenaso 2
Central 2
Chaoyang 2
Cittadella 2
Copenhagen 2
Dalmine 2
Ekimaedori 2
Falkenstein 2
Ferrara 2
Galliate 2
Gangnam-gu 2
Ghent 2
Gorgonzola 2
Haifa 2
Harrow 2
Inman 2
Innsbruck 2
Kolkata 2
Kunming 2
Totale 1.833
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Nome #
CD4 CAR-T cells targeting CD19 play a key role in exacerbating cytokine release syndrome, while maintaining long-term responses 99
MODELING ADOPTIVE IMMUNOTHERAPY IN MOUSE-HUMANS CHIMERAS TO IDENTIFY NOVEL MECHANISMS OF LEUKEMIA IMMUNOEDITING 68
Infusion of suicide-gene-engineered donor lymphocytes after family haploidentical haemopoietic stem-cell transplantation for leukaemia (the TK007 trial): a non-randomised phase I-II study 58
Clinical impact of suicide gene therapy in allogeneic hematopoietic stem cell transplantation 51
Incidence, risk factors and clinical outcome of leukemia relapses with loss of the mismatched HLA after partially incompatible hematopoietic stem cell transplantation 34
Case report: Ponatinib as a bridge to CAR-T cells and subsequent maintenance in a patient with relapsed/refractory Philadelphia-like acute lymphoblastic leukemia 33
Revealing and harnessing CD39 for the treatment of colorectal cancer and liver metastases by engineered T cells 29
A clinical protocol for gene transfer into peripheral blood lymphocytes for in vivo immunomodulation of donor anti-tumor immunity in patients affected by recurrent disease after allogeneic bone marrow transplantation 28
Sirolimus-based graft-versus-host disease prophylaxis promotes the in vivo expansion of regulatory T cells and permits peripheral blood stem cell transplantation from haploidentical donors 27
CRISPR-based gene disruption and integration of high-avidity, WT1-specific T cell receptors improve antitumor T cell function 27
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer 26
Transfer of the HSV-tk gene into donor peripheral blood lymphocytes for in vivo modulation of donor anti-tumor immunity after allogeneic bone marrow transplantation 25
Biobanking for COVID-19 research 25
Unconventional CD147-dependent platelet activation elicited by SARS-CoV-2 in COVID-19 25
Immunoediting of the genomic and transcriptional profile of acute myeloid leukaemia in response to allogeneic haematopoietic stem cell transplantation 24
Disrupting N-glycan expression on tumor cells boosts chimeric antigen receptor T cell efficacy against solid malignancies 23
Site-specific integration and tailoring of cassette design for sustainable gene transfer 22
Immune Reconstitution-Based Score for Risk Stratification of Chronic Graft-Versus-Host Disease Patients 22
FAS-based suicide gene strategy for controlled GvHD: An alternative to HSV-tk. 21
A longitudinal analysis of humoral, T cellular response and influencing factors in a cohort of healthcare workers: Implications for personalized SARS-CoV-2 vaccination strategies 20
Abrogation of GvHD and early immune reconstitution after infusion of HSV-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation. 20
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory 20
Posttransplantation Cyclophosphamide- and Sirolimus-Based Graft-Versus-Host-Disease Prophylaxis in Allogeneic Stem Cell Transplant 20
A humanized Fas receptor-based suicide switch expressed in human T lymphocytes for the induction of controlled graft versus leukemia. 19
Allogeneic hematopoietic stem cell transplantation for neuromyelitis optica. 19
Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation 19
CD4+ Memory Stem T Cells Recognizing Citrullinated Epitopes Are Expanded in Patients With Rheumatoid Arthritis and Sensitive to Tumor Necrosis Factor Blockade 19
A new suicide system based on gene transfer of FAS into donor lymphocytes for controlled GVL. 18
In-vivo T-regs generation by rapamycin-mycophenolate-ATG as a new platform for GvHD prophylaxis in T-cell repleted unmanipulated haploidentical peripheral stem cell transplantation: results in 59 patients 18
CRISPR/CAS9-BASED GENOME EDITING TO MODEL THE ANTI-LEUKEMIA IMMUNE RESPONSE AND IDENTIFY ITS MOLECULAR PLAYERS 17
Infusion of HSV-tk genetically-engineered donor lymphocytes restores anti-viral immunity early after allogeneic BMT. 17
A CD8α− Subset of CD4+SLAMF7+ Cytotoxic T Cells Is Expanded in Patients With IgG4-Related Disease and Decreases Following Glucocorticoid Treatment 17
CXCL10 levels at hospital admission predict COVID-19 outcome: hierarchical assessment of 53 putative inflammatory biomarkers in an observational study 17
A novel immunopeptidomic-based pipeline for the generation of personalized oncolytic cancer vaccines 17
Dynamics of polyclonal immuno-reconstitution after allogeneic transplant with post-transplant cyclophosphamide and letermovir 16
Expression of inducible factors reprograms CAR-T cells for enhanced function and safety 16
Suicide gene transduced for the regulation of the graft-versus-leukemia effect 16
A Fas-based suicide switch in human T cells for the treatment of graft-versus-host disease 16
Adoptive immunotherapy with genetically modified lymphocytes in allogeneic stem cell transplantation 16
819. Molecular Follow-Up of Patients Treated with Allogeneic Hematopoietic Stem Cell Transplantation and Donor Lymphocytes Transduced with a Retroviral Vector Expressing HSV-TK and ∆LNGFR 16
From TCR Gene Transfer to TCR Gene Editing of Central Memory T Lymphocytes for Immunotherapy of Leukemia 16
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 16
T Cell Suicide Gene Therapy Prompts Thymic Renewal in Adults After Haploidentical Hematopoietic Stem Cell Transplantation in the Absence of Post-Transplant Immunesuppression 16
TCR gene editing results in effective immunotherapy of leukaemia without the development of GvHD 16
A phase II multicenter trial of HSV-TK engineered donor lymphocytes after haplo-identical HSCT: Early immune reconstitution and abrogation of GvHD 16
Clinical and molecular features associated with acute myeloid leukemia engraftment in immunodeficient mouse models 16
Anti-SARS-CoV-2 T-stem cell memory persists in ocrelizumab-treated MS patients 15
Herpes simplex virus thymidine kinase gene transfer for controlled graft-versus-host disease and graft-versus-leukemia: Clinical follow-up and improved new vectors 15
Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy 15
Loss of mismatched HLA in leukemia after stem-cell transplantation 15
A T cell epitope encoded by a subset HLA-DPB1 alleles determines nonpermissive mismatches for hematologic stem cell transplantation 15
Use of HSV-TK transduced donor lymphocytes in the context of allogeneic bone marrow transplantation: A paradigm of current applications and limitations in gene therapy 15
Immune monitoring in allogeneic hematopoietic stem cell transplant recipients: a survey from the EBMT-CTIWP 15
Flow cytometry data mining by cytoChain identifies determinants of exhaustion and stemness in TCR-engineered T cells 15
Time to evolve: predicting engineered T cell-associated toxicity with next-generation models 14
Case Report: Favorable outcome of allogeneic hematopoietic stem cell transplantation in SARSCoV2 positive recipient, risk-benefit balance between infection and leukemia 14
Targeted genome editing in human repopulating haematopoietic stem cells 14
A novel self-lipid antigen targets human T cells against CD1c(+) leukemias 14
Suicide gene transduced T-cells for the regulation of the graft-versus-leukemia effect 14
T Cell Receptor Gene Transfer into Early Differentiated Lymphocytes by Lentiviral Vectors for Safe and Effective Adoptive Immune Therapy of Leukemia 14
Allogeneic haematopoietic stem cell transplantation in refractory neuromyelitis optica spectrum disorders 14
Safety and Efficacy of Donor T Cells Engineered with Herpes Simplex Virus Thymidine-Kinase Suicide Gene (TK Cells) Given after T-Cell Depleted (TCD) Haploidentical Hematopoietic Transplantation (Haplo-HSCT): Results of a 14-Year Follow-Up in 45 Patients 13
Cytomegalovirus-specific T cells restricted for shared and donor human leukocyte antigens differentially impact on Cytomegalovirus reactivation risk after allogeneichematopoietic stem cell transplantation 13
T cells for suicide gene therapy: Activation, functionality and clinical relevance 13
Adoptive T-cell therapy for cancer: The era of engineered T cells 13
Reinfusion of Hsv-TK engineered donor lymphocytes after haplo-identical hemopoietic stem cell transplantation provide early immune reconstitution without GvHD. 13
Targeting Integration to Selected Genomic Loci and In Situ Tailoring of Cassette Design Allows Robust Transgene Expression without Perturbing Endogenous Transcription 13
A pilot study of HSV-TK gene transfer into donor peripheral blood lymphocytes for controlled GVL after allo-BMT. 13
Early molecular diagnosis of aspergillosis in a patient with acute myeloid leukaemia 13
Rapamycin-Based GvHD Prophylaxis Is Effective in T-Cell Replete Unmanipulated Haploidentical Peripheral Stem Cell Transplantation for Advanced Haematological Malignancies: Results in 46 Patients 13
Genomic typing for patient-specific human leukocyte antigen-alleles is an efficient tool for relapse detection of high-risk hematopoietic malignancies after stem cell transplantation from alternative donors 13
Human Herpesvirus 6 Infection Following Haploidentical Transplantation: Immune Recovery and Outcome 13
In vivo tracking of T cells in humans unveils decade-long survival and activity of genetically modified T memory stem cells 13
NY-ESO-1 TCR single edited stem and central memory T cells to treat multiple myeloma without graft-versus-host disease 13
Enhancing anti-tumour efficacy with immunotherapy combinations 13
Graft-versus leukemia effect of HLA-haploidentical central-memory T cells expanded with leukemic APCs and modified with a suicide gene 13
Peripheral blood lymphocytes as target cells of retroviral vector-mediated gene transfer 13
Transcriptional Enhancers Induce Insertional Gene Deregulation Independently From the Vector Type and Design 12
A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR 12
Leukemic blasts secondary to myelodysplastic syndromes are molecularly programmed to differentiate into functionally mature dendritic cells 12
Editing Human Lymphocyte Specificity for Safe and Effective Adoptive Immunotherapy of Leukemia 12
A dual role for genetically modified lymphocytes in cancer immunotherapy 12
Erratum: Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory (Science Translational Medicine (2015) 7:319 (319er9)) 12
T memory stem cells in health and disease 12
HSV-TK gene transfer into donor lymphocytes for control of allogeneic graft-versus-leukemia 12
Acute Myeloid Leukemia Relapses after Allogenenic HSCT Display a Distinctive Immune-Related Signature, with Frequent and Functionally Relevant Alterations in HLA Class II Antigen Presentation and T Cell Costimulation 12
The potential immunogenicity of the TK suicide gene does not prevent full clinical benefit associated with the use of TK-transduced donor lymphocytes in HSCT for hematologic malignancies 12
Human T cells engineered with a leukemia lipid-specific TCR enables donor-unrestricted recognition of CD1c-expressing leukemia 12
Interleukin-7 improves the fitness of regulatory T cells for adoptive transfer 12
Impact of Immune Reconstitution (IR) and Graft-Versus-Host Disease (GvHD) on Clinical Outcomes after Treatment with Donor T Cells Transduced to Express the Herpes Simplex Virus Thymidine-Kinase Suicide Gene (TK cells) in Acute Leukemia Patients Undergoing Haploidentical Hematopoietic Stem Cell Transplantation (HSCT) 11
CD4 CAR T Cells Drive Extensive CD8 CAR T Cell Expansion, Leading to Severe Cytokine Release Syndrome 11
Immune Effector Cell-Associated Hematotoxicity (ICAHT): EHA/EBMT Consensus Grading and Best Practice Recommendations 11
Retroviral vector integration deregulates gene expression but has no consequence on the biology and function of transplanted T cells 11
Rapid detection of all HLA-B*27 alleles (B*2701-B*2725) by group-specific polymerase chain reaction 11
Programmed infusions of Tk-transduced donor lymphocytes for immune reconstitution and relapse prevention in haplo-identical T-depleted SCT. 11
Long term follow-up in 30 patients receiving HSV-TK transduced donor lymphocytes after allo-BMT. 11
Improving the safety of cell therapy with the TK-suicide gene. 11
Antitumor effects of HSV-TK-engineered donor lymphocytes after allogeneic stem-cell transplantation 11
Alterations in the genomic and transcriptional profile of leukemia upon the immune pressure of allogenic hematopoietic stem cell transplantation: tracking immunoediting by high-throughput techniques 11
A model system for functional evaluation of isolated MHC disparities 11
Totale 1.827
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Categoria #
all - tutte 66.790
article - articoli 0
book - libri 0
conference - conferenze 0
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 66.790
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Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2019/202031 18 0 0 5 0 0 1 1 0 6 0 0
2020/202187 0 0 0 3 2 7 70 0 5 0 0 0
2021/2022278 0 0 0 125 25 7 18 34 13 23 7 26
2022/20232.263 922 482 124 22 55 257 84 124 96 28 50 19
2023/20241.067 51 58 141 130 122 240 156 99 21 49 0 0
Totale 3.803