Role of IPAA for Crohn's Disease

Proctocolectomy and creation of an ileal pouch-anal anastomosis (IPAA), first described by Parks and Nicholls, is the preferred and most commonly performed surgical procedure for patients requiring resection of the entire large intestine provided they demonstrate good sphincter function and lack risk factors for postoperative complications or dysfunction. The operation was initially developed for patients with ulcerative colitis or familial adenomatous polyposis to preserve the normal route of defecation and avoid the need for a permanent stoma while ensuring acceptable functional results and satisfactory patient-reported quality of life.