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1 Contributo su Rivista 33441

2 Contributo in Volume 2611

3 Libro 683
- 3.1 Monografia o trattato scientifico 554
- 3.2 Concordanza 0
- 3.3 Indice 5
- 3.4 Bibliografia 12
- 3.5 Edizione critica 24
- 3.6 Pubblicazione di fonti inedite 5
- 3.7 Commento scientifico 13
- 3.8 Traduzione di libro 70

4 Contributo in Atti di Convegno (Proceeding) 4191
- 4.1 Contributo in Atti di convegno 1571
- 4.2 Abstract in Atti di convegno 2287
- 4.3 Poster 333

5 Altro 89
- 5.01 Composizione 0
- 5.02 Disegno 0
- 5.03 Design 0
- 5.04 Performance 3
- 5.05 Esposizione 0
- 5.06 Mostra 0
- 5.07 Manufatto 1
- 5.08 Prototipo d'arte e relativi progetti 0
- 5.09 Cartografia 0
- 5.10 Banca dati 1
- 5.11 Software 12
- 5.12 Altro 72
- 5.13 Progetto architettonico 0

6 Brevetti 161
- 6.1 Brevetto 161

7 Curatele 161
- 7.1 Curatela 161

8 Tesi di dottorato 85
- 8.1 Tesi di dottorato 85

Prodotti recenti

10th National Congress of Medical Oncology

Concetti di pietra. Heidegger, Severino e la questione della tecnica

La questione della tecnica in un raffronto tra la prospettiva severiniana e quella heideggeriana

Mitochondrial ferritin deficiency reduces male fertility in mice

Mitochondrial ferritin (FtMt) is a functional ferritin targeted to mitochondria that is highly expressed in thetestis. To investigate the role of FtMt in the testis we set up a series of controlled matings between FtMt gene-deletion mice(FtMt/) with FtMtþ/þ mice. We found that the number of newborns per litter and the fertility rate were strongly reducedfor the FtMt/ males, but not for the females, indicating that FtMt has an important role for male fertility. Themorphology of the testis and ...

Ferritin is secreted via 2 distinct nonclassical vesicular pathways

Ferritin turnover plays a major role in tissue iron homeostasis, and ferritin malfunction is associated with impaired iron homeostasis and neurodegenerative diseases. In most eukaryotes, ferritin is considered an intracellular protein that stores iron in a nontoxic and bioavailable form. In insects, ferritin is a classically secreted protein and plays a major role in systemic iron distribution. Mammalian ferritin lacks the signal peptide for classical endoplasmic reticulum–Golgi secretion but...

MICE LACKING MITOCHONDRIAL FERRITIN ARE MORE SENSITIVE TO DOXORUBICIN-MEDIATED CARDIOTOXICITY

Mitochondrial ferritin is a functional ferritin that localizes in the mitochondria. It is expressed in the testis, heart, brain, and cells with active respiratory activity. Its overexpression in cultured cells protected against oxidative damage and reduced cytosolic iron availability. However, no overt phenotype was described inmice with inactivation of the FtMt gene. Here, we used the doxorubicin model of cardiac injury in a novel strain of FtMt-null mice to investigate the antioxidant role ...

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