1 Contributo su Rivista

1 Contributo su Rivista: [46327] Home page macrotipologia

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1.1 Articolo in rivista 38980
1.1.1 Articolo in rivista - Review 1574
1.1.2. Articolo in Rivista - Letter, Note 838
1.1.3. Articolo in Rivista - Editorial, Comment, Reply 1136
1.1.4. Guidelines, Consensus 111
1.1.5. Erratum 187
1.2 Recensione in rivista 283
1.3 Scheda bibliografica 14
1.4 Nota a sentenza 0
1.5 Abstract in rivista 3192
1.6 Traduzione in rivista 12

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Sleep changes during a spontaneous manic episode: PSG assessment in a clinical context

Sleep plays a key role in the pathogenesis and clinical presentation of mood disorders. However, only a few studies have investigated sleep architecture during the manic episodes of Bipolar Disorder (BD) and changes in sleep parameters that follow clinical variations. Twenty-one patients (8 males, 13 females) affected by BD, manic phase, underwent polysomnographic recordings (PSG) at the beginning of the admission in our ward (T0) and after three weeks of hospital treatment (T1). All particip...

Recommendations on the use of gadolinium-based contrast agents in the diagnosis and monitoring of common adult intracranial tumours

Gadolinium-based contrast agents (GBCAs) have been indispensable in intracranial tumour imaging, particularly for detecting and characterising malignant lesions, as well as assessing treatment response and disease progression. However, growing concerns about gadolinium deposition in the central nervous system and its environmental impact have prompted a re-evaluation of its use, particularly in the management of benign or stable lesions. This review examines the role of GBCAs in imaging the m...

Endoscopic Ultrasound (EUS)-Based Multimodal Diagnosis of a Rare Intramural Esophageal Squamous Cell Carcinoma: Case Report and Literature Review

Esophageal squamous cell carcinoma (ESCC) is the most prevalent histological subtype of esophageal cancer worldwide, typically manifesting as an endoluminal mass with overt mucosal involvement. Exceptionally, however, ESCC may present with an intramural growth pattern beneath an apparently intact mucosal surface, a presentation that is exceedingly rare and prone to misdiagnosis. In such cases, repeated endoscopic biopsies are frequently non-diagnostic, thereby delaying appropriate management....

Patient-reported outcomes in the SERENA-6 trial of camizestrant plus CDK4/6 inhibitor in patients with advanced breast cancer and emergent ESR1 mutations during first-line endocrine-based therapy

Background: In SERENA-6, switching from aromatase inhibitor (AI) to camizestrant with continuation of CDK4/6 inhibitor (CDK4/6i) guided by emergence of ESR1 mutations (ESR1-mut) during first-line AI-CDK4/6i in patients with hormone receptor (HR)-positive advanced breast cancer (ABC) resulted in statistically significant and clinically meaningful improvement in progression-free survival compared with AI-CDK4/6i and reduction in the risk of deterioration in global health status (GHS)/quality of...

Nerve pathology is prevented by linker proteins in mouse models for LAMA2-related muscular dystrophy

LAMA2-related muscular dystrophy (LAMA2 MD or MDC1A) is a devastating congenital muscular dystrophy that is caused by mutations in the LAMA2 gene encoding laminin-α2, the long chain of several heterotrimeric laminins. Laminins are essential components of the extracellular matrix that interface with underlying cells. The pathology of LAMA2 MD patients is dominated by an early-onset, severe muscular dystrophy that ultimately leads to death by respiratory insufficiency. However, pathology in non...

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