Multimodal imaging in Schubert-Bornschein congenital stationary night blindness

Background Schubert-Bornschein (SB) is the most common type of people with congenital stationary night blindness (CSNB). The aim of the study is to describe the optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA) findings in patients with SB CSNB. Methods Prospective, observational case series including three patients with genetically confirmed CSNB along with matched controls, who underwent complete ophthalmic examination and multimodal imaging. Results On ...

New insights in the multimodal imaging of retinitis pigmentosa

Retinitis pigmentosa (RP) is a group of inherited rod-cone dystrophies, noted for a high genotypical and phenotypical heterogeneity. Traditionally, VA, visual field, and electroretinography have been used to assess RP progression. However, visual acuity and visual field tests are essentially subjective and, especially in the late stages of the disease, are unable to confidently reveal minor progression. Therefore, there is a need for novel examination modalities that rely on quantitative, str...

Confocal MultiColor Signal Depends on Perfusion Characteristics of Retinal Microaneurysms in Diabetic Retinopathy as Detected by OCTA

Purpose: To propose a noninvasive way of classifying multimodal imaging of retinal microaneurysms (MA) secondary to diabetic retinopathy (DR). Methods: The research was designed as a cross-sectional, observational study of patients affected by DR. Multimodal imaging included confocal MultiColor imaging, optical coherence tomography (OCT) and OCT angiography (OCTA). MA green-and infrared-reflectance components were assessed by confocal MultiColor imaging, reflec-tivity properties by OCT, and M...

Conjunctival vessel density analysis as a marker of inflammation in dry eye disease