1 Contributo su Rivista

1 Contributo su Rivista: [46813] Home page macrotipologia

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1.1 Articolo in rivista 39326
1.1.1 Articolo in rivista - Review 1673
1.1.2. Articolo in Rivista - Letter, Note 862
1.1.3. Articolo in Rivista - Editorial, Comment, Reply 1152
1.1.4. Guidelines, Consensus 111
1.1.5. Erratum 194
1.2 Recensione in rivista 284
1.3 Scheda bibliografica 14
1.4 Nota a sentenza 0
1.5 Abstract in rivista 3185
1.6 Traduzione in rivista 12

Prodotti recenti

A screening operative model for detecting subjects with idiopathic REM sleep behavior disorder: the SOMIRBD study

Multimodal MRI neurodevelopmental profiling in type 1 diabetes: long-term effects of MDI vs CSII treatments

Context The developing brain is particularly vulnerable to glycemic extremes in early-onset type 1 diabetes (T1D). However, how treatment-specific modalities may influence long-term neurodevelopmental trajectories remains poorly understood. Objective To characterize multimodal MRI neurodevelopmental profiles in pediatric T1D and evaluate treatment-related effects of multiple daily injections (MDI) vs continuous subcutaneous insulin infusion (CSII) on brain structure, function, and test whethe...

MYC modulates TOP2A diffusion to promote substrate detection and activity

Topoisomerases alleviate DNA supercoiling by cleaving and resealing DNA strands. Previously, we showed that the oncoprotein MYC recruits and stimulates topoisomerases to remove DNA entanglements generated by oncogenic transcription. Understanding this mechanism may suggest methods to inhibit MYC-driven topoisomerase activation, targeting tumor-specific transcription. Here, we demonstrate that the essential topoisomerase TOP2A in human cells exists in a dynamic equilibrium between sequestratio...

Real-world insights into coronary CTA prognostication: value of semiquantitative scores

Purpose Several semiquantitative coronary computed tomography angiography (CCTA) scores including different parameters describing stenosis degree, plaque burden and plaque features have been developed for diagnostic and prognostic purposes. However, their clinical application is still limited. The aim of the study is to assess the prognostic implication of semiquantitative coronary CCTA scores in clinical practice. Material and methods In this retrospective, single-center study, 6818 adults w...

Liquid–liquid phase separation in neural development

Liquid–liquid phase separation (LLPS) is a physicochemical process in which a homogeneous mixture of molecules separates into a denser phase originating from preferential self-assembly, driven by multivalent interactions, frequently mediated by intrinsically disordered protein regions, RNAs, or structured modular domains. LLPS produces a large variety of nuclear or cytoplasmic membrane-less biomolecular condensates with liquid-like properties. The importance of LLPS in several aspects of neur...

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