This chapter explores the mechanisms that regulate Purkinje cell neuro- genesis, revealing the finely timed contribution of many regulatory genes in the control of PC progenitor specification, proliferation, subtype differentiation, migra- tion, and survival from the cerebellar primordium to the end of prenatal embryogen- esis, discussing some of the key molecules involved and the ways they combine to generate the complex adult cerebellar architecture.
Early Purkinje cell development and the origin of cerebellar patterning.
Casoni, Filippo;Cremona, OttavioPenultimo
;Consalez, Gian Giacomo
2017-01-01
Abstract
This chapter explores the mechanisms that regulate Purkinje cell neuro- genesis, revealing the finely timed contribution of many regulatory genes in the control of PC progenitor specification, proliferation, subtype differentiation, migra- tion, and survival from the cerebellar primordium to the end of prenatal embryogen- esis, discussing some of the key molecules involved and the ways they combine to generate the complex adult cerebellar architecture.File in questo prodotto:
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