The aim of the study was to characterise the humoral response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients with diabetes. Demonstrating the ability to mount an appropriate antibody response in the presence of hyperglycaemia is relevant for the comprehension of mechanisms related to the observed worse clinical outcome of coronavirus disease 2019 (COVID-19) pneumonia in patients with diabetes and for the development of any future vaccination campaign to prevent SARS-CoV-2 infection.

Antibody response to multiple antigens of SARS-CoV-2 in patients with diabetes: an observational cohort study / Lampasona, Vito; Secchi, Massimiliano; Scavini, Marina; Bazzigaluppi, Elena; Brigatti, Cristina; Marzinotto, Ilaria; Davalli, Alberto; Caretto, Amelia; Laurenzi, Andrea; Martinenghi, Sabina; Molinari, Chiara; Vitali, Giordano; Di Filippo, Luigi; Mercalli, Alessia; Melzi, Raffaella; Tresoldi, Cristina; Rovere-Querini, Patrizia; Landoni, Giovanni; Ciceri, Fabio; Bosi, Emanuele; Piemonti, Lorenzo. - In: DIABETOLOGIA. - ISSN 0012-186X. - 63:12(2020), pp. 2548-2558. [10.1007/s00125-020-05284-4]

Antibody response to multiple antigens of SARS-CoV-2 in patients with diabetes: an observational cohort study

Marzinotto, Ilaria;Di Filippo, Luigi;Rovere-Querini, Patrizia;Landoni, Giovanni;Ciceri, Fabio;Bosi, Emanuele
Penultimo
;
Piemonti, Lorenzo
Ultimo
2020-01-01

Abstract

The aim of the study was to characterise the humoral response against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in patients with diabetes. Demonstrating the ability to mount an appropriate antibody response in the presence of hyperglycaemia is relevant for the comprehension of mechanisms related to the observed worse clinical outcome of coronavirus disease 2019 (COVID-19) pneumonia in patients with diabetes and for the development of any future vaccination campaign to prevent SARS-CoV-2 infection.
2020
Antibodies
COVID-19
Diabetes
Human
Humoral response
Receptor-binding domain
SARS-CoV-2
Survival rate
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/104852
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