Type 1 diabetes (T1D) is characterised by islet autoimmunity and beta cell destruction. A gut microbiota-immunological interplay is involved in the pathophysiology of T1D. We studied microbiota-mediated effects on disease progression in patients with type 1 diabetes using faecal microbiota transplantation (FMT).

Faecal microbiota transplantation halts progression of human new-onset type 1 diabetes in a randomised controlled trial / de Groot, P., Nicolic, T., Pellegrini, S., Sordi, V., Imangaliyev, S., Rampanelli, E., Hanssen, N., Attaye, I., Bakker, G., Duinkerken, G., Joosten, A., Prodan, A., Levin, E., Levels, H., Potter van Loon, B., van Bon, A., Brouwer, C., van Dam, S., Simsek, S., van Raalte, D., et al.. - In: GUT. - ISSN 0017-5749. - 70:1(2021), pp. 92-105. [Epub ahead of print] [10.1136/gutjnl-2020-322630]

Faecal microbiota transplantation halts progression of human new-onset type 1 diabetes in a randomised controlled trial

Piemonti, Lorenzo;
2021-01-01

Abstract

Type 1 diabetes (T1D) is characterised by islet autoimmunity and beta cell destruction. A gut microbiota-immunological interplay is involved in the pathophysiology of T1D. We studied microbiota-mediated effects on disease progression in patients with type 1 diabetes using faecal microbiota transplantation (FMT).
2021
diabetes mellitus
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/106087
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