We assessed the effect of stage, grade, and histologic type on cancer-specific mortality after surgery in candidates for 1 of the 4 North American ongoing immune-oncology checkpoint inhibitor trials. Important differences exist in the inclusion criteria among the 4 ongoing adjuvant trials. By generating 4 random samples, we have demonstrated that the differences in the inclusion criteria are reflected in the differences in the mortality rates.

A Plea for Optimizing Selection in Current Adjuvant Immunotherapy Trials for High-risk Nonmetastatic Renal Cell Carcinoma According to Expected Cancer-specific Mortality

Mazzone E.;Briganti A.;
2020-01-01

Abstract

We assessed the effect of stage, grade, and histologic type on cancer-specific mortality after surgery in candidates for 1 of the 4 North American ongoing immune-oncology checkpoint inhibitor trials. Important differences exist in the inclusion criteria among the 4 ongoing adjuvant trials. By generating 4 random samples, we have demonstrated that the differences in the inclusion criteria are reflected in the differences in the mortality rates.
2020
Inglese
Elsevier Inc.
18
4
314
321.e1
Epub ahead of print
Adjuvant therapy
Clear cell
Immune checkpoint inhibitors
Nephrectomy
Sarcomatoid
none
13
info:eu-repo/semantics/article
262
Palumbo, C.; Mazzone, E.; Mistretta, F. A.; Knipper, S.; Perrotte, P.; Shariat, S. F.; Saad, F.; Kapoor, A.; Lattouf, J. -B.; Simeone, C.; Briganti, A...espandi
1 Contributo su Rivista::1.1 Articolo in rivista
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/108547
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