In patients with a positron emission tomography (PET) scan suggestive of unilateral nodal recurrence from prostate cancer (PCa) after radical prostatectomy, a bilateral salvage lymph node dissection demonstrated a contralateral disease missed by imaging in approximately one of five patients. This rate varied according to the number of positive spots and PET tracer, with the lowest rate of missed PCa in men diagnosed with a single positive spot at 68Ga prostate-specific membrane antigen PET scan (6%). If replicated, our data suggest that these patients might be considered for unilateral extended pelvic salvage lymph node dissection when correct staging is considered as an endpoint.

Assessing the Best Surgical Template at Salvage Pelvic Lymph Node Dissection for Nodal Recurrence of Prostate Cancer After Radical Prostatectomy: When Can Bilateral Dissection be Omitted? Results from a Multi-institutional Series

Bravi C. A.;Gandaglia G.;Mazzone E.;Montorsi F.;Briganti A.
2020-01-01

Abstract

In patients with a positron emission tomography (PET) scan suggestive of unilateral nodal recurrence from prostate cancer (PCa) after radical prostatectomy, a bilateral salvage lymph node dissection demonstrated a contralateral disease missed by imaging in approximately one of five patients. This rate varied according to the number of positive spots and PET tracer, with the lowest rate of missed PCa in men diagnosed with a single positive spot at 68Ga prostate-specific membrane antigen PET scan (6%). If replicated, our data suggest that these patients might be considered for unilateral extended pelvic salvage lymph node dissection when correct staging is considered as an endpoint.
2020
11
C-choline positron emission tomography scan
68
Ga prostate-specific membrane antigen positron emission tomography scan
Metastasis-directed therapy
Neoplasm recurrence
Prostate cancer
Salvage lymph node dissection
Surgical template
Unilateral dissection
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/108553
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