Since its introduction to the diagnostic pathway for prostate cancer management, prostate-specific membrane antigen (PSMA)–ligand PET has demonstrated great potential. PSMA-ligand imaging is increasingly influencing therapeutic decision making, although its impact on patient outcomes still needs to be defined. One relatively new application, enabled through chemical and engineering efforts, is PSMA-guided surgery. This review highlights the potential of PSMA-guided surgery and discusses its implications in lymph node dissection in primary and recurrent prostate cancer.

Prostate-specific membrane antigen – Guided surgery

Briganti A.;
2020-01-01

Abstract

Since its introduction to the diagnostic pathway for prostate cancer management, prostate-specific membrane antigen (PSMA)–ligand PET has demonstrated great potential. PSMA-ligand imaging is increasingly influencing therapeutic decision making, although its impact on patient outcomes still needs to be defined. One relatively new application, enabled through chemical and engineering efforts, is PSMA-guided surgery. This review highlights the potential of PSMA-guided surgery and discusses its implications in lymph node dissection in primary and recurrent prostate cancer.
2020
Fluorescence
Image-guided surgery
Lymph node dissection
Prostate cancer
Salvage
Humans
Ligands
Lymph Node Excision
Lymphatic Metastasis
Male
Medical Oncology
Neoplasm Recurrence, Local
Positron-Emission Tomography
Prostatic Neoplasms
Proteasome Endopeptidase Complex
Radiopharmaceuticals
Radiosurgery
Salvage Therapy
Surgery, Computer-Assisted
Technetium
Urology
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/108627
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