Liquid-liquid phase separation drives the formation of biomolecular condensates (BCs) for the spatiotemporal organization of several cellular processes. Recent evidences indicate that components of plasma-membrane-associated platforms form biomolecular condensates near focal adhesions (FAs), and suggest that phase separation regulates dynamic processes occurring at the front of migrating cells.

Biomolecular Condensates at the Front: Cell Migration Meets Phase Separation

de Curtis, Ivan
2021-01-01

Abstract

Liquid-liquid phase separation drives the formation of biomolecular condensates (BCs) for the spatiotemporal organization of several cellular processes. Recent evidences indicate that components of plasma-membrane-associated platforms form biomolecular condensates near focal adhesions (FAs), and suggest that phase separation regulates dynamic processes occurring at the front of migrating cells.
2021
biomolecular condensates
cell migration
focal adhesions
liquid–liquid phase separation
plasma-membrane-associated platforms
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/109727
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