Dermatofibromas are common benign fibrohistiocytic tumors that are most often solitary. The occurrence of multiple eruptive dermatofibromas (MEDF), on the contrary, is a rare event. MEDF have been reported in the setting of autoimmune diseases, treated with immunosuppressive drugs, in the course of HIV infection and in neoplastic diseases. An association with immunosuppression has led to the speculation that they are the result of an abortive immunoreactive process. Here, we describe a patient with Sézary syndrome and a patient with multiple IgA myeloma who developed MEDF. These associations have not been reported previously. © Journal compilation © 2008 International Society of Dermatology.
Multiple eruptive dermatofibromas and immunosuppression: report of two cases and review of the literature / Zaccaria, E.; Rebora, A.; Rongioletti, F.. - In: INTERNATIONAL JOURNAL OF DERMATOLOGY. - ISSN 0011-9059. - 47:7(2008), pp. 723-727. [10.1111/j.1365-4632.2008.03575.x]
Multiple eruptive dermatofibromas and immunosuppression: report of two cases and review of the literature
Rongioletti, F.
2008-01-01
Abstract
Dermatofibromas are common benign fibrohistiocytic tumors that are most often solitary. The occurrence of multiple eruptive dermatofibromas (MEDF), on the contrary, is a rare event. MEDF have been reported in the setting of autoimmune diseases, treated with immunosuppressive drugs, in the course of HIV infection and in neoplastic diseases. An association with immunosuppression has led to the speculation that they are the result of an abortive immunoreactive process. Here, we describe a patient with Sézary syndrome and a patient with multiple IgA myeloma who developed MEDF. These associations have not been reported previously. © Journal compilation © 2008 International Society of Dermatology.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.