The potential virucidal effects of UV-C irradiation on SARS-CoV-2 were experimentally evaluated for different illumination doses and virus concentrations (1000, 5, 0.05 MOI). At a virus density comparable to that observed in SARS-CoV-2 infection, an UV-C dose of just 3.7 mJ/cm2 was sufficient to achieve a more than 3-log inactivation without any sign of viral replication. Moreover, a complete inactivation at all viral concentrations was observed with 16.9 mJ/cm2. These results could explain the epidemiological trends of COVID-19 and are important for the development of novel sterilizing methods to contain SARS-CoV-2 infection.
UV-C irradiation is highly effective in inactivating SARS-CoV-2 replication / Biasin, M., Bianco, A., Pareschi, G., Cavalleri, A., Cavatorta, C., Fenizia, C., Galli, P., Lessio, L., Lualdi, M., Tombetti, E., Ambrosi, A., Redaelli, E.M.A., Saulle, I., Trabattoni, D., Zanutta, A., Clerici, M.. - In: SCIENTIFIC REPORTS. - ISSN 2045-2322. - 11:1(2021), p. 6260. [10.1038/s41598-021-85425-w]
UV-C irradiation is highly effective in inactivating SARS-CoV-2 replication
Ambrosi, Alessandro;
2021-01-01
Abstract
The potential virucidal effects of UV-C irradiation on SARS-CoV-2 were experimentally evaluated for different illumination doses and virus concentrations (1000, 5, 0.05 MOI). At a virus density comparable to that observed in SARS-CoV-2 infection, an UV-C dose of just 3.7 mJ/cm2 was sufficient to achieve a more than 3-log inactivation without any sign of viral replication. Moreover, a complete inactivation at all viral concentrations was observed with 16.9 mJ/cm2. These results could explain the epidemiological trends of COVID-19 and are important for the development of novel sterilizing methods to contain SARS-CoV-2 infection.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
