The purpose of this study was to evaluate the impact of surgical timing on survival in patients with left-sided infective endocarditis (IE). This was a retrospective study including 313 patients with left-sided IE between 2009 and 2017. Surgery was defined as urgent (US) or early (ES) if performed within 7 or 28 days, respectively. A multivariable Cox regression analysis including US and ES as time-dependent variables was performed to assess the impact on 1-year mortality. ES was associated with a better survival (aHR 0.349, 95% CI 0.135–0.902), as US (aHR 0.262, 95% CI 0.075–0.915). ES and US were associated with a better prognosis in patients with left-sided IE.
Impact of surgical timing on survival in patients with infective endocarditis: a time-dependent analysis / Ripa, M.; Chiappetta, S.; Castiglioni, B.; Agricola, E.; Busnardo, E.; Carletti, S.; Castiglioni, A.; De Bonis, M.; La Canna, G.; Oltolini, C.; Pajoro, U.; Pasciuta, R.; Tassan Din, C.; Scarpellini, P.. - In: EUROPEAN JOURNAL OF CLINICAL MICROBIOLOGY & INFECTIOUS DISEASES. - ISSN 0934-9723. - 40:6(2021), pp. 1319-1324. [10.1007/s10096-020-04133-x]
Impact of surgical timing on survival in patients with infective endocarditis: a time-dependent analysis
Ripa M.;Agricola E.;Castiglioni A.;De Bonis M.;
2021-01-01
Abstract
The purpose of this study was to evaluate the impact of surgical timing on survival in patients with left-sided infective endocarditis (IE). This was a retrospective study including 313 patients with left-sided IE between 2009 and 2017. Surgery was defined as urgent (US) or early (ES) if performed within 7 or 28 days, respectively. A multivariable Cox regression analysis including US and ES as time-dependent variables was performed to assess the impact on 1-year mortality. ES was associated with a better survival (aHR 0.349, 95% CI 0.135–0.902), as US (aHR 0.262, 95% CI 0.075–0.915). ES and US were associated with a better prognosis in patients with left-sided IE.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
