Mitochondria and their dynamics fuel most cellular processes both in physiological and pathological conditions. In the central nervous system, mitochondria sustain synaptic transmission and plasticity via multiple mechanisms which include their redistribution and/or expansion to higher energy demanding sites, sustaining activity changes and promoting morphological circuit adaptations.

A novel integrated approach to estimate the mitochondrial content of neuronal cells and brain tissues / Spadini, Sara; Racchetti, Gabriella; Adiletta, Alice; Lamanna, Jacopo; Moro, Andrea Stefano; Ferro, Mattia; Zimarino, Vincenzo; Malgaroli, Antonio. - In: JOURNAL OF NEUROSCIENCE METHODS. - ISSN 0165-0270. - 363:(2021), p. 109351. [10.1016/j.jneumeth.2021.109351]

A novel integrated approach to estimate the mitochondrial content of neuronal cells and brain tissues

Lamanna, Jacopo;Malgaroli, Antonio
2021-01-01

Abstract

Mitochondria and their dynamics fuel most cellular processes both in physiological and pathological conditions. In the central nervous system, mitochondria sustain synaptic transmission and plasticity via multiple mechanisms which include their redistribution and/or expansion to higher energy demanding sites, sustaining activity changes and promoting morphological circuit adaptations.
2021
Energy metabolism
LTP
Mitochondria
Neuronal metabolism
Synaptic plasticity
Synaptic transmission
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/118793
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