A recent study in a mouse model of colitis has demonstrated that interleukin (IL)-13, through inhibition of the mixed type 1 and type 17 T-helper cell inflammatory response, has a protective effect. the decoy receptor Il-13R alpha 2 inhibits this protective effect, suggesting blockade of IL-13R alpha 2 as a potential therapy for patients with IBD.
IBD Of mice and men-shedding new light on IL-13 activity in IBD / Danese, S. - In: NATURE REVIEWS. GASTROENTEROLOGY & HEPATOLOGY. - ISSN 1759-5045. - 8:3(2011), pp. 128-+. [10.1038/nrgastro.2011.17]
IBD Of mice and men-shedding new light on IL-13 activity in IBD
Danese S
2011-01-01
Abstract
A recent study in a mouse model of colitis has demonstrated that interleukin (IL)-13, through inhibition of the mixed type 1 and type 17 T-helper cell inflammatory response, has a protective effect. the decoy receptor Il-13R alpha 2 inhibits this protective effect, suggesting blockade of IL-13R alpha 2 as a potential therapy for patients with IBD.File in questo prodotto:
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