Janus kinases inhibitors (JAKi) are new small molecules recently introduced in the armamentarium of treatments for Inflammatory Bowel Disease (IBD). Janus Kinases (JAK) are tyrosine kinases that act by linkage with different intracellular receptors, regulating cytokines gene transcription implicated in the inflammatory burden seen in IBD patients.
JAK selectivity: more precision less troubles / Roda, Giulia; Dal Buono, Arianna; Argollo, Marjorie; Danese, Silvio. - In: EXPERT REVIEW OF GASTROENTEROLOGY & HEPATOLOGY. - ISSN 1747-4124. - 14:9(2020), pp. 789-796-796. [10.1080/17474124.2020.1780120]
JAK selectivity: more precision less troubles
Danese, Silvio
2020-01-01
Abstract
Janus kinases inhibitors (JAKi) are new small molecules recently introduced in the armamentarium of treatments for Inflammatory Bowel Disease (IBD). Janus Kinases (JAK) are tyrosine kinases that act by linkage with different intracellular receptors, regulating cytokines gene transcription implicated in the inflammatory burden seen in IBD patients.File in questo prodotto:
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