The authors report a case of a male patient affected by macular hole. In particular, a hyperreflective tissue was found on optical coherence tomography (OCT) examination in macular region, just above the retinal pigment epithelium (RPE). OCT angiography (OCTA) did not show the presence of vascular tissue, thus the hyperreflective material was ascribed to primary gliotic tissue. This case highlights the ability for Muller cells placed near macular holes to migrate up to the RPE and to produce gliotic tissue.

Gliotic tissue simulating a macular neovascularization in full-thickness macular hole

Vigano', Chiara;Borrelli, Enrico;Sacconi, Riccardo;Brambati, Maria;Bandello, Francesco;Querques, Giuseppe
2022-01-01

Abstract

The authors report a case of a male patient affected by macular hole. In particular, a hyperreflective tissue was found on optical coherence tomography (OCT) examination in macular region, just above the retinal pigment epithelium (RPE). OCT angiography (OCTA) did not show the presence of vascular tissue, thus the hyperreflective material was ascribed to primary gliotic tissue. This case highlights the ability for Muller cells placed near macular holes to migrate up to the RPE and to produce gliotic tissue.
2022
Retinal pathology/research
agerelated macular degeneration
macular hole
pediatric ophthalmology
retina
retinal cell biology
vitreous/retinal disease
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/120113
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