IDH1-mutated intrahepatic cholangiocarcinomas (IDH1m iCCAs) could be treated with anti-IDH1 drugs, although the high heterogeneity in this class of tumours could limit treatment efficacy.

Next-generation sequencing analysis of cholangiocarcinoma identifies distinct IDH1-mutated clusters

De Cobelli, Francesco;Aldrighetti, Luca;Cascinu, Stefano;Casadei-Gardini, Andrea
2022

Abstract

IDH1-mutated intrahepatic cholangiocarcinomas (IDH1m iCCAs) could be treated with anti-IDH1 drugs, although the high heterogeneity in this class of tumours could limit treatment efficacy.
Cholangiocarcinoma
Clustering analysis
Genomic profiling
IDH1 mutation
Next-generation sequencing
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/132333
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