Biliary tract cancers are rare malignancies with a poor prognosis and scarce therapeutic strategies. The significance of BRCAness in this setting is already unknown.

Gene mutational profile of BRCAness and clinical implication in predicting response to platinum-based chemotherapy in patients with intrahepatic cholangiocarcinoma

De Cobelli, Francesco;Aldrighetti, Luca;Cascinu, Stefano;Casadei-Gardini, Andrea
2022

Abstract

Biliary tract cancers are rare malignancies with a poor prognosis and scarce therapeutic strategies. The significance of BRCAness in this setting is already unknown.
BRCAness phenotype
Biliary tract cancer
PARP inhibitors
Platinum-based chemotherapy
Antineoplastic Agents
Bile Ducts, Intrahepatic
Humans
Mutation
Prognosis
Bile Duct Neoplasms
Cholangiocarcinoma
Genetic Profile
Organoplatinum Compounds
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/132357
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