Autoimmune diseases are often associated with human leukocyte antigen (HLA) haplotypes, indicating that changes in major histocompatibility complex (MHC)-dependent self-peptide or antigen presentation contribute to autoimmunity. In our study, we aimed to investigate HLA alleles in a large European cohort of autoimmune pancreatitis (AIP) patients.

HLA-DRB1∗16 and -DQB1∗05 alleles are strongly associated with autoimmune pancreatitis in a cohort of hundred patients / Goni, Elisabetta; Regel, Ivonne; Mahajan, Ujjwal Mukund; Amodio, Antonio; De Marchi, Giulia; Beyer, Georg; Zuppardo, Raffaella Alessia; Di Leo, Milena; Lanzillotta, Marco; Bonatti, Francesco; Kauke, Teresa; Dick, Andrea; Weiss, Frank Ulrich; Schönermarck, Ulf; Lerch, Markus M; Frulloni, Luca; Cavestro, Giulia Martina; Mayerle, Julia. - In: PANCREATOLOGY. - ISSN 1424-3903. - 22:4(2022), pp. 466-471. [10.1016/j.pan.2022.03.015]

HLA-DRB1∗16 and -DQB1∗05 alleles are strongly associated with autoimmune pancreatitis in a cohort of hundred patients

Lanzillotta, Marco;Cavestro, Giulia Martina;
2022-01-01

Abstract

Autoimmune diseases are often associated with human leukocyte antigen (HLA) haplotypes, indicating that changes in major histocompatibility complex (MHC)-dependent self-peptide or antigen presentation contribute to autoimmunity. In our study, we aimed to investigate HLA alleles in a large European cohort of autoimmune pancreatitis (AIP) patients.
2022
AIP subtypes
Autoimmune pancreatitis
Caucasian population
HLA class II genes
HLA typing
Alleles
Gene Frequency
Genetic Predisposition to Disease
HLA-DRB1 Chains
HLA-DRB4 Chains
Haplotypes
Humans
Autoimmune Pancreatitis
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/133294
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