D-2-hydroxyglutarate (2HG) characterizes IDH-mutant gliomas and can be detected and quantified with edited MRS (MEGA-PRESS). Here, we investigated the clinical, radiological, and molecular parameters affecting 2HG levels.

In vivo 2-Hydroxyglutarate Monitoring With Edited MR Spectroscopy for the Follow-up of IDH-Mutant Diffuse Gliomas: The IDASPE Prospective Study

Berzero, Giulia;
2022-01-01

Abstract

D-2-hydroxyglutarate (2HG) characterizes IDH-mutant gliomas and can be detected and quantified with edited MRS (MEGA-PRESS). Here, we investigated the clinical, radiological, and molecular parameters affecting 2HG levels.
2022
2-hydroxyglutarate (2HG)
IDH1/2 mutations
diffuse gliomas
edited MR spectroscopy
noninvasive detection
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/133911
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