D-2-hydroxyglutarate (2HG) characterizes IDH-mutant gliomas and can be detected and quantified with edited MRS (MEGA-PRESS). Here, we investigated the clinical, radiological, and molecular parameters affecting 2HG levels.

In vivo 2-Hydroxyglutarate Monitoring With Edited MR Spectroscopy for the Follow-up of IDH-Mutant Diffuse Gliomas: The IDASPE Prospective Study / Di Stefano, A.L., Nichelli, L., Berzero, G., Valabregue, R., Touat, M., Capelle, L., Pontoizeau, C., Bielle, F., Lerond, J., Giry, M., Villa, C., Baussart, B., Dehais, C., Galanaud, D., Baldini, C., Savatovsky, J., Dhermain, F., Deelchand, D.K., Ottolenghi, C., Lehericy, S., et al.. - In: NEUROLOGY. - ISSN 0028-3878. - 100:1(2023), pp. E94-E106. [Epub ahead of print] [10.1212/WNL.0000000000201137]

In vivo 2-Hydroxyglutarate Monitoring With Edited MR Spectroscopy for the Follow-up of IDH-Mutant Diffuse Gliomas: The IDASPE Prospective Study

Berzero, Giulia;
2023-01-01

Abstract

D-2-hydroxyglutarate (2HG) characterizes IDH-mutant gliomas and can be detected and quantified with edited MRS (MEGA-PRESS). Here, we investigated the clinical, radiological, and molecular parameters affecting 2HG levels.
2023
2-hydroxyglutarate (2HG)
IDH1/2 mutations
diffuse gliomas
edited MR spectroscopy
noninvasive detection
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/133911
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