Routine Molecular Profiling in Both Resectable and Unresectable Pancreatic Adenocarcinoma: Relevance of Cytologic Samples

Redegalli, Miriam; Grassini, Greta; Magliacane, Gilda; Pecciarini, Lorenza; Schiavo Lena, Marco; Smart, Chanel E; Johnston, Rebecca L; Waddell, Nicola; Maestro, Roberta; Macchini, Marina; Orsi, Giulia; Petrone, Maria Chiara; Rossi, Gemma; Balzano, Gianpaolo; Falconi, Massimo; Arcidiacono, Paolo G; Reni, Michele; Doglioni, Claudio; Cangi, Maria Giulia

doi:10.1016/j.cgh.2022.10.014

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive disease, for which it is crucial to promptly detect actionable and prognostic alterations to drive specific therapeutic decisions, regardless of tumor resectability status. Endoscopic ultrasonography-guided fine-needle aspiration (EUS-FNA) is of key importance for PDAC diagnosis and can contribute significantly to tumor molecular profiling.

Routine Molecular Profiling in Both Resectable and Unresectable Pancreatic Adenocarcinoma: Relevance of Cytologic Samples / Redegalli, M., Grassini, G., Magliacane, G., Pecciarini, L., Schiavo Lena, M., Smart, C.E., Johnston, R.L., Waddell, N., Maestro, R., Macchini, M., Orsi, G., Petrone, M.C., Rossi, G., Balzano, G., Falconi, M., Arcidiacono, P.G., Reni, M., Doglioni, C., Cangi, M.G.. - In: CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. - ISSN 1542-3565. - 21:11(2023), pp. 2825-2833. [10.1016/j.cgh.2022.10.014]