: Granulosa cell tumors of the ovary have an indolent behavior and a good prognosis, but a high incidence of local recurrence after surgery. The best treatment in the recurrent setting is unclear and randomized clinical trials on the management in the recurrent setting are lacking. The role of radiotherapy is controversial in adjuvant settings and unknown in case of relapse after surgery. This review aims to summarize the level of evidence of the role of radiation treatments for granulosa cell tumors of the ovary.

Granulosa cell tumors (GCTs) of the ovary: What is the role of radiotherapy? / Barcellini, Amelia; Mangili, Giorgia; Fodor, Andrei; Secondino, Simona; Zerbetto, Flavia; Charalampopoulou, Alexandra; Pignata, Sandro; Orlandi, Ester; Bergamini, Alice. - In: CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. - ISSN 1040-8428. - 181:(2023). [10.1016/j.critrevonc.2022.103889]

Granulosa cell tumors (GCTs) of the ovary: What is the role of radiotherapy?

Bergamini, Alice
Ultimo
2023-01-01

Abstract

: Granulosa cell tumors of the ovary have an indolent behavior and a good prognosis, but a high incidence of local recurrence after surgery. The best treatment in the recurrent setting is unclear and randomized clinical trials on the management in the recurrent setting are lacking. The role of radiotherapy is controversial in adjuvant settings and unknown in case of relapse after surgery. This review aims to summarize the level of evidence of the role of radiation treatments for granulosa cell tumors of the ovary.
2023
Granulosa cell tumor
Radiotherapy
Rare tumors
Sex cord-stromal tumor
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/135154
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