Endophthalmitis due to Listeria monocytogenes is a rare form of listeriosis. Here, we report two cases that occurred in patients with different medical history, a 46-years-old woman with no comorbidities and an elderly man with several comorbidities. There was no history of trauma or surgery in either patient suggesting an endogenous origin. Despite antibiotic treatment, both patients showed poor visual acuity outcomes. Subtyping clinical isolates using whole genome sequencing could allow to characterise Listeria monocytogenes strains involved in rare clinical manifestation, such as in unusual anatomical sites, even in immunocompetent patients.

Clinical characterization and whole genome sequence-based typing of two cases of endophthalmitis due to Listeria monocytogenes / Gori, M.; Bianchi, S.; Ciceri, G.; Lai, A.; Tonelli, M.; Clementi, N.; Clementi, M.; Mancini, N.; Fappani, C.; Zehender, G.; Amendola, A.; Pontello, M.; Tanzi, E.. - In: JOURNAL OF PREVENTIVE MEDICINE AND HYGIENE. - ISSN 1121-2233. - 63:1(2022), pp. E139-E141. [10.15167/2421-4248/jpmh2022.63.1.2261]

Clinical characterization and whole genome sequence-based typing of two cases of endophthalmitis due to Listeria monocytogenes

Tonelli M.;Clementi N.;Clementi M.;Mancini N.;
2022-01-01

Abstract

Endophthalmitis due to Listeria monocytogenes is a rare form of listeriosis. Here, we report two cases that occurred in patients with different medical history, a 46-years-old woman with no comorbidities and an elderly man with several comorbidities. There was no history of trauma or surgery in either patient suggesting an endogenous origin. Despite antibiotic treatment, both patients showed poor visual acuity outcomes. Subtyping clinical isolates using whole genome sequencing could allow to characterise Listeria monocytogenes strains involved in rare clinical manifestation, such as in unusual anatomical sites, even in immunocompetent patients.
2022
Endophthalmitis
Listeriosis
Surveillance
Virulence
Whole-genome sequencing
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/137097
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