A global online survey was administered to 69 islet transplantation programs, covering 84 centers and 5 networks. The survey addressed questions on program organization and activity in the 2000-2020 period, including impact on activity of national health care coverage policies. We obtained full data from 55 institutions or networks worldwide and basic activity data from 6 centers. Additional data were obtained from alternative sources. A total of 94 institutions and 5 networks was identified as having performed islet allotransplantation. 4,365 islet allotransplants (2,608 in Europe, 1,475 in North America, 135 in Asia, 119 in Oceania, 28 in South America) were reported in 2,170 patients in the survey period. From 15 centers active at the start of the study period, the number of simultaneously active islet centers peaked at 54, to progressively decrease to 26 having performed islet allotransplants in 2020. Notably, only 16 centers/networks have done >100 islet allotransplants in the survey period. Types of transplants performed differed notably between North America and the rest of the world, in particular with respect to the near-absence of simultaneous islet-kidney transplantation. Absence of heath care coverage has significantly hampered transplant activity in the past years and the COVID-19 pandemic in 2020.

A Worldwide Survey of Activities and Practices in Clinical Islet of Langerhans Transplantation / R Aghayan, Hamid; Alejandro, Rodolfo; Anazawa, Takayuki; Andres, Axel; Armanet, Mathieu; Badet, Lionel; N Balamurugan, Appakalai; B Barton, Franca; D Bellin, Melena; Y Benhamou, Pierre; Berishvili, Ekaterine; Berney, Thierry; Bertuzzi, Federico; Borot, Sophie; Bosco, Domenico; Bottino, Rita; D Brendel, Mathias; Buron, Fanny; Armando Caicedo, Luis; Casey, John; Cattan, Pierre; Choudhary, Pratik; T Coates, Patrick; Conget, Ignacio; Cooper, Matthew; Jp de Koning, Eelco; Dębska-Ślizień, Alicja; S Desai, Chirag; Dominguez-Gil, Beatriz; Drago, Julian; J Echeverri, Gabriel; Fedaruk, Dzmitry; Gołębiewska, Justyna; A Goss, John; J Hering, Bernhard; H Hyon, Sung; Rv Johnson, Paul; S Jung, Hye; A Kanak, Mazhar; Kandeel, Fouad; Kay, Thomas; Kenmochi, Takashi; Kessler, Laurence; Keymeulen, Bart; Khambalia, Hussein; M Khan, Khalid; H Kim, Jae; Korsgren, Olle; C Kudva, Yogish; Lablanche, Sandrine; Labriola, Leticia; Y Lee, Eun; Lehmann, Roger; Ludwig, Barbara; Lundren, Törbjörn; Luo, Xunrong; Maffi, PAOLA ANGELA MARIA; Markmann, James; Mattina, Alessandro; Meloche, Mark; L Mokshagundam, Sri Prakash; Morgan, Katherine; Munch, Marion; Naziruddin, Bashoo; S Odorico, Jon; Onaca, Nicholas; Paraskevas, Steven; Pattou, François; Pernin, Nadine; Piemonti, Lorenzo; R Rickels, Michael; Ricordi, Camillo; Muñoz Romo, Raul; Saudek, Frantisek; Scholz, Hanne; Am Shapiro, James; Shaw, James; Shimoda, Masayuki; D Stegall, Mark; G Stock, Peter; Vantyghem, Marie-Christine; Ventura-Aguiar, Pedro; H Wassmer, Charles; Webster, Angela; White, Steve; Witkowski, Piotr; Wojtusciszyn, Anne; Wszola, Michal; Yoon, Kun-Ho. - In: TRANSPLANT INTERNATIONAL. - ISSN 1432-2277. - 35:(2022), p. 10507. [10.3389/ti.2022.10507]

A Worldwide Survey of Activities and Practices in Clinical Islet of Langerhans Transplantation

Federico Bertuzzi;Paola Maffi;Lorenzo Piemonti;
2022-01-01

Abstract

A global online survey was administered to 69 islet transplantation programs, covering 84 centers and 5 networks. The survey addressed questions on program organization and activity in the 2000-2020 period, including impact on activity of national health care coverage policies. We obtained full data from 55 institutions or networks worldwide and basic activity data from 6 centers. Additional data were obtained from alternative sources. A total of 94 institutions and 5 networks was identified as having performed islet allotransplantation. 4,365 islet allotransplants (2,608 in Europe, 1,475 in North America, 135 in Asia, 119 in Oceania, 28 in South America) were reported in 2,170 patients in the survey period. From 15 centers active at the start of the study period, the number of simultaneously active islet centers peaked at 54, to progressively decrease to 26 having performed islet allotransplants in 2020. Notably, only 16 centers/networks have done >100 islet allotransplants in the survey period. Types of transplants performed differed notably between North America and the rest of the world, in particular with respect to the near-absence of simultaneous islet-kidney transplantation. Absence of heath care coverage has significantly hampered transplant activity in the past years and the COVID-19 pandemic in 2020.
2022
IAK
ITA
SIK
activity
health care coverage
indications
islet transplantation
type 1 diabetes mellitus
Humans
Pandemics
COVID-19
Diabetes Mellitus, Type 1
Islets of Langerhans Transplantation
Pancreas Transplantation
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/137223
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