Rhabdomyosarcoma (RMS) represents more than 50% of paediatric soft tissue tumours. Conversely, it is extremely rare among adults, where it shows peculiar biological and clinical features that are still poorly investigated. RMS patients should be referred to a Sarcoma Centre, where the contribution of experienced radiologists plays a relevant role in the diagnostic assessment of the disease, including precise localisation, staging, image-guided biopsy, response evaluation after treatment and follow-up. Besides CT and MRI, hybrid imaging including positron emission tomography (PET)/CT and PET/MRI are giving an increasing contribution to provide functional insights about tumour biology and to improve the diagnostic accuracy of the imaging work-up. This review paper provides a revision of the pathology, clinical and radiological features of adult RMS, with a particular focus on the growing role of hybrid PET-based imaging.

Multimodality imaging of adult rhabdomyosarcoma: the added value of hybrid imaging / Gennaro, Nicolò; Marrari, Andrea; Renne, Salvatore Lorenzo; Cananzi, Ferdinando Carlo Maria; Quagliuolo, Vittorio Lorenzo; Di Brina, Lucia; Scorsetti, Marta; Pepe, Giovanna; Chiti, Arturo; Santoro, Armando; Balzarini, Luca; Politi, Letterio Salvatore; Bertuzzi, Alexia Francesca. - In: BRITISH JOURNAL OF RADIOLOGY. - ISSN 0007-1285. - 93:1112(2020). [10.1259/bjr.20200250]

Multimodality imaging of adult rhabdomyosarcoma: the added value of hybrid imaging

Chiti, Arturo;
2020-01-01

Abstract

Rhabdomyosarcoma (RMS) represents more than 50% of paediatric soft tissue tumours. Conversely, it is extremely rare among adults, where it shows peculiar biological and clinical features that are still poorly investigated. RMS patients should be referred to a Sarcoma Centre, where the contribution of experienced radiologists plays a relevant role in the diagnostic assessment of the disease, including precise localisation, staging, image-guided biopsy, response evaluation after treatment and follow-up. Besides CT and MRI, hybrid imaging including positron emission tomography (PET)/CT and PET/MRI are giving an increasing contribution to provide functional insights about tumour biology and to improve the diagnostic accuracy of the imaging work-up. This review paper provides a revision of the pathology, clinical and radiological features of adult RMS, with a particular focus on the growing role of hybrid PET-based imaging.
2020
Humans
Magnetic Resonance Imaging
Positron Emission Tomography Computed Tomography
Rhabdomyosarcoma
Soft Tissue Neoplasms
Tomography
X-Ray Computed
Multimodal Imaging
Humans
Magnetic Resonance Imaging
Positron Emission Tomography Computed Tomography
Rhabdomyosarcoma
Soft Tissue Neoplasms
Tomography
X-Ray Computed
Multimodal Imaging
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/140762
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