IRIS

Impact of lymphnode ratio and number of lymphnode metastases on survival and recurrence in laryngeal squamous carcinoma / Molteni, G.; Nocini, R.; Mattiolo, F.; Nakayama, M.; Dedivitis, R.; Mannelli, G.; Crosetti, E.; Chiesa -Estomba, C.; Sistiaga-Suarez, J.; Giordano, L.; Galli, A.; Lionello, M.; Mercante, G.; Ralli, M.; Fermi, M.; Rodriguez-Klein, A.; Mayo, M.; Serafini, E.; Pirola, F.; Paderno, A.; Cambria, F.; Oridate, N.; Sano, D.; Boscolo Rizzo, P.; Marcuzzo, A. V.; Parrinello, G.; Marchi, F.; Saibene, A. M.; Tucciatore, M.; Viscasillas, G.; Zelenik, K.; Ramos, D. M.; Palacios-Garcia, J.; Tirelli, G.; Pellini, R.; Paludetti, G.; Galli, J.; Rossi, G.; De Vincentis, M.; Cernea, C.; Spriano, G.; Bussi, M.; Peretti, G.; Succo, G.; Piazza, C.; Bertolin, A.; Kowalski, L.; Presutti, L.; Sacchetto, A.. - In: HEAD & NECK. - ISSN 1043-3074. - 45:9(2023), pp. 2274-2293. [10.1002/hed.27471]

Impact of lymphnode ratio and number of lymphnode metastases on survival and recurrence in laryngeal squamous carcinoma

Molteni G.
Primo
;Giordano L.;Galli A.;Rossi G.;Bussi M.;
2023-01-01
2023
Introduction: The aim of this study is to assess the impact of lymph node ratio (LNR) and number of positive lymph nodes (NPLN) on mortality and recurrence rates in patients with laryngeal squamous cell carcinoma. Materials and methods: We conducted a retrospective multicenter international study involving 24 Otorhinolaryngology-Head and Neck Surgery divisions. Disease-specific survival (DSS) and disease-free survival (DFS) were evaluated as the main outcomes. The curves for DSS and DFS according to NPLN and LNR were analyzed to identify significant variations and establish specific cut-off values. Results: 2507 patients met the inclusion criteria. DSS and DFS were significantly different in the groups of patients stratified according to LNR and NPLN. The 5-year DSS and DFS based on LNR and NPLN demonstrated an improved ability to stratify patients when compared to pN staging. Conclusion: Our data demonstrate the potential prognostic value of NPLN and LNR in laryngeal squamous cell carcinoma
laryngeal cancer; lymph node; lymph node metastasis; lymph node ratio; oncology
1.1 Articolo in rivista
File in questo prodotto:
File Dimensione Formato  
Head Neck - 2023 - Molteni - Impact of lymph node ratio and number of lymph node metastases on survival and recurrence in.pdf

solo gestori archivio

Tipologia: PDF editoriale (versione pubblicata dall'editore)
Licenza: Copyright dell'editore
Dimensione 2.78 MB
Formato Adobe PDF
  Visualizza/Apri   Richiedi una copia
2.78 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/148017
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 5
  • ???jsp.display-item.citation.isi??? 5
social impact