Among the most important theories of modern biological thought, the concept of immune self appeared as a tacit assumption in the speculations of cellular pathologists and physiologists in the second half of the Nineteenth century. Thanks to its first conceptualization advanced by Burnet in the 1950's, immune self gained the central stage during the "golden age of immunology" from 1960 to 1980, just to come up with a recent crisis because of its lack of explanatory power of emergent phenomena such as inflammatory and autoimmune diseases. The following discussion of the immune self history, together with a reassessment of recent experimental data, will suggest a further conceptual turn in the immune self theory that we propose to refer to as "Liquid Self".

The Immunological Self: A reappraisal / Tieri, P; Grignolio, A; Mishto, M; Franceschi, C. - 5:(2011), pp. 11-15. (Intervento presentato al convegno Sysbiohealth Symposium 2011. Systems Medicine: Interfacing Physics, Mathematics and Medicine tenutosi a Bologna nel 14 - 15 dicembre 2011).

The Immunological Self: A reappraisal

Grignolio A
Secondo
;
2011-01-01

Abstract

Among the most important theories of modern biological thought, the concept of immune self appeared as a tacit assumption in the speculations of cellular pathologists and physiologists in the second half of the Nineteenth century. Thanks to its first conceptualization advanced by Burnet in the 1950's, immune self gained the central stage during the "golden age of immunology" from 1960 to 1980, just to come up with a recent crisis because of its lack of explanatory power of emergent phenomena such as inflammatory and autoimmune diseases. The following discussion of the immune self history, together with a reassessment of recent experimental data, will suggest a further conceptual turn in the immune self theory that we propose to refer to as "Liquid Self".
2011
978-88-7395-696-9
Immune self
History of Immunology
Autoimmunity
File in questo prodotto:
File Dimensione Formato  
Tieri P., Grignolio A., Mishto M., Franceschi F._The Immunological Self. A Reappraisal_2011.pdf

solo gestori archivio

Tipologia: PDF editoriale (versione pubblicata dall'editore)
Licenza: Copyright dell'editore
Dimensione 680.55 kB
Formato Adobe PDF
680.55 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/150364
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact