Dealing with burnt bodies, the forensic pathologist must first of all answer the question whether the victim was alive at the moment of the fire. This study aims at clarifying whether some human solid tissues may be reliably used for the forensic diagnosis of Co poisoning on burnt bodies providing no collectable blood during the autopsy. From 34 selected cases, both cardiac blood and parenchymal samples were collected to perform CO-oxymeter, spectrophotometry, and gas chromatography tests: blood CO estimations (blood COHb% and blood[CO]) and parenchymal[CO] values have been compared with special focus on R values. The solid tissues having the best correlations with blood CO amount turned out to be the lung (R 0.84), the liver (R 0.83), the kidney (R 0.79), and the spleen (R 0.92).

How Reliable are Parenchymal Tissues for the Evaluation of Carbon Monoxide Poisoning? A Pilot Study / Casali, M. B.; Sironi, L.; MARINA CARLA, Caligara; Blandino, A.; Circelli, S.; Schiavi, D.; Cattaneo, C.. - In: JOURNAL OF FORENSIC SCIENCES. - ISSN 0022-1198. - 60:2(2015), pp. 488-494. [10.1111/1556-4029.12664]

How Reliable are Parenchymal Tissues for the Evaluation of Carbon Monoxide Poisoning? A Pilot Study

A. Blandino;
2015-01-01

Abstract

Dealing with burnt bodies, the forensic pathologist must first of all answer the question whether the victim was alive at the moment of the fire. This study aims at clarifying whether some human solid tissues may be reliably used for the forensic diagnosis of Co poisoning on burnt bodies providing no collectable blood during the autopsy. From 34 selected cases, both cardiac blood and parenchymal samples were collected to perform CO-oxymeter, spectrophotometry, and gas chromatography tests: blood CO estimations (blood COHb% and blood[CO]) and parenchymal[CO] values have been compared with special focus on R values. The solid tissues having the best correlations with blood CO amount turned out to be the lung (R 0.84), the liver (R 0.83), the kidney (R 0.79), and the spleen (R 0.92).
2015
Carbon monoxide intoxication
Carbonization
Forensic pathology
Forensic science
Parenchymal tissues
Postmortem forensic toxicology
Adult
Aged
Aged
80 and over
Brain Chemistry
Carbon Monoxide
Carbon Monoxide Poisoning
Chromatography
Gas
Female
Forensic Pathology
Humans
Kidney
Liver
Lung
Male
Middle Aged
Myocardium
Pilot Projects
Psoas Muscles
Spectrophotometry
Spleen
Subcutaneous Fat
2734
Genetics
Medicine (all)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/152023
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