Background: Gynaecological problems are often ignored by rheumatologist andhave a negative impact on quality of life of RDs patients.Objectives: The aim of this study was to describe gynaecological, reproductiveand sexual problems in premenopausal woman with RDs.Methods: A monocentric, cross-sectional observational study was conducted inthe Rheumatology Department of Careggi Hospital in Florence. Inclusion criteria:female gender, premenopausal age (and≥18 years old), diagnosis of rheumaticdiseases. All patients have been investigated about gynaecological anamnesisand symptoms and subjected to a self-administered validated questionnaire.Results: From May 4 th to November 30th, 2020, 200 patients were enrolled(mean age 39.1± 8.7 years (M±SD)): 58% arthritis, 40% connective tissue disease and 1.5% systemic vasculitis. In the history, spontaneous, full-term birth in91% and 93% of patients, respectively, was observed and pre-term birth wasreported in 8.1%. 63% of patients were breastfed. In family history, menorrhagia, dysmenorrhea, or chronic pelvic pain were reported in 59%, 55 and 7% ofpatients, respectively. The first menstruation was at 12.3±2.0 years (M±DS) andmostly woman reported menstrual disorders during adolescence (56% experienced dysmenorrhea and 52% menorrhagia). Menstrual disorders and abnormalbleeding were frequently reported also in adulthood: 71% had dysmenorrhea,38% heavy menstrual cycles and 9% metrorrhagia. Moreover, 26% of patientsreferred non- menstrual pelvic pain, 19% urinary pain and 18% pain during defecation. Vaginal symptoms were frequently reported: 36% of patients referredvaginal dryness, 29% burning, 19% recurrent vaginal infections and dyspareuniain 39% of patients. Uterine fibroma was present in 23% and endometriosis in10% of patients. Fertility problems were reported by 10% of patients in a timeframe of 7.5±6.4 years and 30% of patients experienced at least one miscarriage;otherwise, 56% of patients have had at least one full-term pregnancy.Conclusion: RDs patients show a high prevalence of various gynaecologicalproblems affecting their quality of life. The management of female RDs patientsis a challenge for the clinician and should include an accurate evaluation of thegynaecological aspects (menstruation, fertility, maternity, sexuality) as well as amultidisciplinary teamwork (rheumatologist and gynaecologists).

THE FIRST 1000 DAYS OF LIFE AND REPRODUCTIVE DISORDERS IN WOMAN WITH RHEUMATIC DISEASE (RDS) / Orlandi, M; Vannuccini, S; El Aoufy, K; Melis, Mr; Lepri, G; Bellando-Randone, S; Guiducci, S; Matucci Cerinic, M; Petraglia, F. - In: ANNALS OF THE RHEUMATIC DISEASES. - ISSN 0003-4967. - 80:(2021), pp. 1192-1192. [10.1136/annrheumdis-2021-eular.3282]

THE FIRST 1000 DAYS OF LIFE AND REPRODUCTIVE DISORDERS IN WOMAN WITH RHEUMATIC DISEASE (RDS)

Matucci Cerinic, M
Penultimo
;
2021-01-01

Abstract

Background: Gynaecological problems are often ignored by rheumatologist andhave a negative impact on quality of life of RDs patients.Objectives: The aim of this study was to describe gynaecological, reproductiveand sexual problems in premenopausal woman with RDs.Methods: A monocentric, cross-sectional observational study was conducted inthe Rheumatology Department of Careggi Hospital in Florence. Inclusion criteria:female gender, premenopausal age (and≥18 years old), diagnosis of rheumaticdiseases. All patients have been investigated about gynaecological anamnesisand symptoms and subjected to a self-administered validated questionnaire.Results: From May 4 th to November 30th, 2020, 200 patients were enrolled(mean age 39.1± 8.7 years (M±SD)): 58% arthritis, 40% connective tissue disease and 1.5% systemic vasculitis. In the history, spontaneous, full-term birth in91% and 93% of patients, respectively, was observed and pre-term birth wasreported in 8.1%. 63% of patients were breastfed. In family history, menorrhagia, dysmenorrhea, or chronic pelvic pain were reported in 59%, 55 and 7% ofpatients, respectively. The first menstruation was at 12.3±2.0 years (M±DS) andmostly woman reported menstrual disorders during adolescence (56% experienced dysmenorrhea and 52% menorrhagia). Menstrual disorders and abnormalbleeding were frequently reported also in adulthood: 71% had dysmenorrhea,38% heavy menstrual cycles and 9% metrorrhagia. Moreover, 26% of patientsreferred non- menstrual pelvic pain, 19% urinary pain and 18% pain during defecation. Vaginal symptoms were frequently reported: 36% of patients referredvaginal dryness, 29% burning, 19% recurrent vaginal infections and dyspareuniain 39% of patients. Uterine fibroma was present in 23% and endometriosis in10% of patients. Fertility problems were reported by 10% of patients in a timeframe of 7.5±6.4 years and 30% of patients experienced at least one miscarriage;otherwise, 56% of patients have had at least one full-term pregnancy.Conclusion: RDs patients show a high prevalence of various gynaecologicalproblems affecting their quality of life. The management of female RDs patientsis a challenge for the clinician and should include an accurate evaluation of thegynaecological aspects (menstruation, fertility, maternity, sexuality) as well as amultidisciplinary teamwork (rheumatologist and gynaecologists).
2021
REPRODUCTIVE DISORDERS
rheumatic diseases
File in questo prodotto:
File Dimensione Formato  
1192.2.full.pdf

solo gestori archivio

Tipologia: PDF editoriale (versione pubblicata dall'editore)
Licenza: Copyright dell'editore
Dimensione 159.8 kB
Formato Adobe PDF
159.8 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/154156
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? 0
social impact