Involvement of the right heart-pulmonary circulation system in systemic sclerosis is a typical feature, with critical prognostic implications. Pulmonary hypertension may occur in association with interstitial lung disease or as a result of an isolated pulmonary vascular disease that may affect both the precapillary arterioles and the postcapillary venules, as well as a consequence of left heart involvement. These apparently different phenotypes often underlie a significant pathophysiologic overlap, which makes the diagnosis and management of these patients highly complex and uncertain
Pulmonary Circulation on the Crossroads Between the Left and Right Heart in Systemic Sclerosis: A Clinical Challenge for Cardiologists and Rheumatologists / Gargani, L., Voilliot, D., D'Alto, M., Agoston, G., Moreo, A., Serra, W., Pieri, F., Mori, F., Wierzbowska-Drabik, K., Matucci-Cerinic, M., Moggi-Pignone, A.. - In: HEART FAILURE CLINICS. - ISSN 1551-7136. - 14:(2018), pp. 271-281. [10.1016/j.hfc.2018.02.004]
Pulmonary Circulation on the Crossroads Between the Left and Right Heart in Systemic Sclerosis: A Clinical Challenge for Cardiologists and Rheumatologists
Matucci-Cerinic, Marco;
2018-01-01
Abstract
Involvement of the right heart-pulmonary circulation system in systemic sclerosis is a typical feature, with critical prognostic implications. Pulmonary hypertension may occur in association with interstitial lung disease or as a result of an isolated pulmonary vascular disease that may affect both the precapillary arterioles and the postcapillary venules, as well as a consequence of left heart involvement. These apparently different phenotypes often underlie a significant pathophysiologic overlap, which makes the diagnosis and management of these patients highly complex and uncertainI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
