Involvement of the right heart-pulmonary circulation system in systemic sclerosis is a typical feature, with critical prognostic implications. Pulmonary hypertension may occur in association with interstitial lung disease or as a result of an isolated pulmonary vascular disease that may affect both the precapillary arterioles and the postcapillary venules, as well as a consequence of left heart involvement. These apparently different phenotypes often underlie a significant pathophysiologic overlap, which makes the diagnosis and management of these patients highly complex and uncertain
Pulmonary Circulation on the Crossroads Between the Left and Right Heart in Systemic Sclerosis: A Clinical Challenge for Cardiologists and Rheumatologists / Gargani, Luna; Voilliot, Damien; D'Alto, Michele; Agoston, Gergely; Moreo, Antonella; Serra, Walter; Pieri, Francesco; Mori, Fabio; Wierzbowska-Drabik, Karina; Matucci-Cerinic, Marco; Moggi-Pignone, Alberto. - In: HEART FAILURE CLINICS. - ISSN 1551-7136. - 14:(2018), pp. 271-281. [10.1016/j.hfc.2018.02.004]
Pulmonary Circulation on the Crossroads Between the Left and Right Heart in Systemic Sclerosis: A Clinical Challenge for Cardiologists and Rheumatologists
Matucci-Cerinic, Marco;
2018-01-01
Abstract
Involvement of the right heart-pulmonary circulation system in systemic sclerosis is a typical feature, with critical prognostic implications. Pulmonary hypertension may occur in association with interstitial lung disease or as a result of an isolated pulmonary vascular disease that may affect both the precapillary arterioles and the postcapillary venules, as well as a consequence of left heart involvement. These apparently different phenotypes often underlie a significant pathophysiologic overlap, which makes the diagnosis and management of these patients highly complex and uncertainI documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
