Chikungunya virus (CHIKV) appeared for the first time in the Western Hemisphere-the French West Indies-in December of 2013. From there, the virus has spread to other Caribbean islands. Following the diagnosis of first autochthonous CHIKV cases in the Caribbean island of Saint Martin, a large outbreak is ongoing in the Americas. As of September 12, 2014, a total of 706,093 suspected and 9803 confirmed CHIKV cases have been reported in the Americas. This case study highlights the possibility of false-negative immunochromatographic CHIKV immunoglobulin M (IgM) tests and the need of confirmatory tests for suspected cases. Moreover, a greater spread of virus together with the presence of a mosquito vector (Aedes albopictus) enhances the risk of autochthonous transmission in Europe.
Chikungunya from the Caribbean: The Importance of Appropriate Laboratory Tests to Confirm the Diagnosis / Magurano, F; Zammarchi, L; Baggieri, M; Fortuna, C; Farese, A; Benedetti, E; Fiorentini, C; Rezza, G; Nicoletti, L; Bartoloni, A. - In: VECTOR BORNE AND ZOONOTIC DISEASES. - ISSN 1530-3667. - 15:4(2015), pp. 258-260. [10.1089/vbz.2014.1724]
Chikungunya from the Caribbean: The Importance of Appropriate Laboratory Tests to Confirm the Diagnosis
Rezza G;
2015-01-01
Abstract
Chikungunya virus (CHIKV) appeared for the first time in the Western Hemisphere-the French West Indies-in December of 2013. From there, the virus has spread to other Caribbean islands. Following the diagnosis of first autochthonous CHIKV cases in the Caribbean island of Saint Martin, a large outbreak is ongoing in the Americas. As of September 12, 2014, a total of 706,093 suspected and 9803 confirmed CHIKV cases have been reported in the Americas. This case study highlights the possibility of false-negative immunochromatographic CHIKV immunoglobulin M (IgM) tests and the need of confirmatory tests for suspected cases. Moreover, a greater spread of virus together with the presence of a mosquito vector (Aedes albopictus) enhances the risk of autochthonous transmission in Europe.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
