Combined Hepatocellular-Cholangiocarcinoma is a heterogenous primary malignant epithelial tumor of the liver with variable morphological and immunophenotypical features. Although the biology of this tumor has been described in the literature, changes in classification and its heterogeneity imply difficulties in collecting reliable homogenous groups to compare. The article aims to review available data on morphology and immunohistochemistry for practicing pathologists integrated with original data from our referral Center

Combined hepatocellular-cholangiocarcinoma: morpho-molecular updates and considerations / Ahmed, Naghia; Falcinelli, Francesca; Rimini, Margherita; Burgio, Valentina; Casadei-Gardini, Andrea; Aldrighetti, Luca; Ratti, Francesca; Pedica, Federica. - In: HEPATOMA RESEARCH. - ISSN 2394-5079. - 9:(2023). [10.20517/2394-5079.2022.81]

Combined hepatocellular-cholangiocarcinoma: morpho-molecular updates and considerations

Ahmed, Naghia
Primo
;
Falcinelli, Francesca
Secondo
;
Rimini, Margherita;Casadei-Gardini, Andrea;Aldrighetti, Luca;Ratti, Francesca
Penultimo
;
Pedica, Federica
Ultimo
2023-01-01

Abstract

Combined Hepatocellular-Cholangiocarcinoma is a heterogenous primary malignant epithelial tumor of the liver with variable morphological and immunophenotypical features. Although the biology of this tumor has been described in the literature, changes in classification and its heterogeneity imply difficulties in collecting reliable homogenous groups to compare. The article aims to review available data on morphology and immunohistochemistry for practicing pathologists integrated with original data from our referral Center
2023
Combined hepatocellular-cholangiocarcinoma, immunohistochemistry, molecular analyses, WHO classification
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/163416
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