Purpose: To describe a case of bilateral panuveitis in a patient with Stimulator of Interferon Genes (STING)- Associated Vasculitis with Onset in Infancy (SAVI). Observations: A 45-year-old patient diagnosed with SAVI presented bilateral panuveitis and uncontrolled sec- ondary intraocular hypertension due to structural complications from uveitis. Multimodal imaging revealed the presence of intraretinal fluid and bilateral vasculitis. The patient was started with systemic methotrexate. Conclusions and importance: This case is essential to characterize ocular involvement in patients with SAVI. Awareness of these ocular manifestations is crucial for timely management and improvement of visual prognosis.

Ocular complications of SAVI: A unique case of bilateral uveitis and retinal vasculitis / Menean, Matteo; Marchese, Alessandro; Modorati, Giulio; Favale, Rosa; Boscia, Francesco; Bandello, Francesco; Miserocchi, Elisabetta. - In: AMERICAN JOURNAL OF OPHTHALMOLOGY. CASE REPORTS. - ISSN 2451-9936. - 34:(2024). [10.1016/j.ajoc.2024.102046]

Ocular complications of SAVI: A unique case of bilateral uveitis and retinal vasculitis

Menean Matteo
Primo
;
Marchese Alessandro
Secondo
;
Bandello Francesco
Penultimo
;
MISEROCCHI Elisabetta
Ultimo
2024-01-01

Abstract

Purpose: To describe a case of bilateral panuveitis in a patient with Stimulator of Interferon Genes (STING)- Associated Vasculitis with Onset in Infancy (SAVI). Observations: A 45-year-old patient diagnosed with SAVI presented bilateral panuveitis and uncontrolled sec- ondary intraocular hypertension due to structural complications from uveitis. Multimodal imaging revealed the presence of intraretinal fluid and bilateral vasculitis. The patient was started with systemic methotrexate. Conclusions and importance: This case is essential to characterize ocular involvement in patients with SAVI. Awareness of these ocular manifestations is crucial for timely management and improvement of visual prognosis.
2024
Interferonopathy; SAVI; STING; Uveitis; Vasculitis
File in questo prodotto:
File Dimensione Formato  
Savi syndrome .pdf

accesso aperto

Tipologia: PDF editoriale (versione pubblicata dall'editore)
Licenza: Creative commons
Dimensione 3.18 MB
Formato Adobe PDF
3.18 MB Adobe PDF Visualizza/Apri

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/165376
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 0
  • ???jsp.display-item.citation.isi??? ND
social impact