Background: No robust data are available on the safety of primary bariatric and metabolic surgery (BMS) alone compared to primary BMS combined with other procedures. Objectives: The objective of this study is to collect a 30-day mortality and morbidity of primary BMS combined with cholecystectomy, ventral hernia repair, or hiatal hernia repair. Setting: This is as an international, multicenter, prospective, and observational audit of patients undergoing primary BMS combined with one or more additional procedures. Methods: The audit took place from January 1 to June 30, 2022. A descriptive analysis was conducted. A propensity score matching analysis compared the BLEND study patients with those from the GENEVA cohort to obtain objective evaluation between combined procedures and primary BMS alone. Results: A total of 75 centers submitted data on 1036 patients. Sleeve gastrectomy was the most commonly primary BMS (N = 653, 63%), and hiatal hernia repair was the most commonly concomitant procedure (N = 447, 43.1%). RYGB accounted for the highest percentage (20.6%) of a 30-day morbidity, followed by SG (10.5%). More than one combined procedures had the highest morbidities among all combinations (17.1%). Out of overall 134 complications, 129 (96.2%) were Clavien-Dindo I–III, and 4 were CD V. Patients who underwent a primary bariatric surgery combined with another procedure had a pronounced increase in a 30-day complication rate compared with patients who underwent only BMS (12.7% vs. 7.1%). Conclusion: Combining BMS with another procedure increases the risk of complications, but most are minor and require no further treatment. Combined procedures with primary BMS is a viable option to consider in selected patients following multi-disciplinary discussion. Graphical Abstract: (Figure presented.)
Global 30-Day Morbidity and Mortality of Primary Bariatric Surgery Combined with Another Procedure: The BLEND Study / Martinino, A.; Nanayakkara, K. D. L.; Madhok, B.; Wong, G. Y. M.; Abouelazayem, M.; Pereira, J. P. S.; Wazir, I.; Balasubaramaniam, V.; Said, A.; Marques, C.; Abdelbaeth, A.; Al-Shami, K.; Albashari, M.; Alkaseek, A.; Almayouf, M. A.; Aloulou, M.; Alqahtan, A. R.; Askari, A.; Attia, M. F. A.; Awad, A. K.; Aykota, M. R.; Bacalbasa, N.; Barrera-Rodriguez, F. J.; Benavoli, D.; Billa, S.; Borrelli, V.; Calikoglu, I.; Campanelli, M.; Carbajo, M. A.; Chowdhury, S.; Cristin, L.; Dapri, G.; Dong, Z.; Elfawal, M. H.; Elgazar, A.; Elhadi, M.; Gentileschi, P.; Graham, Y.; Haj, B.; Johnson, J. A.; Kalmoush, A. -E. M.; Kamal, A.; Kamocka, A.; Khamees, A.; Lisi, G.; Hernandez, E. E. L.; Marinari, G. M.; Martines, G.; Meric, S.; Mier, F.; Ali, A. M.; Mohammed, D.; Mohamed, K. M.; Mulita, F.; Musella, M.; O'Malley, W. E.; Olmi, S.; Omarov, T.; Osama, O.; Perera, H. R.; Piscitelli, G.; Poghosyan, T.; Ramirez, D.; Rezvani, M.; Ribeiro, R.; Sabbota, A.; Sakran, N.; Sawaftah, K. A.; Schiavone, K.; Sen, O.; Sotiropoulou, M.; Tartaglia, N.; Tokocin, M.; Trotta, M.; Turkcapar, A. G.; Uccelli, M.; Vargas, C.; Verras, G. I.; Wang, C.; Wei, Z.; Yang, W.; Zerrweck, C.; Owen, E.; Gkoutos, G. V.; Cardoso, V. R.; Singhal, R.; Mahawar, K.; Pinto, F.; Homayoon, ; Zuluaga, M.; Zengin, K.; Zayat, H.; Yuksel, S.; Yeoh, B.; Wietzycoski, C. R.; Wang, H.; Waledziak, M.; Voon, K.; Viveiros, O.; Uludag, S. S.; Ulhaq, M. B.; Ucar, E. R.; Toro-Huamanchumo, C. T.; Tidjane, A.; Thapar, P. M.; Tay, S.; Taha, S.; Sylvester, K. R.; So, J. B. Y.; Shariff, A. H.; Shahzad, A.; Shabbir, A.; Shabbir, A.; Sawas, M. N.; Sawaftah, M. A.; Sawaftah, M. A.; Sarodaya, V.; Santos, C. S. F.; Salvi, P. H.; Saleh, F. S.; Ramu, G.; Rajeev, Y.; Pintar, T.; Petkov, P.; Pavone, G.; Parmar, C.; Paranyak, M.; Ozmen, M.; Ozcelik, M. F.; Ouadii, M.; Omari, A.; Niazi, M.; Neimark, A.; Negoi Negoi, I.; Nashidengo, P. A.; Nasani, M.; Nabais, C.; Montes, N. M.; Mousafeiris, V.; Mohammed, A.; Mbonicura, J. C.; Masri, R.; Marom, G. A.; Mamidanna, R.; Mahdi, A. S.; Mahafdah, M. R.; Magnani, R.; Lincango Naranjo, E. P.; Liakopulos, N. J.; Lepiane, P.; Lazaros, L.; Kraljik, D.; Di Pangrazio, M.; Toti, F.; Kosir, J. A.; Klib, M.; Kim, G.; Khan, S.; Kermansaravi, M.; Kayyal, M. Y.; Kayali, A. A. H.; Kassir, R.; Kasi, S. K.; Kapiris, S.; Inam, A.; Ibrahim, H.; Houssem, A.; Hong, J.; Hazebroek, E.; Hamid, H. K. S.; Haj, M.; Gunawardene, A.; Goodman, E.; Viswanath, N. G.; Gil, I.; Gianchandani-Moorjani, R.; Ghazal, R.; Ghazal, A.; Ghareeb, S.; Gfely, R.; Genser, L.; Frattini, F.; Fishman, Y.; Fischer, L. E.; Erginoz, E.; Erdene, S.; Elhafiz, H.; Elghrieb, A. E.; Elghadban, H. M.; Duro, A.; Dulac, A. S.; Dogjani, A.; Diaz, A.; Demma, J. A.; De Leon Ballesteros, G. P.; Daskalakis, M.; Dash, A. K.; Colak, E.; Chokshi, A.; Chia, D. K. A.; Cethorth Fonseca, R. K.; Caruana, C.; Cano Busnelli, V. M.; Budihal, B. R.; Borges, N.; Boligo, S. L.; Bhasker, A. G.; Berardi, G.; Bello, U. M.; Bani Hani, L. M.; Bani Hani, Z. M.; Hani, M. B.; Balla, A.; Balescu, I.; Baksi, A.; Bakeer, H. B.; Awadi, S.; Awad, A.; Assaf, A.; Arraf, J.; Arnaout, A. Y.; Antozzi, L.; Ammar, A. Y.; Amaral, P. F. N.; Alsheikh, A. M.; Alshareea, E. A.; Alrayes, B. M. H.; Aloulou, M.; Allawgalli, A. N.; Allahverdiyeva, N.; Alabdallah, N. B.; Al-Taan, O.; Al-Shami, M.; Al-Qazakzeh, H. I.; Al-Naggar, H.; Al-issawi, S. Z.; AL Hamoud, M. A.; Ahmed, F.; Adeyeye, A. A.; Abouleid, A.; Abou-Mrad, A. K.; Abdulwahed, E. A.; Abdelhamid Abdelhamid, I.. - In: OBESITY SURGERY. - ISSN 0960-8923. - 34:11(2024), pp. 4152-4165. [10.1007/s11695-024-07296-0]
Global 30-Day Morbidity and Mortality of Primary Bariatric Surgery Combined with Another Procedure: The BLEND Study
Olmi S.;Pavone G.;
2024-01-01
Abstract
Background: No robust data are available on the safety of primary bariatric and metabolic surgery (BMS) alone compared to primary BMS combined with other procedures. Objectives: The objective of this study is to collect a 30-day mortality and morbidity of primary BMS combined with cholecystectomy, ventral hernia repair, or hiatal hernia repair. Setting: This is as an international, multicenter, prospective, and observational audit of patients undergoing primary BMS combined with one or more additional procedures. Methods: The audit took place from January 1 to June 30, 2022. A descriptive analysis was conducted. A propensity score matching analysis compared the BLEND study patients with those from the GENEVA cohort to obtain objective evaluation between combined procedures and primary BMS alone. Results: A total of 75 centers submitted data on 1036 patients. Sleeve gastrectomy was the most commonly primary BMS (N = 653, 63%), and hiatal hernia repair was the most commonly concomitant procedure (N = 447, 43.1%). RYGB accounted for the highest percentage (20.6%) of a 30-day morbidity, followed by SG (10.5%). More than one combined procedures had the highest morbidities among all combinations (17.1%). Out of overall 134 complications, 129 (96.2%) were Clavien-Dindo I–III, and 4 were CD V. Patients who underwent a primary bariatric surgery combined with another procedure had a pronounced increase in a 30-day complication rate compared with patients who underwent only BMS (12.7% vs. 7.1%). Conclusion: Combining BMS with another procedure increases the risk of complications, but most are minor and require no further treatment. Combined procedures with primary BMS is a viable option to consider in selected patients following multi-disciplinary discussion. Graphical Abstract: (Figure presented.)I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.