A prognostic scoring system based on laboratory inflammation parameters, [Hemo-Eosinophils-Inflammation (HEI) index], including baseline hemoglobin level, the systemic inflammatory index and eosinophil count was recently proposed in patients with squamous cell carcinoma of the anus (ASCC). HEI was shown to discriminate disease-free (DFS) and overall (OS) survival in ASCC patients treated with concurrent chemoradiation (CRT). We tested the accuracy of the model on a multicentric cohort for external validation.

External validation of a composite bio-humoral index in anal cancer patients undergoing concurrent chemoradiation / Franco, P., Porreca, A., Mantello, G., Valvo, F., Gasparini, L., Slim, N., Manfrida, S., De Felice, F., Gerardi, M.A., Vagge, S., Krengli, M., Palazzari, E., Osti, M.F., Gonnelli, A., Catalano, G., Pittoni, P., Ivaldi, G.B., Lupattelli, M., Rosetto, M.E., Niespolo, R.M., et al.. - In: RADIOTHERAPY AND ONCOLOGY. - ISSN 0167-8140. - 177:(2022), pp. 9-15. [10.1016/j.radonc.2022.10.015]

External validation of a composite bio-humoral index in anal cancer patients undergoing concurrent chemoradiation

Casadei Gardini, Andrea;
2022-01-01

Abstract

A prognostic scoring system based on laboratory inflammation parameters, [Hemo-Eosinophils-Inflammation (HEI) index], including baseline hemoglobin level, the systemic inflammatory index and eosinophil count was recently proposed in patients with squamous cell carcinoma of the anus (ASCC). HEI was shown to discriminate disease-free (DFS) and overall (OS) survival in ASCC patients treated with concurrent chemoradiation (CRT). We tested the accuracy of the model on a multicentric cohort for external validation.
2022
Anal cancer
Concurrent Chemo-radiation
Hemo-Eosinophils-Inflammation Index
Prognosis
Radiotherapy
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/184296
Citazioni
  • ???jsp.display-item.citation.pmc??? 5
  • Scopus 5
  • ???jsp.display-item.citation.isi??? 5
social impact