A prognostic scoring system based on laboratory inflammation parameters, [Hemo-Eosinophils-Inflammation (HEI) index], including baseline hemoglobin level, the systemic inflammatory index and eosinophil count was recently proposed in patients with squamous cell carcinoma of the anus (ASCC). HEI was shown to discriminate disease-free (DFS) and overall (OS) survival in ASCC patients treated with concurrent chemoradiation (CRT). We tested the accuracy of the model on a multicentric cohort for external validation.
External validation of a composite bio-humoral index in anal cancer patients undergoing concurrent chemoradiation / Franco, Pierfrancesco; Porreca, Annamaria; Mantello, Giovanna; Valvo, Francesca; Gasparini, Lucrezia; Slim, Najla; Manfrida, Stefania; De Felice, Francesca; Gerardi, Marianna A; Vagge, Stefano; Krengli, Marco; Palazzari, Elisa; Osti, Mattia Falchetto; Gonnelli, Alessandra; Catalano, Gianpiero; Pittoni, Patrizia; Ivaldi, Giovani B; Lupattelli, Marco; Rosetto, Maria Elena; Niespolo, Rita Marina; Guido, Alessandra; Durante, Oreste; Macchia, Gabriella; Munoz, Fernando; El Khouzai, Badr; Lucido, Maria Rosaria; Arcadipane, Francesca; Casadei Gardini, Andrea; Maria D'Angelillo, Rolando; Gambacorta, Maria Antonietta; Genovesi, Domenico; Di Nicola, Marta; Caravatta, Luciana. - In: RADIOTHERAPY AND ONCOLOGY. - ISSN 0167-8140. - 177:(2022), pp. 9-15. [10.1016/j.radonc.2022.10.015]
External validation of a composite bio-humoral index in anal cancer patients undergoing concurrent chemoradiation
Casadei Gardini, Andrea;
2022-01-01
Abstract
A prognostic scoring system based on laboratory inflammation parameters, [Hemo-Eosinophils-Inflammation (HEI) index], including baseline hemoglobin level, the systemic inflammatory index and eosinophil count was recently proposed in patients with squamous cell carcinoma of the anus (ASCC). HEI was shown to discriminate disease-free (DFS) and overall (OS) survival in ASCC patients treated with concurrent chemoradiation (CRT). We tested the accuracy of the model on a multicentric cohort for external validation.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
