Assessment of letrozole and tamoxifen alone and in sequence for postmenopausal women with steroid hormone receptor-positive breast cancer: the BIG 1-98 randomised clinical trial at 8·1 years median follow-up

Regan MM;Neven P;Giobbie-Hurder A;Goldhirsch A;Ejlertsen B;Mauriac L;Forbes JF;Smith I;Láng I;Wardley A;Rabaglio M;Price KN;Gelber RD;Coates AS;Thürlimann B;BIG 1-98 Collaborative Group;International Breast Cancer Study Group (IBCSG) (Thürlimann B;Aebi S;Blacher L;Bonnefoi H;Coates A;Cufer T;Ejlertsen B;Forbes J;Gelber R;Giobbie-Hurder A;Goldhirsch A;Hiltbrunner A;Holmberg S;Maibach R;Martoni A;Mauriac L;MacGrogan G;Mouridsen H;Paridaens R;Phuong D;Price K;Rabaglio M;Rasmussen BB;Regan MM;Santoro A;Smith I;Wardley A;Viale G;Chaudri-Ross H;Segal S;Aebi S;Coates A;Colleoni M;Collins J;Cortés Funes H;Gelber R;Goldhirsch A;Green M;Hiltbrunner A;Holmberg S;Karlsson P;Kössler I;Láng I;Lindtner J;Paganetti F;de Stoppani M;Rudenstam C-;Senn H-;Stahel R;Thürlimann B;Veronesi A;Castiglione M;Hiltbrunner A;Rabaglio M;Egli G;Hawle H;Cliffe B;Ribeli-Hofmann S;Munarini F;Kammler R;Studer R;Ruepp B;Maibach R;Munarini N;Gelber R;Regan MM;Price K;Giobbie-Hurder A;Keshaviah A;Litman H;Cole BF;Sun Z;Gray PK;Huang H;Somos L;Timmers B;Nickerson L;Blacher L;Heckman Scolese T;Belisle M;Caporale M;Celano J;Dalfonso L;Dooley L;Fischer S;Galloway K;Gould J;Hinkle R;Holody M;Jones G;Krall R;Lippert S;Meshulam J;Mundy L;Pavlov-Shapiro A;Scott K;Scott M;Shepard S;Swick J;Uhteg L;Weinbaum D;Westby C;Zielinski T;Gusterson B;Mallon E;Viale G;Dell'Orto P;Mastropasqua M;Del Curto B;Waldie E;van Hoomissen I;De Smet M;Trostmann U;Schmidt W;Bolton A;Hackl W;Snyder R;Chirgwin J;Forbes J;Coates A;Boyle F;Lindsay D;Preece D;Cowell J;Talbot D;Whipp A;Abell F;Basser R;Bell R;Brady B;Blakey D;Briggs P;Burns I;Campbell P;Chao M;Chirgwin J;Chua B;Clarke K;Collins J;De Boer R;Din J;Doig R;Dowling A;Drummond R;Efe N;Fan S;Francis M;Francis P;Ganju V;Gibbs P;Goss G;Green M;Gregory P;Griffiths J;Haines I;Henderson M;Holmes R;James P;Kiffler J;Lehman M;Leyden M;Lim L;Lindeman G;Lynch R;Mann B;McKendrick J;McLachlan S;McLennan R;Mitchell G;Mitra S;Murphy C;Parker I;Phillips K;Porter I;Richardson G;Scarlet J;Sewak S;Shapiro J;Snyder R;Stanley R;Steer C;Stoney D;Strickland A;Toner G;Underhill C;White K;White M;Wirth A;Wong S;Holman Clinic WP;Byram D;Byard I;Della-Fiorentina S;Goldrick A;Hovey E;Moylan E;Segelov E;Chan A;Buck M;Hastrich D;Ingram D;Van Hazel G;Willsher P;Wilcken N;Crombie C;Forbes J;Abell F;Ackland S;Bonaventura A;Cox S;Denham J;Gourlay R;Jackson D;Sillar R;Stewart J;Lewis C;Brigham B;Goldstein D;Friedlander M;Walpole E;Thompson D;Gill P;Bochner M;Coventry J;Kollias J;Malycha P;Olver I;Colosimo M;Cheuk R;Kenny L;McCarthy N;Wyld D;Young R;Harrup R;Kimber R;Lowenthal R;Trotter J;Bayliss E;Chan A;Ransom D;Byrne M;Buck M;Dewar J;Nowak A;Powell A;Van Hazel G;Abdi E;Brodribb R;Volobueva Z;Harnett P;Ahern V;Gurney H;Wilcken N;Harvey V;Evans B;Jones W;McCrystal M;Porter D;Thompson P;Vaughan M;Gibbs D;Atkinson C;Burcombe R;Fitzharris B;Hickey B;Jeffery M;Robinson B;McLaren B;Costello S;North J;Perez D;Campbell I;Gilbert L;Gannaway R;Jameson M;Kennedy I;Long J;Round G;Spellman L;Whittle D;Woolerton D;Menke C;Biazús J;Cericatto R;Cavalheiro J;Xavier N;Bittelbrunn A;Rabin E;Gutiérrez J;Arriagada R;Bronfman L;Zuñiga M;Gutiérrez J;Acevedo J;Torres S;León A;Salazar E;Soto Diaz L;Duval R;Oddeshede N;Venti M;Peña K;Puente L;Maidana V;Baeza R;Arriagada R;Olfos P;Solé J;Vinés E;Mariani C;Láng I;Hitre E;Szabó E;Horváth Z;Ganofszky E;Juhos E;Veronesi A;Crivellari D;Magri M;Buonadonna A;Coran F;Borsatti E;Candiani E;Massarut S;Roncadin M;Arcicasa M;Carbone A;Perin T;Gloghini A;Tondini C;Labianca R;Poletti P;Bettini A;Clerico M;Vincenti M;Malossi A;Seles E;Perfetti E;Sartorello B;Simoncini E;Marini G;Marpicati P;Farfaglia R;Bianchi A;Grigolato P;Lucini L;Frata P;Huscher A;Micheletti E;Fogazzi C;Medicina U;Artioli F;Cagossi K;Scaltriti L;Bandieri E;Botticelli L;Giovanardi G;Ravaioli A;Pasquini E;Rudnas B;Foghin L;Manzoni A;Visini M;Zavallone L;Ucci G;Colleoni M;Viale G;Veronesi P;Peruzzotti G;Corsetto L;Ghisini R;Renne G;Luini A;Orlando L;Torrisi R;Rocca A;De Pas T;Munzone E;Galimberti V;Zurrida S;Intra M;Nolé F;Orecchia R;Martinelli G;de Braud F;Goldhirsch A;Ravaioli A;Gianni L;Gome H;Cufer T;Pajk B;Cervek J;Werner I;Murray E;Govender D;Dalvie S;Erasmus T;Robertson B;Read B;Nel E;Toop J;Nedeva N;Panieri E;Vorobiof D;Chasen M;McMichael G;Mohammed C;Holmberg S;Holmberg S;Mattsson J;Sellström H;Lindberg B;Goldhirsch A;Herrmann R;Thürlimann B;Schönenberger A;Mingrone W;Honegger Ch;Bärtschi E;Neter M;Rederer M;Schär G;Rochlitz C;Herrmann R;Oertli D;Wight E;Moch H;Bernier J;Bronz L;Cavalli F;Gallerani E;Richetti A;Franzetti A;Conti-Beltraminelli M;Ghielmini M;Gyr T;Mauri S;Saletti P;Goldhirsch A;Pagani O;Graffeo R;Locatelli M;Longhi S;Rey PC;Ruggeri M;Zucca E;Wyss D;Mazzucchelli L;Pedrinis E;Rusca T;Aebi S;Fey M;Castiglione M;Rabaglio M;Aebi S;Fey M;Zuber M;Beck G;Aebi S;Fey M;Schönenberger R;Lüthi JM;Rauch D;Bonnefoi H;Egli F;Steiner R;Fehr P;Perey L;de Grandi P;Jeanneret W;Leyvraz S;Delaloye JF;Thürlimann B;Köberle D;Weisser F;Mattemann S;Müller A;Cerny T;Späti B;Höfliger M;Fürstenberger G;Bolliger B;Öhlschlegel C;Lorenz U;Bamert M;Kehl-Blank J;Vogel E;Thürlimann B;Hess D;Senn I;Köberle D;Ehrsam A;Nauer C;Öhlschlegel C;Kehl-Blank J;Vogel E;Widmer L;Häfner M;Pestalozzi B;Fehr M;Caduff R;Varga Z;Trüb R;Fink D;Bättig B;Buser K;Bürki N;Dieterle A;Hasler L;Mannhart-Harms M;Rageth C;Richner J;Spataro V;Umbricht M;Ellis P;Harris S;Akbar N;McVicars H;Lees C;Raman R;Crane G;Ejlertsen B;Mouridsen H;Mouridsen H;Jakobsen E;Cold S;Kamby C;Ewertz M;Vestlev PM;Andersen J;Grundtvig P;Sandberg E;Philip P;Madsen E;Moeller K;Haahr V;Johansson J;Mauriac L;Debled M;Bonnefoi H;Campo P;Larregain-Fournier D;Remy S;Auvray H;De Gislain C;Delille F;Porteret MC;Servent V;Chapoutier M;Tubiana-Mathieu N;Lavau-Denes S;Bosc P;Guastalla J;Bachelot T;Arbault C;Netter-Pinon G;Perrin V;Monnier A;Hammoud Y;Romieu G;Culine L;Pinosa V;Cany L;Maguire C;Daban A;Le Saux M;Grandon C;Kerbrat P;Catheline C;Veyret C;Jugieau E;Talon V;Le Mevel A;Maury S;Gladieff L;Lignon N;Dodwell D;Dodwell D;Joffe J;Drew P;Yorkshire W;Nejim A;Dodwell D;Horgan K;Lansdown M;Perren T;Coleman R;Campos D;Cóppola F;Martinez J;Freue M;Wainstein C;Zori Comba A;Cazap E;Roffo AH;Mickiewicz E;Mendez A;Balbiani L;Osuna A;Palazzo E;de Romedis M;Cagnolati S;Delfino C;Caccia G;de Angelis R;Fein L;Sala R;Nassurdi C;Berra A;Viroglio R;Blajman C;Requejo H;Silberman L;Birrell S;Eaton M;Hoffman C;Humeniuk V;Craft P;Stuart-Harris R;Yip D;Bell R;Abell F;Francis M;Kiffer J;Lynch R;McLennan R;White K;Green M;Basser R;Collins J;De Boer R;Din J;Efe N;Fan S;Lindeman G;Wong S;Green M;Basser R;Collins J;De Boer R;Din J;Efe N;Fan S;Lindeman G;Wong S;Stewart J;Abell F;Ackland S;Bonaventura A;Trotter J;Bayliss E;Chan A;Ransom D;Redfern A;de Souza P;Links M;Dalley D;Grygiel J;Ward R;Underhill C;Clarke K;Steer C;Walpole E;Thompson D;Nogaret J;Christiaens MR;Neven P;Paridaens R;Smeets A;Vergote I;Weltens C;Wildiers H;Focan C;Marcelis L;Etterbeek C;Kains J;Canon J-;André Vèsale C;Brohèe D;Gowing J;Yelle L;Dubé P;Vogel C;León Prieto M;Petrakova K;Palacova M;Demlova R;Siffnerova H;Fischer J;Bustova I;Kankova H;Pintova M;Vitek P;Abrahamova J;Kordikova D;Petruzelka L;Sedlackova E;Honova H;Heinrich B;Wischnik A;Oberhoff C;Schindler A;Münstedt K;Meyer D;Grosse R;Kölbl H;Schmidt W;Mink D;Jänicke F;Lück H;Dornoff W;Hoffmann G;Hackmann J;Bader W;Kahan Z;Pajkos G;Kristo K;Dank M;Nagykalnai T;Landherr L;Kner E;Kispál M;Dani Á;Martoni A;Zamagni C;Giaquinta S;Piana E;Mattioli R;Imperatori L;Santoro A;Carnaghi C;Rimassa L;Gasparini G;Sciarretta G;Morabito A;Barni S;Cazzaniga M;Cabiddu M;Puglisi F;Cellerino R;Antognoli S;Freddari F;Mantovani G;Massa E;Astara G;Segati R;Rosso R;Del Mastro L;Venturini M;Bighin C;Bajetta E;Zilembo N;Paleari D;Procopio G;Salvagni S;Perrone M;Franciosi V;Salvatore S;Catalano G;Luzi Fedeli S;Pinotti G;Giardina G;Vallini I;Massidda B;Ionta M;Deidda M;Nalli G;Sita G;Carreca I;Cucciarré S;Burgio D;Lombardo M;Pandoli G;Di Stefano P;Boni C;Bisagni G;Banzi M;Linarello P;Colosini G;Spasiano A;Caldonazzo A;Pacquola M;Sleeboom H;Rutten H;Luiten E;Roerdink HT;Roumen R;McLaren B;Costello S;North J;Perez D;Pfieffer M;Kennedy I;Campbell I;Gilbert L;Gannaway R;Jameson M;Long J;Round G;Spellman L;Whittle D;Woolerton D;Jassem J;Welnicka-Jaskiewicz M;Senkus-Konefka E;Matuszewska K;Koralewski P;Pernal J;Pienkowski T;Brewczynska E;Bauer-Kosinska B;Sienkiewicz-Kozlowska R;Jagiello-Gruszfeld A;Sudol K;Tujakowski J;Zurawski B;Pawlega J;Jablonska E;Zygulska A;Górnasiowa M;Filypczyk-Cisarz E;Pajak K;Damasceno M;Albano J;da Costa B;Costa L;Henriques A;Amaral H;Marques F;Komov D;Polikarpova S;Makhson A;Zabaznyi N;Vozny E;Dobrovolskaya N;Bolshakova S;Yurgina O;Emmanuel N;Korman D;Maslova I;Petrov NN;Semiglazov V;Ivanov V;Manikhas G;Dolmatov G;Apffelstaedt J;Eedes D;Slabber C;Coccia M;Maart K;Alés Martinez J;Aramburo P;Sánchez R;Rifa J;Martin J;Pérez-Carrión R;González Larriba J;Cubillo A;Jiménez M;Casado A;Fra J;Vieitez J;Esteban E;Lacave A;Wight E;Bartens S;Decio R;Güth U;Breitenstein U;Icli F;Dincol D;Baltali E;Ozisik Y;Topuz E;Basaran M;Aydiner A;Ozdedeli E;Harmancioglu O;Yilmaz A;Smith I;Thompson A;Wardley A;Hickish T;Neave F;Sabini G.)

2011-01-01