Background: Systemic sclerosis (SSc) is characterized by macro and microvasculopathy, including splanchnic circulation. Chronic mesenteric ischemia (CMI) is a potentially severe condition which can complicate SSc gastrointestinal vasculopathy. Doppler ultrasound (DUS) may be a non-invasive procedure for identifying CMI in symptomatic SSc patients. Objectives: To investigate the capacity of DUS to detect early CMI and the effect of the endovascular approach on CMI-related symptoms. Methods: DUS of splanchnic arteries was performed in symptomatic SSc patients, during routinary outpatient visits. Results: In 6 out of 72 SSc symptomatic patients, DUS suggested a splanchnic vessels stenosis which was confirmed by computed tomography angiography (CTA). After multidisciplinary evaluation in 3 patients a revascularization was performed. Three-monthly clinical and DUS follow-up was negative in all patients. Conclusion: CDU is a useful screening tool for CMI in SSc patients. Revascularization of stenotic mesenteric arteries seems to be a safe and effective procedure.
Doppler ultrasound unveils splanchnic arteries ischemia allowing early successful revascularization in symptomatic systemic sclerosis patients / Bandini, G.; Campochiaro, C.; Ciuti, G.; Baccellieri, D.; Ardita, V.; Bellando Randone, S.; El Aoufy, K.; Giuggioli, D.; Orlandi, M.; Dagna, L.; Chiesa, R.; Matucci Cerinic, M.; Moggi Pignone, A.. - In: EUROPEAN JOURNAL OF INTERNAL MEDICINE. - ISSN 0953-6205. - 135:(2025), pp. 126-129. [10.1016/j.ejim.2025.03.019]
Doppler ultrasound unveils splanchnic arteries ischemia allowing early successful revascularization in symptomatic systemic sclerosis patients
Campochiaro C.;Baccellieri D.;Dagna L.;Chiesa R.;Matucci Cerinic M.;
2025-01-01
Abstract
Background: Systemic sclerosis (SSc) is characterized by macro and microvasculopathy, including splanchnic circulation. Chronic mesenteric ischemia (CMI) is a potentially severe condition which can complicate SSc gastrointestinal vasculopathy. Doppler ultrasound (DUS) may be a non-invasive procedure for identifying CMI in symptomatic SSc patients. Objectives: To investigate the capacity of DUS to detect early CMI and the effect of the endovascular approach on CMI-related symptoms. Methods: DUS of splanchnic arteries was performed in symptomatic SSc patients, during routinary outpatient visits. Results: In 6 out of 72 SSc symptomatic patients, DUS suggested a splanchnic vessels stenosis which was confirmed by computed tomography angiography (CTA). After multidisciplinary evaluation in 3 patients a revascularization was performed. Three-monthly clinical and DUS follow-up was negative in all patients. Conclusion: CDU is a useful screening tool for CMI in SSc patients. Revascularization of stenotic mesenteric arteries seems to be a safe and effective procedure.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
