Despite growing evidence about myocardial injury in hospitalized COronaVIrus Disease 2019 (COVID-19) patients, the mechanism behind this injury is only poorly understood and little is known about its association with SARS-CoV-2-mediated myocarditis. Furthermore, definite evidence of the presence and role of SARS-CoV-2 in cardiomyocytes in the clinical scenario is still lacking.

SARS-CoV-2, myocardial injury and inflammation: insights from a large clinical and autopsy study / Dal Ferro, Matteo; Bussani, Rossana; Paldino, Alessia; Nuzzi, Vincenzo; Collesi, Chiara; Zentilin, Lorena; Schneider, Edoardo; Correa, Ricardo; Silvestri, Furio; Zacchigna, Serena; Giacca, Mauro; Metra, Marco; Merlo, Marco; Sinagra, Gianfranco. - In: CLINICAL RESEARCH IN CARDIOLOGY. - ISSN 1861-0684. - 110:11(2021), pp. 1822-1831. [10.1007/s00392-021-01910-2]

SARS-CoV-2, myocardial injury and inflammation: insights from a large clinical and autopsy study

Metra, Marco;
2021-01-01

Abstract

Despite growing evidence about myocardial injury in hospitalized COronaVIrus Disease 2019 (COVID-19) patients, the mechanism behind this injury is only poorly understood and little is known about its association with SARS-CoV-2-mediated myocarditis. Furthermore, definite evidence of the presence and role of SARS-CoV-2 in cardiomyocytes in the clinical scenario is still lacking.
2021
COVID-19
Cardiac autopsy study
Myocardial injury
Myocarditis
Necrosis
Aged
Aged
80 and over
Autopsy
COVID-19
Cohort Studies
Female
Humans
Inflammation
Male
Myocarditis
Myocardium
Myocytes
Cardiac
SARS-CoV-2
Severity of Illness Index
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/193054
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