Istaroxime is a first-in-class agent which acts through inhibition of the sarcolemmal Na+ /K+ pump and activation of the SERCA2a pump. This study assessed the effects of a 24 h infusion of istaroxime in patients hospitalised for acute heart failure (AHF).

Treatment with 24 hour istaroxime infusion in patients hospitalised for acute heart failure: a randomised, placebo-controlled trial / Carubelli, Valentina; Zhang, Yuhui; Metra, Marco; Lombardi, Carlo; Felker, G Michael; Filippatos, Gerasimos; O'Connor, Christopher M; Teerlink, John R; Simmons, Phillip; Segal, Robert; Malfatto, Gabriella; La Rovere, Maria Teresa; Li, Dianfu; Han, Xiumin; Yuan, Zuyi; Yao, Yali; Li, Benjamin; Lau, Lit Fui; Bianchi, Giuseppe; Zhang, Jian. - In: EUROPEAN JOURNAL OF HEART FAILURE. - ISSN 1879-0844. - (2020). [10.1002/ejhf.1743]

Treatment with 24 hour istaroxime infusion in patients hospitalised for acute heart failure: a randomised, placebo-controlled trial

Metra, Marco;
2020-01-01

Abstract

Istaroxime is a first-in-class agent which acts through inhibition of the sarcolemmal Na+ /K+ pump and activation of the SERCA2a pump. This study assessed the effects of a 24 h infusion of istaroxime in patients hospitalised for acute heart failure (AHF).
2020
Inglese
Acute heart failure
Istaroxime
Outcomes
SERCA2a
Therapy
Treatment with 24 hour istaroxime infusion in patients hospitalised for acute heart failure: a randomised, placebo-controlled trial / Carubelli, Valentina; Zhang, Yuhui; Metra, Marco; Lombardi, Carlo; Felker, G Michael; Filippatos, Gerasimos; O'Connor, Christopher M; Teerlink, John R; Simmons, Phillip; Segal, Robert; Malfatto, Gabriella; La Rovere, Maria Teresa; Li, Dianfu; Han, Xiumin; Yuan, Zuyi; Yao, Yali; Li, Benjamin; Lau, Lit Fui; Bianchi, Giuseppe; Zhang, Jian. - In: EUROPEAN JOURNAL OF HEART FAILURE. - ISSN 1879-0844. - (2020). [10.1002/ejhf.1743]
none
20
info:eu-repo/semantics/article
262
Carubelli, Valentina; Zhang, Yuhui; Metra, Marco; Lombardi, Carlo; Felker, G Michael; Filippatos, Gerasimos; O'Connor, Christopher M; Teerlink, John R...espandi
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/193090
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