Chloride plays a role in renal salt sensing, neurohormonal activation, and regulation of diuretic targets, and hypochloremia predicts mortality in acute heart failure (AHF). AHF therapies, such as diuretics, alter chloride homeostasis. We studied the association between (changes in) chloride levels and diuretic responsiveness, decongestion, and mortality in patients with AHF.

Hypochloremia, Diuretic Resistance, and Outcome in Patients With Acute Heart Failure / Ter Maaten, Jozine M; Damman, Kevin; Hanberg, Jennifer S; Givertz, Michael M; Metra, Marco; O'Connor, Christopher M; Teerlink, John R; Ponikowski, Piotr; Cotter, Gad; Davison, Beth; Cleland, John G; Bloomfield, Daniel M; Hillege, Hans L; Van Veldhuisen, Dirk J; Voors, Adriaan A; Testani, Jeffrey M. - In: CIRCULATION. HEART FAILURE. - ISSN 1941-3289. - 9:8(2016). [10.1161/CIRCHEARTFAILURE.116.003109]

Hypochloremia, Diuretic Resistance, and Outcome in Patients With Acute Heart Failure

Metra, Marco;
2016-01-01

Abstract

Chloride plays a role in renal salt sensing, neurohormonal activation, and regulation of diuretic targets, and hypochloremia predicts mortality in acute heart failure (AHF). AHF therapies, such as diuretics, alter chloride homeostasis. We studied the association between (changes in) chloride levels and diuretic responsiveness, decongestion, and mortality in patients with AHF.
2016
blood urea nitrogen
chlorides
creatinine
diuretics
electrolytes
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/193474
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