In heart failure (HF), levels of NT-proBNP are influenced by the presence of concomitant atrial fibrillation (AF), making it difficult to distinguish between HF versus AF in patients with raised NT-proBNP. It is unknown whether levels of GDF-15 are also influenced by AF in patients with HF. In this study we compared the plasma levels of NT-proBNP versus GDF-15 in patients with HF in AF versus sinus rhythm (SR).

The influence of atrial fibrillation on the levels of NT-proBNP versus GDF-15 in patients with heart failure / Santema, Bernadet T; Chan, Michelle M Y; Tromp, Jasper; Dokter, Martin; Van Der Wal, Haye H; Emmens, Johanna E; Takens, Janny; Samani, Nilesh J; Ng, Leong L; Lang, Chim C; Van Der Meer, Peter; Ter Maaten, Jozine M; Damman, Kevin; Dickstein, Kenneth; Cleland, John G; Zannad, Faiez; Anker, Stefan D; Metra, Marco; Van Der Harst, Pim; De Boer, Rudolf A; Van Veldhuisen, Dirk J; Rienstra, Michiel; Lam, Carolyn S P; Voors, Adriaan A. - In: CLINICAL RESEARCH IN CARDIOLOGY. - ISSN 1861-0684. - (2019). [10.1007/s00392-019-01513-y]

The influence of atrial fibrillation on the levels of NT-proBNP versus GDF-15 in patients with heart failure

Metra, Marco;
2019-01-01

Abstract

In heart failure (HF), levels of NT-proBNP are influenced by the presence of concomitant atrial fibrillation (AF), making it difficult to distinguish between HF versus AF in patients with raised NT-proBNP. It is unknown whether levels of GDF-15 are also influenced by AF in patients with HF. In this study we compared the plasma levels of NT-proBNP versus GDF-15 in patients with HF in AF versus sinus rhythm (SR).
2019
Atrial fibrillation
Biomarkers
GDF-15
Heart failure
Natriuretic peptides
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/193548
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