Hyperkalaemia is a common co-morbidity in patients with heart failure with reduced ejection fraction (HFrEF). Whether it affects the use of renin-angiotensin-aldosterone system inhibitors and thereby negatively impacts outcome is unknown. Therefore, we investigated the association between potassium and uptitration of angiotensin-converting enzyme inhibitors (ACEi)/angiotensin receptor blockers (ARB) and its association with outcome.

Potassium and the use of renin-angiotensin-aldosterone system inhibitors in heart failure with reduced ejection fraction: data from BIOSTAT-CHF / Beusekamp, J.C., Tromp, J., Van Der Wal, H.H., Anker, S.D., Cleland, J.G., Dickstein, K., Filippatos, G., Van Der Harst, P., Hillege, H.L., Lang, C.C., Metra, M., Ng, L.L., Ponikowski, P., Samani, N.J., Van Veldhuisen, D.J., Zwinderman, A.H., Rossignol, P., Zannad, F., Voors, A.A., Van Der Meer, P.. - In: EUROPEAN JOURNAL OF HEART FAILURE. - ISSN 1388-9842. - (2018). [10.1002/ejhf.1079]

Potassium and the use of renin-angiotensin-aldosterone system inhibitors in heart failure with reduced ejection fraction: data from BIOSTAT-CHF

Metra, Marco;
2018-01-01

Abstract

Hyperkalaemia is a common co-morbidity in patients with heart failure with reduced ejection fraction (HFrEF). Whether it affects the use of renin-angiotensin-aldosterone system inhibitors and thereby negatively impacts outcome is unknown. Therefore, we investigated the association between potassium and uptitration of angiotensin-converting enzyme inhibitors (ACEi)/angiotensin receptor blockers (ARB) and its association with outcome.
2018
Guideline-directed medication
Heart failure
Hyperkalaemia
Outcome
Renin-angiotensin-aldosterone system inhibitors
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/193916
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