Subretinal hyperreflective material (SHRM) is a common and remarkable optical coherence tomography (OCT) biomarker whose importance is emerging in several retinal and chorioretinal diseases, including age-related macular degeneration, central serous chorioretinopathy, polypoidal choroidal vasculopathy, pathologic myopia, posterior uveitis, vitelliform lesions and macular dystrophies, and rarer disorders. Multimodal imaging, also thanks to the introduction of OCT angiography, allowed a deeper characterisation of SHRM components and its morphological changes after treatment, suggesting its usefulness in clinical practice. We discuss and summarize the nature, multimodal imaging characteristics, and prognostic and predictive significance of SHRM in the different retinal and choroidal disorders in which it has been described.

Subretinal hyperreflective material in retinal and chorioretinal disorders: A comprehensive review / Feo, A.; Stradiotto, E.; Sacconi, R.; Menean, M.; Querques, G.; Romano, M. R.. - In: SURVEY OF OPHTHALMOLOGY. - ISSN 0039-6257. - 69:3(2024), pp. 362-377. [10.1016/j.survophthal.2023.10.013]

Subretinal hyperreflective material in retinal and chorioretinal disorders: A comprehensive review

Sacconi R.;Menean M.;Querques G.;
2024-01-01

Abstract

Subretinal hyperreflective material (SHRM) is a common and remarkable optical coherence tomography (OCT) biomarker whose importance is emerging in several retinal and chorioretinal diseases, including age-related macular degeneration, central serous chorioretinopathy, polypoidal choroidal vasculopathy, pathologic myopia, posterior uveitis, vitelliform lesions and macular dystrophies, and rarer disorders. Multimodal imaging, also thanks to the introduction of OCT angiography, allowed a deeper characterisation of SHRM components and its morphological changes after treatment, suggesting its usefulness in clinical practice. We discuss and summarize the nature, multimodal imaging characteristics, and prognostic and predictive significance of SHRM in the different retinal and choroidal disorders in which it has been described.
2024
Age-related macular degeneration
Anti-VEGF therapy
Choroidal neovascularisation
Macular dystrophies
Macular neovascularisation
Pachychoroid disease
Pathologic myopia
Posterior uveitis
Subretinal hyperreflective material
Vitelliform material
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/198357
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