The Drug-Coated Balloon (DCB) Academic Research Consortium project originated from the need to overcome the lack of standardization and comparability among studies focusing on drug-coated balloon treatment. The DCB Academic Research Consortium represents a collaborative effort between academic research organizations and the most renowned interventional cardiology societies focusing on percutaneous coronary intervention in Europe, the United States, and Asia. The present consensus document provides a classification of DCB technologies, antiproliferative drugs, and types of elution and coatings. Moreover, by reviewing the available evidence on the use of DCBs for several lesion (restenosis, de novo small and large vessels, bifurcations) and clinical (acute coronary syndromes, diabetes mellitus, multivessel disease, high bleeding risk) settings, it seeks to provide reasonable suggestions for their clinical use. Last, this paper outlines the processes involved in optimal “lesion preparation” before the use of DCBs and the criteria used for assessing results following their use.

Indications for Use of Drug-Coated Balloons in Coronary Intervention: Academic Research Consortium Position Statement / Fezzi, S.; Serruys, P. W.; Cortese, B.; Scheller, B.; Alfonso, F.; Jeger, R.; Colombo, A.; Joner, M.; Shin, E. -S.; Kleber, F.; Latib, A.; Rissanen, T. T.; Eccleshall, S.; Ribichini, F.; Tao, L.; Koo, B. -K.; Chieffo, A.; Ge, J.; Granada, J. F.; Stoll, H. -P.; Spaulding, C.; Cavalcante, R.; Abizaid, A.; Muramatsu, T.; Boudoulas, K. D.; Waksman, R.; Mehran, R.; Cutlip, D.; Krucoff, M.; Stone, G. W.; Garg, S.; Onuma, Y.. - In: JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. - ISSN 0735-1097. - 86:15(2025), pp. 1170-1202. [10.1016/j.jacc.2025.07.049]

Indications for Use of Drug-Coated Balloons in Coronary Intervention: Academic Research Consortium Position Statement

Chieffo A.;
2025-01-01

Abstract

The Drug-Coated Balloon (DCB) Academic Research Consortium project originated from the need to overcome the lack of standardization and comparability among studies focusing on drug-coated balloon treatment. The DCB Academic Research Consortium represents a collaborative effort between academic research organizations and the most renowned interventional cardiology societies focusing on percutaneous coronary intervention in Europe, the United States, and Asia. The present consensus document provides a classification of DCB technologies, antiproliferative drugs, and types of elution and coatings. Moreover, by reviewing the available evidence on the use of DCBs for several lesion (restenosis, de novo small and large vessels, bifurcations) and clinical (acute coronary syndromes, diabetes mellitus, multivessel disease, high bleeding risk) settings, it seeks to provide reasonable suggestions for their clinical use. Last, this paper outlines the processes involved in optimal “lesion preparation” before the use of DCBs and the criteria used for assessing results following their use.
2025
coronary artery disease
drug-coated balloon
percutaneous coronary intervention
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/20.500.11768/201176
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