Thi s study ai me d to evaluate health-related quality of life o f patient s with prostatic can cer (PCa) undergoing ra di ation therapy. 28 pati en ts w ith newly diag nosed Pca and 25 heal thy subjects comp leted the followi ng que stionna ire s: EORTC QLQ-C30 , Internatio nal Pros tate Symp tom Sco re, In ternatio nal Inde x of Erec tile Fun ction at three tim e in te rvals: bas eline, mid-treatment, e nd of treatment. Mul tivaried va ria nce an aly sis in di cat ed th at ra dioth erapy is associat ed mainly to defici ts on p hysi cal dimension of quality of life (ge nit al and gastroi ntestin al toxicit y - but not urinary sy mptom s), while had n o effect on funct ion al, social, and emoti onal well -being, The to xicit y related to radio therapy is an importan t parameter for the quality of li fe of p atients with prostate cancer. What emerge d from th e study may he lp t he ps ych olo gist to direct his inter v ention to the issue s mostly afflicting the patie nts.
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