In allogeneic bone marrow transplantation, donor lymphocytes contribute to the development of GVHD, but can also confer protection,through graft versus leukemia, facilitating engraftment, and providing antiviral immunity. Here, Chiara Bonini and Claudio Bordignon summarize how a suicide gene in the delayed infusion of donor lymphocytes may help separate the two effects of donor lymphocytes.
Suicide gene therapy for control of graft-versus-host disease
BONINI, MARIA CHIARA;BORDIGNON , CLAUDIO
1999-01-01
Abstract
In allogeneic bone marrow transplantation, donor lymphocytes contribute to the development of GVHD, but can also confer protection,through graft versus leukemia, facilitating engraftment, and providing antiviral immunity. Here, Chiara Bonini and Claudio Bordignon summarize how a suicide gene in the delayed infusion of donor lymphocytes may help separate the two effects of donor lymphocytes.File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
